Table 3 Univariable Cox’s proportional hazards regression analyses regarding transplantation-free survival in patients with pulmonary arterial hypertension (PAH)

Neutrophils, 10⁶/ml

1.03

0.92–1.14

0.644

Neutrophils, %

1.06

1.02–1.1

0.002

Lymphocytes, 10⁶/ml

0.37

0.17–0.83

0.016

Lymphocytes, %

0.22

0.90–0.99

0.022

Neutrophil/lymphocyte ratio

1.05

1.01–1.08

0.006

Eosinophils, > 0.1 10⁶/ml

0.79

0.35–1.77

0.537

Age, years

1.01

0.98–1.04

0.454

Male gender

1.42

0.68–2.96

0.346

Prevalent vs. incident PAH

0.70

0.36–1.36

0.296

Idiopathic PAH vs. non-idiopathic PAH

2.17

1.11–4.24

0.023

WHO-FC

2.62

1.32–5.15

0.005

6WMD, >380 m

0.29

0.10–0.87

0.027

NT-proBNP, > 3474 ng/l

2.33

1.19–4.57

0.014

CRP > 5 mg/dl

2.05

1.04–4.05

0.039

GFR > 60 ml/min/1.73 m²

0.38

0.19–0.74

0.004

mPAP, mm Hg

1.02

0.99–1.04

0.142

Cardiac index, ml/min/m²

0.58

0.55–1.39

0.580

PVR, dyn*s*cm⁻⁵

1

1–1.01

0.13

RAP, mm Hg

1.06

0.99–1.14

0.108

SvO₂, %

0.96

0.96–0.99

0.007

Arterial hypertension

0.78

0.39–1.54

0.470

Diabetes mellitus

0.76

0.27–2.17

0.618

Coronary heart disease

1.67

0.80–3.46

0.171

Atrial fibrillation

0.91

0.34–2.46

0.858

BMI ≥ 30 kg/m²

1.05

0.39–2.81

0.92

CVRF ≥ 3^a

0.76

0.18–3.27

0.716

Chronic obstructive pulmonary disease

0.67

0.26–1.72

0.405