Exploratory analysis of the neutrophil to lymphocyte ratio in patients with pulmonary arterial hypertension

BMC Pulmonary Medicine

Table 1 Demographic, functional and hemodynamic characteristics of patients with pulmonary arterial hypertension (PAH)

Parameters	PAH patients (n = 77)
Age, years	61 ± 14
Gender female/male	58/19
WHO-FC I/II/III/IV	2/13/50/12
6MWD, m	355 ± 135
NT-proBNP, ng/l	3274 ± 4750
GFR, ml/min/1.73 m²	72 ± 50
CRP > 5/≤ 5, mg/dl	26/50
mPAP, mm Hg	43 ± 16
RAP, mm Hg	9 ± 5
PAWP, mm Hg	12 ± 6
PVR, dyn · s · cm⁻⁵	822 ± 645
SvO₂, %	62 ± 12
CI, l/min/m²	2.21 ± 1.14
RVSP, mm Hg	59 ± 23
TAPSE, mm	18 ± 6
Arterial hypertension	32 (42%)
Diabetes mellitus	10 (13%)
Coronary heart disease	12 (16%)
Atrial fibrillation	15 (20%)
BMI ≥ 30 kg/m²	17 (22%)
CVRF ≥ 3^a	7 (9%)
Chronic obstructive pulmonary disease	16 (21%)

Data are presented as mean ± standard deviation or numbers. ^aCVRF including arterial hypertension, diabetes mellitus, coronary heart disease, atrial fibrillation and body mass index
6MWD 6 minute walking distance, CVRF cardiovascular risk factors, CI cardiac index, CRP C-reactive protein, GFR glomerular filtration rate, mPAP mean pulmonary arterial pressure, NT-proBNP N-terminal of the prohormone brain natriuretic peptide, PVR pulmonary vascular resistance, RAP right atrial pressure, RVSP right ventricular systolic pressure, SvO ₂ oxygen saturation of mixed venous blood, TAPSE tricuspid annular plane systolic excursion, WHO-FC World Health Organization functional class

ISSN: 1471-2466