Table 1 Demographic and clinical characteristics of patients
Variables | Total (n = 744) | Training set (n = 520) | Validation set (n = 224) | P value | statistic |
|---|---|---|---|---|---|
status | 0.999 | 0 | |||
0 | 558 (75) | 390 (75) | 168 (75) | ||
1 | 186 (25) | 130 (25) | 56 (25) | ||
month | 12 (12, 12) | 12 (11.975, 12) | 12 (12, 12) | 0.818 | 58710.5 |
respiratory failure type | 0.883 | 0.022 | |||
1 | 237 (31.855) | 167 (32.115) | 70 (31.25) | ||
2 | 507 (68.145) | 353 (67.885) | 154 (68.75) | ||
Smoking history | 0.950 | 0.004 | |||
0 | 296 (39.785) | 206 (39.615) | 90 (40.179) | ||
1 | 448 (60.215) | 314 (60.385) | 134 (59.821) | ||
Gender | 0.983 | 0 | |||
Male | 487 (65.457) | 341 (65.577) | 146 (65.179) | ||
Female | 257 (34.543) | 179 (34.423) | 78 (34.821) | ||
Hypertension | 0.683 | 0.167 | |||
0 | 455 (61.156) | 321 (61.731) | 134 (59.821) | ||
1 | 289 (38.844) | 199 (38.269) | 90 (40.179) | ||
Diabetes | 0.241 | 1.378 | |||
0 | 639 (85.887) | 441 (84.808) | 198 (88.393) | ||
1 | 105 (14.113) | 79 (15.192) | 26 (11.607) | ||
Cerebrovascular disease | 0.241 | 1.378 | |||
0 | 639 (85.887) | 441 (84.808) | 198 (88.393) | ||
1 | 105 (14.113) | 79 (15.192) | 26 (11.607) | ||
Cardiovascular disease | 0.101 | 2.683 | |||
0 | 592 (79.57) | 405 (77.885) | 187 (83.482) | ||
1 | 152 (20.43) | 115 (22.115) | 37 (16.518) | ||
Chronic bronchitis emphysema | 0.608 | 0.262 | |||
0 | 208 (27.957) | 142 (27.308) | 66 (29.464) | ||
1 | 536 (72.043) | 378 (72.692) | 158 (70.536) | ||
Asthma | 0.999 | 0 | |||
0 | 725 (97.446) | 507 (97.5) | 218 (97.321) | ||
1 | 19 (2.554) | 13 (2.5) | 6 (2.679) | ||
Interstitial lung disease | 0.323 | 0.977 | |||
0 | 702 (94.355) | 494 (95) | 208 (92.857) | ||
1 | 42 (5.645) | 26 (5) | 16 (7.143) | ||
Bronchiectasis | 0.284 | 1.147 | |||
0 | 657 (88.306) | 464 (89.231) | 193 (86.161) | ||
1 | 87 (11.694) | 56 (10.769) | 31 (13.839) | ||
Pneumonia | 0.378 | 0.776 | |||
0 | 575 (77.285) | 407 (78.269) | 168 (75) | ||
1 | 169 (22.715) | 113 (21.731) | 56 (25) | ||
length of stay | 10 (7, 14) | 10 (7.75, 14) | 10 (7, 14) | 0.840 | 58783.5 |
height | 165 (160, 170.25) | 165 (160, 170.25) | 165 (158, 170.25) | 0.839 | 58786.5 |
weight | 60 (50, 70) | 60 (50, 70) | 60 (50, 68.875) | 0.593 | 59675.5 |
age | 74 (66, 80) | 74 (67, 80) | 72.5 (66, 80) | 0.097 | 62699.5 |
VTE score | 3 (1, 4) | 3 (1, 4) | 3 (1, 4) | 0.951 | 58076.5 |
White Blood Cells | 7.85 (5.803, 10.803) | 7.855 (5.803, 10.825) | 7.69 (5.808, 10.498) | 0.742 | 59,126 |
hematocrit | 39.2 (34.95, 43.825) | 39.05 (34.8, 43.5) | 39.3 (35, 44.3) | 0.691 | 57,171 |
red blood cell | 4.34 (3.83, 4.78) | 4.345 (3.828, 4.77) | 4.32 (3.83, 4.802) | 0.964 | 58,362 |
Lymphocyte | 0.92 (0.597, 1.322) | 0.97 (0.61, 1.35) | 0.81 (0.575, 1.223) | 0.027 | 64,193 |
hemoglobin | 130 (116, 145) | 130 (116, 145) | 131 (116, 144) | 0.965 | 58,122 |
platelet | 175.5 (130, 225.25) | 176.5 (130, 228.5) | 172 (128, 223) | 0.442 | 60,310 |
neutrophil | 6.125 (4.175, 9.102) | 6.07 (4.16, 9.203) | 6.33 (4.22, 9.062) | 0.818 | 57,622 |
D- dimer | 0.75 (0.39, 1.632) | 0.78 (0.41, 1.632) | 0.715 (0.338, 1.628) | 0.317 | 60,932 |
fibrinogen | 3.63 (2.74, 4.93) | 3.6 (2.768, 4.84) | 3.66 (2.678, 5.07) | 0.800 | 57557.5 |
Glutamyltransferase | 26.7 (17.65, 44.625) | 25.05 (17, 43.75) | 28 (18.3, 45) | 0.199 | 54,788 |
albumin | 35.408 ± 5.122 | 35.413 ± 5.171 | 35.397 ± 5.019 | 0.970 | 0.038 |
glutamic-pyruvic transaminase | 25 (16, 38) | 24 (16.375, 37) | 25.5 (16, 38) | 0.683 | 57,141 |
triglyceride | 0.97 (0.74, 1.36) | 1.005 (0.74, 1.4) | 0.94 (0.758, 1.232) | 0.342 | 60,797 |
creatinine | 65 (53.175, 80.225) | 65.5 (53.5, 82.275) | 63.95 (52.45, 79.15) | 0.630 | 59536.5 |
creatine kinase | 39 (30, 68) | 39 (30, 66.55) | 41 (30, 70) | 0.346 | 55710.5 |
creatine kinase-MB | 10 (8, 15) | 10 (8, 14) | 10 (8, 17) | 0.158 | 54,465 |
alkaline phosphatase | 78.9 (66, 97.325) | 78.05 (66, 97) | 80.35 (66, 98.25) | 0.541 | 56594.5 |
urea | 6.965 (5.12, 8.995) | 7.035 (5.135, 9.162) | 6.585 (5.092, 8.623) | 0.291 | 61081.5 |
globulin | 28.7 (26, 32) | 28.85 (26, 32.025) | 28.6 (25.85, 31.6) | 0.460 | 60225.5 |
lactic dehydrogenase | 353.5 (214.9, 518) | 360.5 (217.875, 524.25) | 345.5 (207.425, 483) | 0.603 | 59,639 |
aspartate aminotransferase | 26 (20, 36) | 25.1 (20, 35) | 27 (20.325, 37) | 0.189 | 54,709 |
total cholesterol | 4 (3.34, 4.74) | 4 (3.295, 4.72) | 3.985 (3.423, 4.8) | 0.717 | 57266.5 |
total bilirubin | 11.96 (8.398, 17.36) | 11.9 (8.377, 16.9) | 12.345 (8.482, 18.91) | 0.447 | 56,194 |
myoglobin | 38.35 (27.1, 65.55) | 38.65 (28.15, 66.3) | 37.45 (23.8, 64.075) | 0.576 | 59,743 |
N-telencephalic natriuretic peptide | 419 (130, 1920) | 419.29 (130, 1920) | 417.5 (130, 1825) | 0.576 | 59,744 |
PO22 | 41 (38, 44.25) | 41 (38, 44) | 40.5 (37.75, 45) | 0.891 | 57870.5 |
PCO2 | 56 (45, 71) | 56 (44.75, 71) | 57 (46, 73) | 0.304 | 55,475 |
standard bicarbonate | 30.1 (27.3, 33.825) | 30 (27.3, 33.9) | 30.65 (27.275, 33.7) | 0.623 | 56,916 |
methemoglobin | 1.2 (1, 1.3) | 1.2 (1, 1.3) | 1.1 (1, 1.3) | 0.366 | 60656.5 |
reduced hemoglobin | 6.35 (2.7, 10.6) | 6.4 (2.7, 10.6) | 6 (2.775, 10.35) | 0.499 | 60059.5 |
hematokrit | 42 (36, 47) | 42 (36, 47) | 42 (37, 47) | 0.862 | 57772.5 |
base excess | 7 (3.4, 11.625) | 6.9 (3.5, 11.8) | 7.55 (3.3, 11.4) | 0.646 | 57,005 |
lactic acid | 1.5 (1.2, 2) | 1.5 (1.2, 2) | 1.5 (1.2, 1.9) | 0.121 | 62402.5 |
actual bicarbonate | 34 (29.1, 40.325) | 34 (29.175, 39.95) | 34 (29.1, 40.975) | 0.521 | 56,515 |
carboxyhemoglobin | 2.3 (1.8, 2.8) | 2.2 (1.8, 2.725) | 2.3 (1.9, 2.8) | 0.206 | 54,840 |
Blood gas hemoglobin | 13.7 (11.9, 15.125) | 13.8 (11.9, 15.2) | 13.7 (11.9, 15.1) | 0.951 | 58,073 |
oxyhemoglobin saturation | 93.5 (89.075, 97.2) | 93.3 (88.975, 97.2) | 93.8 (89.2, 97.125) | 0.503 | 56,438 |
oxyhemoglobin | 90.3 (86, 93.7) | 90.2 (86, 93.625) | 90.35 (86.275, 93.725) | 0.567 | 56699.5 |
total carbon dioxide | 35.9 (30.5, 42.6) | 35.85 (30.5, 42.2) | 35.95 (30.575, 43.35) | 0.505 | 56448.5 |