Table 5 Comparison of patients by antibiotic treatment: penicillin-G/V monotherapy versus broad-spectrum antibiotics
Monotherapy penicillin-G/V | Other than penicillin-G/V monotherapy | p-value | |
|---|---|---|---|
n = 590 | n = 725 | ||
Age, median (IQR) | 70.5 (57–81) | 72 (59–82) | 0.30b |
CURB-65 | |||
0–1 | 58.8% (295/502) | 48.6% (306/630) | <0.0001a |
2 | 29.1% (146/502) | 29.1% (183/630) | |
3–5 | 12.1% (61/502) | 22.3% (141/630) | |
Co-morbidities | |||
0 | 45.1% (264/585) | 35.1% (252/718) | 0.001a |
1 | 32.8% (192/585) | 37.7% (271/718) | |
> 1 | 22.1% (129/585) | 27.2% (194/718) | |
ICU admission | 6.1% (36/590) | 12.6% (91/725) | <0.0001a |
In-hospital mortality rate | 6.4% (38/590) | 10.1% (73/725) | 0.02a |
90 day mortality rate | 11.7% (69/590) | 18.5% (134/720) | <0.0009a |