An autopsy study of combined pulmonary fibrosis and emphysema: correlations among clinical, radiological, and pathological features

Table 4 Comparison of pathological features among the CPFE, IPF-alone, and emphysema-alone groups

	CPFE	IPF	Emphysema
	(n = 22)	(n = 8)	(n = 17)	p-value
TWCLs	16 (72.7%)	0	0	0.001
IP pattern
UIP	22 (100%)	8 (100%)	-	-
IP characteristics
Honeycombing	22 (100%)	8 (100%)	-	-
FF	6 (27.3%)	6 (75%)	-	0.027
FF in TWCLs	4 (25%)	-	-	-
Other characteristics
Bronchiolocentric fibrosis	3 (13.6%)	2 (25%)	0	0.405
DIP	0	0	0	-
RB	3 (13.6%)	0	0	0.379
DAD	6 (27.3%)	6 (75%)	0	0.027

TWCLs, thick-walled cystic lesions; IP, interstitial pneumonia; UIP, usual interstitial pneumonia.
FF, fibroblastic foci; DIP, desquamative interstitial pneumonia; RB, respiratory bronchiolitis.
DAD, diffuse alveolar damage; CPFE, combined pulmonary fibrosis and emphysema; IPF, idiopathic pulmonary fibrosis.

ISSN: 1471-2466