Table 1 Clinical characteristics of patients with suspected LIP
Definite LIP | Non-LIP | Probable LIP | Definite & probable LIP | P value | |
|---|---|---|---|---|---|
n = 13 | n = 10 | n = 19 | n = 32 | ||
Demographic characteristics | |||||
Age median (range) | 34 (21–57)* | 42 (26–66)* | 39(20–52) | 35 (20–57) | *p = 0.11 |
Gender: Female n (%) | 11(85%)* | 3 (30%)*# | 15 (79%) | 20 (77%)# | *p = 0.006 |
#p = 0.008 | |||||
CD4 count median (range) | 194 (104–464)* | 157(51–323)* | 216 (30–444) | 216 (30–464) | p = 0.18 |
Number of participants on ARV at presentation | 1/11 (9%) | 5/8 (62.5%)* | 8/13 (61.5%) | 9/24(37.5%)* | *p = 0.25 |
Symptoms | |||||
Duration in months Median (range) | 5 (1–84) | 4 (.75-12) | 6 (0.5-24) | 6 (0.5-84) | p = 0.45 |
Presence of cough | 10/11 (90%) | 10/10 (100%) | 16/18 (88%) | 26/29(89.7%) | |
Productive cough | 7/11 (64%)* | 6/10(60%)* | 12/16 (75%) | 19/27 (71%) | *p = 0.43 |
Dyspnea (NHYA) | |||||
Class 1 | 3 (25%) | 2 (20%) | 6 (33%) | 9 (30%) | |
Class 2 | 8 (67%) | 4 (40%) | 9 (50%) | 17 (57%) | |
Class 3 | 1(3%) | 3 (30%) | 3 (17%) | 4 (13%) | |
Class 4 | 0 | 1 (10%) | 0(0%) | 0 | |
Referral diagnosis of non-resolving TB | 77% | 70% | 86% | ||
Examination findings | |||||
BMI kg/cm2 mean (SD) | 25.3(5.3) | 23.8(6.2) | 23.9(5.4) | 24.6(5.2) | p = 0.94 |
Presence of clubbing | 0/ 11 (0%) | 3/10 (30%) | 6/18(33%) | 6/29 (20%) | |
Auscultation | |||||
Normal | 4 (33%) | 2 (20%) | 7 (39%) | 11 (38%) | |
Bibasilar crackles | 7 (58%) | 6 (60%) | 9 (50%) | 16 (55%) | |
Diffuse crackles | 0 | 1(10%) | 2 (11%) | 2 (7%) | |
Wheeze | 0 | 0 | 0 | 0 | |
Bronchial breathing | 1 (8%) | 1(10%) | 0 | 0 | |