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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

Fig. 3

Analysis of type 1 collagen α1 (COL1A1) and interleukin-6 (IL-6) levels in the supernatant of cells, serum and bronchoalveolar lavage fluid (BALF). They were measured by enzyme-linked immunosorbent assay (ELISA). Data are expressed as the mean ± SD. a and b: COL1A1 and IL-6 levels in the supernatant of cells after TGF-β1 and various concentrations of PFD stimulation (*P < 0.05, **P < 0.01, vs. TGF-β1 group). c and d: Serum COL1A1 and IL-6 after BLM and PFD treatment (*P < 0.05, **P < 0.01, vs. BLM 14d and 42d group). e and f: COL1A1 and IL-6 levels in BALF after BLM and PFD treatment (*P < 0.05, **P < 0.01, vs. BLM 14d and 42d group)

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BMC Pulmonary Medicine

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