Table 1 Basic characteristics of patients included in the study
Characteristic (n = 228) | data |
|---|---|
Sex, No. (%) | Â |
Female | 108 (47.4%) |
Male | 120 (52.6%) |
Age (years) | 53.0 (38.0–62.0) |
Age of diagnosis (years) | 40.0 (22.3–50.8) |
Duration of asthma | 7.0 (4.0–19.0) |
BMI, kg/m2 | Â |
Underweight (< 18.5) | 8 (3.5%) |
Normal (≥ 18.5 to < 24) | 95 (41.7%) |
Overweight (≥ 24 to < 28) | 90 (39.5%) |
Obesity (≥ 28) | 35 (15.4%) |
Smoking status | Â |
Current smoker | 15 (6.6%) |
Ex-smoker | 43 (18.9%) |
Never smoked | 170 (74.6%) |
Allergen-specific IgE (n = 181) | Â |
positive hx2-positive | 120 (66.3%) 96 (53.0%) |
mx2-positive | 34 (18.8%) |
fx5-positive | 20 (11.0%) |
wx5-positive | 16 (8.8%) |
tx4-positive | 14 (7.7%) |
negative | 61 (33.7%) |
GINA classification | Â |
Step 4 | 133 (58.3%) |
Step 5 | 95 (41.7%) |
Laboratory findings | Â |
Blood neutrophil (%) (n = 159) | 57.3 (50.7–64.9) |
Blood neutrophil (/ul) (n = 157) | 4000.0 (3300.0-5300.0) |
Blood eosinophil (%) (n = 172) | 3.6 (1.7-8.0) |
Blood eosinophil (/ul) (n = 168) | 235.0 (130.0-550.0) |
Total IgE, IU/ml (n = 186) | 250.0 (96.1-517.8) |
Comorbidities | Â |
Allergic rhinitis (n = 176) | 135 (76.7%) |
Chronic sinusitis (n = 111) | 34 (30.6%) |
Gastroesophageal reflux (n = 139) | 56 (40.3%) |
Obstruction sleep apnea (n = 96) | 17 (17.7%) |
Anxiety/Depression (n = 104) | 32 (30.8%) |
Vocal cord dysfunction (n = 100) | 33 (33.0%) |
Dysfunctional breathing (n = 98) | 9 (9.2%) |
Asthma-related medications other than ICS/LABA | Â |
LAMA | 39 (17.1%) |
LTRA | 118 (51.8%) |
Theophylline | 54 (23.7%) |
Omalizumab | 80 (35.1%) |
OCS use | 99 (43.4%) |
Bronchial thermoplasty | 3 (1.3%) |