Leukocytes and systemic inflammatory response syndrome as prognostic factors in pulmonary embolism patients

BMC Pulmonary Medicine

Table 4 Reclassification of patients according to 30-day mortality based on the clinical model, RV/LV ratio, renal dysfunction, and SIRS satisfying the WBC criterion (Complete Case Analysis, n = 635)

Clinical model: shock on admission +altered mental state + active cancer	Clinical model + RV/LV ratio + renal dysfunction + SIRS satisfying the WBC criterion
	<10%	10%–30%	≥30%	Total
Non-survivors
<10%	20	15	0	35
10%–30%	0	11	5	16
≥30%	0	0	5	5
Total	20	26	10	56
Survivors
<10%	438	72	3	513
10%–30%	17	35	9	61
≥30%	0	0	5	5
Total	455	107	17	579

PE: pulmonary embolism; RV: right ventricle; LV: left ventricle; SIRS: systemic inflammatory response syndrome; WBC: white blood cell.
Reclassification tables for survivors or non-survivors of PE were constructed using PE risk categories [23], based on mortality prediction obtained by the clinical model and the clinical model + RV/LV ratio + renal dysfunction + SIRS satisfying WBC criterion, and included 3 categories: <10%, 10%–30%, and ≥30% of 30-day mortality.
For the 56 non-survivors, classification improved using the model with RV/LV ratio + renal dysfunction + SIRS satisfying the WBC criterion, but worsened for 20 subjects (cells in bold). For the 579 survivors, 17 subjects (cells in italics) were reclassified down and 84 subjects (cells in bold) were reclassified up.

ISSN: 1471-2466