Assessment of clinical relevance of antigen improves diagnostic accuracy of hypersensitivity pneumonitis

BMC Pulmonary Medicine

Table 1 Patient characteristics (n = 172)

Age	64.6 ± 12.4	Diagnostic confidence of HP (ATS/JRS/ALAT-GL)
Male	103 (59.9%)	90%- (Definite)	28 (16.3%)
%FVC (%)	82.3 ± 16.0	70–89% (High + Moderate)	80 (46.5%)
Fibrotic/nonfibrotic	147/25	50–69% (Low)	46 (26.7%)
With exposure (ATS/JRS/ALAT-GL)	167 (97.1%)	-49% (NE)	18 (10.5%)
Exposure grade (EAF)		Diagnostic confidence of HP (Final diagnosis by MDD)
G0/G1/G2/G3/G4	5/63/66/33/5	90%- (Definite)	33 (19.2%)
BALF cell count		70–89% (High)	33 (19.2%)
Lym≧30%, < 30%, NA	36/120/16	50–69% (Low)	13 (7.6%)
HRCT classification (ATS/JRS/ALAT-GL)		-49% (others^a)	93 (54.1%)
Typical/Compatible/Indeterminate	31/113/28
Pathology classification (ATS/JRS/ALAT-GL)
Typical/Probable/Indeterminate/No histopathology	13/81/73/5

ATS/JRS/ALAT-GL American Thoracic Society/Japanese Respiratory Society/Asociación Latinoamericana del Tórax guideline, BALF bronchoalveolar lavage fluid, NA not assessed, HRCT high resolution computed tomography, NE not excluded, MDD multidisciplinary discussion
^aOthers include idiopathic pulmonary fibrosis (n = 2), idiopathic nonspecific interstitial pneumonia (n = 26), collagen vascular disease related interstitial lung disease (n = 4), unclassifiable interstitial lung disease (n = 40), smoking-related interstitial lung disease (n = 8), Idiopathic pleuroparenchymal fibroelastosis (n = 4), lymphoproliferative disease (n = 2), sarcoidosis (n = 2), inflammatory change (n = 1), pulmonary artery infarction (n = 1), chronic eosinophilic pneumonia (n = 1), eosinophilic granulomatosis with polyangiitis (n = 1), and drug-induced interstitial lung disease (n = 1)

ISSN: 1471-2466