HR | 95% CI | p value | |
---|---|---|---|
Age | 1.02 | 0.98–1.05 | 0.31 |
Male sex | 0.74 | 0.38–1.45 | 0.38 |
IPF diagnosis | |||
Possible UIP with traction bronchiectasis | 1 | 0.36–2.80 | 0.99 |
Surgical lung biopsy, Yes | 1.08 | 0.52–2.26 | 0.83 |
HRCT pattern of AE | |||
Multifocal | 0.41 | 0.10–1.71 | 0.22 |
Corticosteroid use before admission | 0.75 | 0.41–1.38 | 0.38 |
Immunosuppressant before admission | 1.19 | 0.60–2.36 | 0.62 |
Antifibrotic drug before admission | 1.11 | 0.51–2.38 | 0.80 |
Anticoagulant drug before admission | 1.40 | 0.50–3.91 | 0.52 |
APACHE II score | 1.12 | 1.03–1.21 | 0.008 |
PaO2/FiO2 | 0.99 | 0.99–1 | 0.04 |
Lactate dehydrogenase (IU/L) | 1 | 1.001–1.006 | 0.002 |
C-reactive protein (mg/dl) | 1.05 | 1.0–1.1 | 0.04 |
KL-6 (U/ml) | 1 | 0.99–1 | 0.49 |
Surfactant protein D (ng/ml), n = 75 | 1 | 0.99–1 | 0.23 |
Invasive mechanical ventilation | 2.34 | 0.92–5.98–3.52 | 0.07 |
Noninvasive mechanical ventilation | 1.85 | 1.01–3.37 | 0.047 |
High flow nasal cannula | 0.53 | 0.07–3.89 | 0.54 |
Combination beta lactam | 0.74 | 0.29–1.87 | 0.53 |
Azithromycin use | 0.28 | 0.14–0.57 | <0.001 |