Table 3 Comparisons of cytokines in BALF and blood between pure and mixed PJP patients
Pure PJP (N =47) | Mixed PJP (N =18) | P value | |
|---|---|---|---|
BALF | |||
IL-1β, pg/ml | 2.13(1.66;2.91) | 4.59(1.92;24.45) | 0.024 |
TNF-α, pg/ml | 10.10(8.83;13.08) | 12.24(10.09;23.84) | 0.026 |
IL-8, pg/ml | 46.30(31.80;175.30) | 298.85(110.98;434.63) | 0.001 |
IL-17, pg/ml | 15.00(15.00;15.00) | 15.00(15.00;15.00) | 0.883 |
MCP-1, pg/ml | 1048.50(250.81;2842.70) | 1140.25(459.46;2171.44) | 0.649 |
IL-10, pg/ml | 3.90(3.90;7.70) | 3.90(3.90;3.90) | 0.152 |
TGF-β1, pg/ml | 49.60(42.10;60.30) | 46.55(44.88;59.33) | 0.899 |
IL-1RA, pg/ml | 1177.95(609.10;2816.00) | 1682.15(1174.78;4496.43) | 0.257 |
IL-1β/IL-10 | 0.48(0.35;0.56) | 1.18(0.29;5.22) | 0.018 |
TNF-α/IL-10 | 2.33(1.26;2.64) | 2.80(2.43;3.87) | 0.011 |
IL-8/IL-10 | 10.21(4.69;29.44) | 53.60(24.49;85.10) | 0.001 |
IL-17/IL-10 | 3.85(3.17;3.85) | 3.85(3.85;3.85) | 0.698 |
MCP-1/ IL-10 | 214.87(55.52;362.63) | 176.11(117.81;375.97) | 0.567 |
IL-1β/TGF-β1 | 0.04(0.02;0.05) | 0.11(0.03;0.42) | 0.002 |
TNF-α/TGF-β1 | 0.19(0.11;0.25) | 0.25(0.22;0.39) | 0.004 |
IL-8/TGF-β1 | 0.76(0.28;2.22) | 4.85(2.47;9.99) | <0.001 |
IL-17/TGF-β1 | 0.31(0.26;0.37) | 0.27(0.25;0.36) | 0.570 |
MCP-1/TGF-β1 | 10.48(0.96;42.87) | 18.54(10.85;39.91) | 0.182 |
IL-1β/IL-1RA | 0.00(0.00;0.00) | 0.01(0.00.0.02) | 0.048 |
TNF-α/IL-1RA | 0.01(0.00;0.02) | 0.01(0.00;0.02) | 0.743 |
IL-8/IL-1RA | 0.06(0.02;0.22) | 0.11(0.05;0.76) | 0.385 |
IL-17/IL-1RA | 0.01(0.01;0.03) | 0.01(0.00;0.02) | 0.385 |
MCP-1/IL-1RA | 0.99(0.23;1.52) | 0.65(0.08;1.59) | 0.905 |
Blood | |||
TNF-α, pg/ml | 12.00(9.00;17.10) | 12.25(7.55;20.68) | 0.829 |
IL-8, pg/ml | 30.41(18.78;53.40) | 71.80(32.90;136.33) | 0.008 |
IL-17, pg/ml | 15.00(15.00; 15.00) | 15.00(15.00; 15.00) | 0.832 |
MCP-1, pg/ml | 1271.70(402.90;2229.20) | 1928.80(525.95;3496.50) | 0.285 |
IL-10, pg/ml | 19.90(10.40;37.50) | 33.90(9.88;62.53) | 0.226 |
TGF-β1, pg/ml | 458.20(245.89;7768.70) | 5996.50(259.08;7819.45) | 0.288 |
IL-1RA, pg/ml | 884.00(354.68;2348.75) | 2160.40(402.80;6116.50) | 0.229 |
IL-8/IL-10 | 1.73(0.86;2.79) | 2.38(0.92;6.05) | 0.131 |
IL-8/TGF-β1 | 0.06(0.00;0.21) | 0.01(0.00;0.30) | 0.895 |
TNF-α/IL-10 | 0.56(0.35;1.12) | 0.35(0.19;1.19) | 0.284 |
TNF-α/TGF-β1 | 0.02(0.00;0.07) | 0.00(0.00;0.07) | 0.215 |