Table 1 Baseline of all patients with non-severe CAP

Sex, female n (%)

675 (41)

626 (42)

49 (35)

0.115

Age(year), Median (Q1, Q3)^a

58 (45, 69)

57 (44, 68)

67 (54, 76)

< 0.001

BMI(Kg/m²), Median (Q1, Q3)

22.43(20.42, 24.92)

22.39(20.42, 24.81)

23.1(20.76, 26.44)

0.036

Hypertension, n (%)

495 (30)

441 (30)

54 (38)

0.04

Diabetes, n (%)

210 (13)

187 (13)

23 (16)

0.252

Cardiovascular disease^c, n (%)

155 (9)

127 (9)

28 (20)

< 0.001

Liver disease, n (%)

133 (8)

124 (8)

9 (6)

0.521

Gastrointestinal diseases, n (%)

71 (4)

67 (4)

4 (3)

0.48

Chronic kidney disease, n (%)

29 (2)

26 (2)

3 (2)

0.734

Cerebrovascular disease, n (%)

66 (4)

55 (4)

11 (8)

0.032

Basic lung disease^b, n (%)

78 (5)

67 (4)

11 (8)

0.12

Pleural effusion, n (%)

441 (27)

385 (26)

56 (40)

< 0.001

Bilateral lung lesions, n (%)

759 (47)

679 (46)

80 (57)

0.014

Time interval between onset and admission(day), Median (Q1, Q3)

7 (4, 10)

7 (4, 10)

6 (4, 10)

0.448

Duration of antibiotic use before admission(day), Median (Q1, Q3)

2.5 (1, 4)

3 (1, 4)

2 (1, 4)

0.545

Body temperature(℃), Median (Q1, Q3)

37.1(36.7, 37.8)

37.1 (36.7, 37.7)

37.5(36.9, 38.5)

< 0.001

Systolic pressure(mmHg), Median (Q1, Q3)

123(111, 138)

123 (110, 137)

128(115, 141)

0.014

Diastolic pressure(mmHg), Median (Q1, Q3)

76 (69, 84)

76 (69, 84)

76 (67, 84)

0.297

Respiratory rate(/min), Median (Q1, Q3)

20 (20, 20)

20 (20, 20)

20 (20, 20)

< 0.001

Pulse(/min), Median (Q1, Q3)

88 (78, 100)

88 (77, 99)

91 (80, 103)

0.005

SpO₂(%), Median (Q1, Q3)

97 (95, 98)

97 (95, 98)

96 (94, 97)

< 0.001

WBC(×10⁹/L), Median (Q1, Q3)

7.16(5.48, 9.89)

7.06 (5.46, 9.7)

8.72(5.82, 11.99)

< 0.001

ANC(×10⁹/L), Median (Q1, Q3)

5.04(3.46, 7.6)

4.91 (3.4, 7.37)

6.54(4.21, 9.62)

< 0.001

LYM(×10⁹/L), Median (Q1, Q3)

1.3(0.96, 1.72)

1.33 (0.98, 1.75)

1.06(0.74, 1.43)

< 0.001

RBC(×10¹²/L), Median (Q1, Q3)

4.16(3.8, 4.55)

4.17 (3.81, 4.56)

4.12(3.74, 4.48)

0.06

HB(g/L), Median (Q1, Q3)

126(114, 138)

126 (115, 138)

123 (111, 136)

0.023

PLT(×10⁹/L), Median (Q1, Q3)

241(184, 307)

242 (186, 307)

228 (170, 312)

0.22

CRP(mg/L), Median (Q1, Q3)

61.15(19.9, 114.78)

56.9 (17.7, 110.36)

102(56.3, 173)

< 0.001

PCT(ng/ml, Median (Q1, Q3)

0.09(0.04, 0.29)

0.08 (0.04, 0.25)

0.17(0.08, 0.73)

< 0.001

TBIL(µmol/L), Median (Q1, Q3)

8 (6, 12)

8 (6, 12)

10 (7, 15)

< 0.001

ALT(U/L), Median (Q1, Q3)

23(14, 44.25)

23 (14, 43)

26 (16, 49)

0.067

AST(U/L), Median (Q1, Q3)

25 (19, 39)

24 (18, 38)

35 (22, 53)

< 0.001

ALB(g/L), Mean ± SD

36.23 ± 5.4

36.54 ± 5.34

32.9 ± 4.92

< 0.001

BUN(mmol/L), Median (Q1, Q3)

4.6 (3.6, 6)

4.6 (3.6, 5.9)

5 (3.7, 6.9)

0.02

Cr(µmol/L), Median (Q1, Q3)

66 (55, 80)

65 (55, 80)

72 (55, 86)

0.038

eGFR, Median (Q1, Q3)

100.2(85.68, 113.8)

101.1(87.05, 114.15)

92.6(77.1, 107.9)

< 0.001

UA(µmol/L), Median (Q1, Q3)

252.5(193, 316)

253 (195.5, 315.5)

228 (161, 325)

0.031

K⁺(mmol/L), Median (Q1, Q3)

3.75(3.49, 4.01)

3.76 (3.5, 4.01)

3.74(3.42, 4.01)

0.229

Na⁺(mmol/L), Median (Q1, Q3)

139(136.75, 141)

139 (137, 141)

138(135, 140)

< 0.001

CL⁻(mmol/L), Median (Q1, Q3)

103(100, 105)

103 (100, 105)

102 (99, 104)

0.002

TC(mmol/L), Median (Q1, Q3)

4.11(3.51, 4.79)

4.15 (3.56, 4.81)

3.73 (3.1, 4.47)

< 0.001

TG(mmol/L), Median (Q1, Q3)

1.08(0.82, 1.49)

1.08 (0.82, 1.5)

1.03(0.85, 1.38)

0.237

HDL(mmol/L), Median (Q1, Q3)

0.92(0.74, 1.14)

0.93 (0.75, 1.15)

0.86(0.65, 1.05)

< 0.001

LDL(mmol/L), Median (Q1, Q3)

2.4(1.91, 2.92)

2.43 (1.93, 2.96)

2.06(1.6, 2.52)

< 0.001

CK(U/L), Median (Q1, Q3)

71 (47, 113)

70 (48, 111)

84 (44, 158)

0.061

LDH(U/L), Median (Q1, Q3)

213(178, 256)

210 (176, 252)

248(202, 320)

< 0.001

D-Dimer(mg/L), Median (Q1, Q3)

0.75(0.39, 1.54)

0.71 (0.38, 1.46)

1.33(0.81, 2.12)

< 0.001