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Table 3 Measures describing how well blood cultures and SeptiFast polymerase chain reaction analyses capture the true presence or absence of disease, as related to gold standard, with 95% confidence interval

From: Bacteraemia and fungaemia in cystic fibrosis patients with febrile pulmonary exacerbation: a prospective observational study

 

Test

 

% (95% CI)

SF

BC

P value

ROP

13.2% (6.7%–17.8%)

7.3% (2.8%–17.8%)

0.322

Sensitivity

85.7% (48.6%–97.5%)

42.9% (10.2%–83.2%)

0.250

Specificity

96.9% (87.9%–99.3%)

96.9% (88.6%–99.2%)

1.000

PPV

74.7% (36.0%–93.9%)

60.2% (18.5%–90.1%)

0.255

NPV

98.4% (89.3%–99.8%)

87.0% (86.2%–94.1%)

0.105

  1. SF SeptiFast polymerase chain reaction analysis, BC blood culture, ROP rate of positivity, PPV positive predictive value, NPV negative predictive value
  2. P value: Two-sided P value of the null hypothesis of equal ROP, sensitivity, specificity, PPV, and NPV of SF and BC
  3. Sensitivity: P (Test = positive | gold standard = positive)
  4. Specificity: P (Test = negative | gold standard = negative)
  5. PPV: P (gold standard = positive | Test = positive)
  6. NPV: P (gold standard = negative | Test = negative)
  7. ROP: P (Test = positive)
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BMC Pulmonary Medicine

ISSN: 1471-2466

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