Table 2 Characteristics of patients with idiopathic pulmonary arterial hypertension (IPAH) and healthy subjects

Age [yr]

58 ± 16

58 ± 15

0.97

Gender female/male [n]

12/4

6/4

0.42^a

BMI [kg/m²]

25 ± 6

24 ± 3

0.75

6MWD [m]

490 ± 100

638 ± 110

0.002

NT-proBNP [ng/l]

667 ± 594

68 ± 27

0.004

 Workload max [W]

73 ± 32

130 ± 46

0.005

 Peak VO₂/kg [ml/min/kg]

15 ± 4

23 ± 5

0.001

 Peak VO₂ [l/min]

1.1 ± 0.4

1.7 ± 0.6

0.001

 EqCO₂ at AT [l/min/l/min]

47 ± 7.6

32 ± 2.2

<0.001

 VO₂ at AT [l/min]

0.8 ± 0.2

1.2 ± 0.2

0.002

 HR rest/max [/min]

78 ± 12/129 ± 28

77 ± 11/138 ± 18

0.90/0.35

 BP systolic rest/max [mm Hg]

102 ± 20/149 ± 30

118 ± 22/179 ± 22

0.06/0.01

 BP diastolic rest/max [mm Hg]

69 ± 12/80 ± 12

75 ± 10/81 ± 13

0.25/0.60

 FEV₁ % predicted [%]

78 ± 13

94 ± 8

0.002

 FVC % predicted [%]

87 ± 13

95 ± 8

0.11

 FEV₁/FVC [%]

86 ± 11

102 ± 7

<0.001

 DLCO % predicted [%]

76 ± 15

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