Table 1 Patient age, gender and mean and standard deviations of pulmonary function indices, CALIPER and visually scored CT parameters, and echocardiography data in patients with chronic hypersensitivity pneumonitis. Data represent mean values with standard deviations. CT computed tomography, FEV1 forced expiratory volume in one second, FVC forced vital capacity, DLco diffusing capacity for carbon monoxide, Kco carbon monoxide transfer coefficient, TLC total lung capacity, CPI composite physiological index, ILD interstitial lung disease, RVSP right ventricular systolic pressure, TxBx = traction bronchiectasis. Baseline variables in patients with hypersensitivity pneumonitis
Variable (n = 116 unless stated) Units are percentage unless stated | Value |
|---|---|
Median Age (years) | 58 · 5 |
Male/female | 39/77 |
Survival (alive/dead) | 77/39 |
Never smokers/ever/current-smokers (n = 128) | 71/42/2 |
Pack years | 17.5 ± 16.2 |
Follow up time (months) | 58.0 ± 17 · 5 |
FEV1 % predicted (n = 112) | 68 · 6 ± 19 · 7 |
FVC % predicted (n = 112) | 72 · 2 ± 22 · 8 |
DLco % predicted (n = 109) | 42 · 9 ± 15 · 8 |
Kco % predicted (n = 109) | 70 · 1 ± 16 · 3 |
TLC% predicted (n = 103) | 72 · 0 ± 16 · 8 |
CPI (n = 108) | 47 · 9 ± 15 · 2 |
Echocardiography RVSP (mmHg) (n = 58) | 35 · 0 ± 14 · 9 |
CALIPER ILD extent | 24 · 3 ± 22 · 5 |
CALIPER Fibrosis extent | 4 · 8 ± 4 · 1 |
CALIPER Ground glass opacity | 19 · 6 ± 20 · 9 |
CALIPER Reticular pattern | 4 · 4 ± 3 · 9 |
CALIPER Honeycombing | 0 · 3 ± 0 · 6 |
CALIPER Emphysema | 0 · 5 ± 1 · 7 |
CALIPER Pulmonary vessel volume | 4 · 5 ± 1 · 9 |
CALIPER Normal lung | 70 · 7 ± 23 · 8 |
Visual ILD extent | 62 · 1 ± 24 · 6 |
Visual fibrosis extent | 27 · 4 ± 19 · 0 |
Visual Ground glass opacity | 33 · 4 ± 24 · 0 |
Visual Reticular pattern | 26 · 4 ± 18 · 2 |
Visual Honeycombing | 0 · 9 ± 4 · 1 |
Visual Consolidation | 0 · 8 ± 3 · 3 |
Visual Mosaicism | 5.0 ± 7 · 1 |
Visual Emphysema | 3 · 0 ± 8v4 |
Visual TxBx severity (max score 18) | 5 · 9 ± 4 · 7 |
Main pulmonary artery diameter (mm) | 29 · 6 ± 4 · 9 |
Ascending aorta diameter (mm) | 33 · 1 ± 3 · 9 |
Pulmonary artery:ascending aorta ratio | 0.9 ± 0 · 1 |