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Table 2 Leukocyte and lymphocyte subsets

From: Diffuse parenchymal lung disease as first clinical manifestation of GATA-2 deficiency in childhood

 

Initial investigation

After 2-year follow-up

Normal values

 

Ă— 10^9/l (%)

Ă— 10^9/l (%)

Ă— 10^9/l (%)

Leukocytes

2.8

5.4

4.0 - 10.0

Monocytes

0.014 (0.5*)

0.028 (0.5*)

0.12 - 1.0 (3 - 10*)

Lymphocytes

0.773 (27.6*)

2.120 (39.3*)

1.0 - 3.3 (25 - 33*)

T cells (CD3+)

0.659 (85.3**)

1.696 (80.0**)

2.0 - 6.5 (55 - 88**)

B cells (CD19+)

0.015 (1.9**)

0.042 (2.0**)

0.4 - 3.3 (11 - 45**)

NK cells (CD56 + 16+)

0.085 (11.0**)

0.382 (18.0**)

0.1 - 1.0 (6 - 26**)

CD4/8 index

1.3

1.7

1 - 3

  1. Legend: The initial leuko- and lymphopenia resolved; the profound monocyto- and B-cell lymphopenia persisted. The B cells were predominantly of memory phenotype. Myeloid as well as plasmacytoid dendritic cells were missing. In the parenthesis percentage of cells out of (*) leukocytes and (**) lymphocytes, respectively, are shown.