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Table 4 Diagnostic performance of modified GL

From: Assessment of clinical relevance of antigen improves diagnostic accuracy of hypersensitivity pneumonitis

 

Sensitivity

Specificity

PPV

NPV

Confidence 90% in ATS/JRS/ALAT-GL

0.58 [0.39–0.75]

0.94 [0.88–0.97]

0.68 [0.48–0.84]

0.90 [0.84–0.95]

Confidence 90% in G2-mGL

0.58 [0.39–0.75]

0.94 [0.89–0.98]

0.70 [0.50–0.86]

0.90 [0.84–0.95]

Confidence 90% in G3-mGL

0.52 [0.34–0.69]

0.95 [0.90–0.98]

0.71 [0.49–0.87]

0.89 [0.83–0.94]

Confidence 90% in G4-mGL

0.36 [0.20–0.55]

0.97 [0.93–0.99]

0.75 [0.48–0.93]

0.87 [0.80–0.92]

Confidence 70% in ATS/JRS/ALAT-GL

0.97 [0.89–1.00]

0.59 [0.49–0.68]

0.59 [0.49–0.69]

0.97 [0.89–1.00]

Confidence 70% in G2-mGL

0.97 [0.89–1.00]

0.67 [0.57–0.76]

0.65 [0.54–0.74]

0.97 [0.90–1.00]

Confidence 70% in G3-mGL

0.96 [0.87–0.99]

0.72 [0.63–0.81]

0.68 [0.57–0.77]

0.96 [0.89–0.99]

Confidence 70% in G4-mGL

0.91 [0.81–0.97]

0.72 [0.63–0.81]

0.67 [0.56–0.76]

0.93 [0.85–0.97]

Confidence 50% in ATS/JRS/ALAT-GL

1.00 [0.93–1.00]

0.19 [0.12–0.29]

0.51 [0.43–0.59]

1.00 [0.74–1.00]

Confidence 50% in G2-mGL

0.99 [0.93–1.00]

0.41 [0.31–0.52]

0.59 [0.50–0.67]

0.97 [0.87–1.00]

Confidence 50% in G3-mGL

0.95 [0.88–0.99]

0.58 [0.47–0.68]

0.66 [0.56–0.74]

0.93 [0.83–0.98]

Confidence 50% in G4-mGL

0.92 [0.84–0.97]

0.61 [0.51–0.71]

0.67 [0.57–0.76]

0.91 [0.80–0.96]

  1. ATS/JRS/ALAT-GL American Thoracic Society/Japanese Respiratory Society/Asociación Latinoamericana del Tórax guideline, PPV positive predictive value, NPV negative predictive value