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Table 2 Therapeutic interventions and outcomes and causes of death in the study cohort

From: Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study

 

Azithromycin

n = 38

Fluoroquinolone

n = 47

p value

High-dose steroid pulse therapy

38 (100)

47 (100)

1

Beta-lactam combination:

6 (16)

5 (11)

0.5

PMX

0 (0)

2 (3.5)

1

Invasive mechanical ventilation

0 (0)

6 (13)a

0.03

Noninvasive mechanical ventilation

10 (26)

21 (45)

0.11

High-flow nasal cannula

3 (8)

0 (0)

0.09

DNI

19 (50)

32 (68)

0.12

60-day mortality

10 (26)

33 (70)

<0.001

Respiratory death

10/10 (100)

33/33 (100)

1

  1. Data are presented as n (%)
  2. Abbreviations: PMX polymyxin B-immobilized fiber column-direct hemoperfusion, DNI do not intubate
  3. aFive patients underwent NIMV before IMV