Figure 6

Collagen gel contraction assay of human airway smooth muscle cells. (A) Percentage contraction of collagen gels impregnated with airway smooth muscle from donors who are not asthmatic (n = 5) and donors with asthma (n = 12) over 1 hour following stimulation with 1 nM bradykinin. (B) Area under the curve gel contraction. Symbol key: filled circles: GINA 1–3; open circles: GINA 4–5; filled squares: non-asthmatic donors. Data are shown as mean ± SEM and analysed by Student’s t-test.