Table 2 Baseline characteristics of study subjects by one-year outcome status among HIV-1-infected pulmonary tuberculosis patients, Uganda, 1993–1995
Characteristic | Favorable Outcome (Alive and cured at 1-year) (N = 169) | Unfavorable Outcome (Dead or not cured at 1-year) (N = 45) | p value |
|---|---|---|---|
Categorical variables: | n (%) | n (%) | |
Demographic | |||
Educated | 157 (92.9) | 45(100) | 0.02 |
Married | 135(79.9) | 37(82.2) | 0.72 |
Past Medical History | |||
Fever | 102(60.4) | 34(75.6) | 0.06 |
Cough | 165(97.6) | 45(100) | 0.30 |
Sweats | 109(64.5) | 30(66.7) | 0.79 |
Hemoptysis | 20(11.8) | 4(8.9) | 0.58 |
Diarrhea | 17(10.1) | 9(20.0) | 0.07 |
Herpes zoster | 6(3.6) | 3(6.7) | 0.36 |
Genital ulcers | 32(18.9) | 11(24.4) | 0.41 |
Thrush | 5(3.0) | 12(26.7) | <0.005 |
BCG scar | 93(55.0) | 25(55.6) | 0.95 |
Chest radiography | |||
Cavitary disease | 104(61.5) | 22(48.9) | 0.12 |
Fibrosis | 37(21.9) | 3(6.7) | 0.02 |
Upper lung disease | 140(82.8) | 33(73.3) | 0.15 |
Continuous variables: | Means (SD) | Means (SD) | |
Age (years) | 29.1(6.2) | 29.5(6.4) | 0.69 |
Weight (Kg) | 51.9(7.5) | 49.0(8.1) | <0.005 |
Body mass index (Kg/m2) | 19.5(2.7) | 18.4(2.6) | <0.005 |
Tuberculin skin test result (mm) | 15.7(6.2) | 10.8(7.2) | <0.005 |
β2 microglobulin (g) | 6.2(2.5) | 6.9(4.3) | <0.005 |
Absolute CD4 cell count (cells/μl) | 428(313) | 207(273) | <0.005 |
Hemoglobin (g/dl) | 10.6(2.2) | 9.6(2.5) | 0.01 |
WBC (cells × 1000/ μl) | 7.6(2.6) | 7.1(3.4) | 0.41 |
Duration of symptoms (months) | |||
Fever | 2.5(2.5) | 3.1(3.7) | 0.39 |
Sweats | 2.8(2.7) | 2.0(1.9) | 0.09 |
Diarrhea | 1.3(1.7) | 1.4(1.6) | 0.89 |
Signs | |||
Temperature (° Celsius) | 37.0(1.9) | 37.0(1.0) | 0.95 |
Karnofsky score (%) | 83.1(6.1) | 79.1(7.3) | <0.005 |
Extent of disease on x-ray | 2.5(0.7) | 2.3 (0.7) | 0.15 |