Figure 5

Correlations of rates of recovery following Ca²⁺uncaging in ASM cells with clinical lung function parameters in respective patient donors. Recovery rates compared to the FEV₁% predicted (A, C, E) and FEV₁/FVC% (B, D, F) are shown in the absence of inhibitor (−CPA, ●, A, B), in the presence of CPA (+CPA, ○, C, D), or for the difference between –CPA and + CPA recovery rates (ΔK, ▲, E, F). Data were analyzed by Spearman correlation (95% confidence interval).