Table 1 Baseline Patient Demographic and Clinical Characteristics

Women, n (%)

28 (68)

33 (77)

26 (58)

Age, y

42.5 (16.5)

44.4 (17.4)

46.4 (17.7)

 Range

18–77

18–78

20–88

 White

11 (27)

11 (26)

14 (31)

 Black

2 (5)

2 (5)

1 (2)

 Asian

27 (66)

30 (70)

30 (67)

 Other

1 (2)

0

0

Height, cm

159.0 (11.3)

160.2 (10.7)

160.7 (8.7)

 Range

130.0–181.6

129.0–189.0

147.0–181.0

Weight, kg

61.7 (17.0)

63.1 (19.7)

61.4 (15.7)

 Range

32.0–117.0

26.5–126.1

35.0–100.0

BMI, kg/m²

24.3 (5.6)

24.3 (6.6)

23.8 (6.2)

 Range

15.6–35.8

13.3–42.1

15.6–38.6

 I

0

1 (2.3)

3 (6.7)

 II

25 (61.0)

22 (51.2)

27 (60.0)

 III

16 (39.0)

16 (37.2)

13 (28.9)

 IV

0

1 (2.3)

0

 Missing

0

3 (7.0)

2 (4.4)

 Idiopathic

30 (73)

31 (72)

34 (76)

 Mean duration (range) since diagnosis, y

1.1 (0–6.7)

0.7 (0–6.5)

0.9 (0–14.9)

 Associated with CTD

6 (15)

8 (19)

5 (11)

 Mean duration (range) since diagnosis, y

0.6 (0–2.3)

0.4 (0–1.8)

0.4 (0–1.9)

 Associated with surgical repair

5 (12)

4 (9)

6 (13)

 Mean duration (range) since diagnosis, y

5.9 (0.3–14.2)

3.5 (0–7.3)

4.5 (0–15.7)

6MWD, m^a

347.5 (67.3)

347.7 (73.4)

340.4 (76.3)

 Range

167.5–441.5

109.0–455.0

114.0–429.0

Heart rate, bpm^b

83.6 (17.2)

78.9 (16.4)

80.1 (15.0)

 Range

48–122

42–113

53–110

RAP, mmHg^c

10.5 (5.1)

10.1 (6.1)

8.4 (4.7)

 Range

4.0–20.0

2.0–23.0

2.0–27.0

mPAP, mmHg^c

57.2 (21.9)

55.4 (19.7)

51.1 (21.4)

 Range

25.0–110.0

26.3–117.0

25.0–106.0

Cardiac index, L/min/m^2d

2.1 (0.7)

2.3 (0.6)

2.8 (1.2)

 Range

1.0–3.5

1.0–3.8

1.1–5.9

PVR, Wood units^e

15.7 (9.9)

13.2 (8.3)

11.7 (9.1)

 Range

3–43

3–48

2–35

MVO₂, %^f

63.4 (10.5)

63.0 (9.6)

64.3 (14.5)

 Range

41–82

42–77

31–90

TAPSE index^g

1.25 (0.62)

1.2 (0.71)

1.36 (0.83)

 Range

0.1–2.6

0.1–2.5

0.2–2.8

Borg dyspnea score^h

2.9 (2.5)

3.1 (1.9)

2.8 (2.1)

 Range

0–10

0–8

0–9