Variable | All n = 52 | Sex | Previous pulmonary disease | Mechanical ventilation | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Men n = 32 | Women n = 20 | p-value | Yes n = 15 | No n = 37 | p-value | < 20 days n = 41 | ≥20 days n = 11 | p-value | |||
FVC | % pred | 77.2 (16.6)*** 79.0 [32–114] | 75.2 (15.4)*** 76.2 [34–106] | 80.5 (18.4)*** 81.0 [32–114] | 0.153 | 78.8 (14.7) 77.0 [46–100] | 77.8 (17.5) 79.5 [32–114] | 0.512 | 78.0 (16.0) 79.4 [32–114] | 74.3 (19.2) 78.5 [34–106] | 0.499 |
<LLN, n (%) | 21 (40.5%) | 14 (43.8%) | 7 (35.0%) | 0.575 | 8 (53.3%) | 13 (35.1%) | 0.350 | 16 (39.0%) | 5 (45.5%) | 0.739 | |
FEV1 | % pred | 79.5 (20.7)*** 79.3 [23–121] | 78.3 (18.7)*** 78.7 [33–115] | 81.4 (23.9)** 85.6 [23–121] | 0.301 | 73.8 (22.6) 78.5 [32–103] | 81.8 (19.7) 81–5 [23–121] | 0.499 | 79.4 (19.8) 79.0 [23–121] | 79.8 (24.8 [88.7 [33–115] | 0.327 |
<LLN, n (%) | 15 (28.8%) | 11 (34.4%) | 4 (20.0%) | 0.352 | 6 (40%) | 9 (24%) | 0.318 | 11 (26.8%) | 4 (36.3%) | 0.709 | |
FIVC | % pred | 102.6 (23.4) 106.3 [27–146] | 99.4.1 (22.0) 102.1 [49–146] | 107.7 (25.4)** 113.4 [27–146] | 0.080 | 104.4 (20.0) 102.6 [77–143] | 101.9 (24.8) 106.9 [27–146] | 0.589 | 102.9 (23–1) 107.54 [27–143] | 101.6 (25.5) 102.3 [49–146] | 0.966 |
<LLN, n (%) | 6 (11.5%) | 5 (16.1%) | 1 (5.3) | 0.387 | 1 (6.7%) | 5 (13.5%) | 0.663 | 5 (12.8%) | 1 (9.1%) | 0.737 | |
MIP | % pred | 90.3 (29.3)** 91.2 [16–192] | 97.1 (25.3) 96.9 [43–192] | 79.3 (32.4)* 87.5 [16–149] | 0.060 | 87.5 (31.1) 89.2 [23–149] | 91.4 (28.9) 91.9 [16–192] | 0.607 | 86.7 (30.7) 89.3 [16–192] | 103.7 (18.7) 102.8 [79–149] | 0.607 |
<LLN, n (%) | 14 (26.9) | 6 (18.8) | 8 (40.0) | 0.116 | 6 (40%) | 8 (21.6%) | 0.190 | 14 (34.1) | 0 | 0.025 | |
MEP | % pred | 99.5 (29.6) 99.7 [9–163] | 94.8 (20.0) 94.1 (56–143) | 107.4 (40.2) 113 (9–163) | 0.112 | 98.2 (32.4) 94.5 (57–161] | 100.1 (28.9) 102.1 [9–163] | 0.517 | 97.6 (31.3) 96.0 [9–163] | 106.4 (22.6) 102.1 [81–161] | 0.517 |
<LLN, n (%) | 4 (7.8) | 0 | 4 (20.0) | 0.017 | 2 (13.3%) | 2 (5.4%) | 0.310 | 4 (10.3%) | 0 | 0.563 | |
6MWD§ | % pred | 82.4 (23.6) 85.1 [11–177] | 82.4 (15.5) 81.8 [57–126] | 82.3 (34.0) 85.7 [11–177] | 0.868 | 70.0 (24.8) 73.5 [11–107] | 87.9 (21.2) 87.2 [57–177] | 0.028 | 83.8 (25.2) 87.2 [11–177] | 77.1 (16.0) 70.65 [63–107] | 0.028 |
<LLN,n (%) | 13 (26.5) | 9 (29.0) | 4 (22.2) | 0.743 | 7 (46.7%) | 6 (17.6%) | 0.081 | 9 (23.1%) | 4 (40%) | 0.422 | |
1MSTS | % pred | 68.2 (24.7) 66.7 [13–151] | 71.3 (24.7) 66.7 [29–151] | 63.3 (24.7) 67.6 [13–104] | 0.288 | 62.8 (31.3) 56.8 [29–151] | 70.3 (21.9) 67.6 [13–112] | 0.125 | 70.6 (26.8) 70.6 [13–151] | 59.6 (12.1) 61.4 [41–77] | 0.125 |
<LLN, n (%) | 35 (72.9) | 22 (73.3) | 13 (72.2) | 0.933 | 12 (92.3%) | 23 (66.7%) | 0.081 | 24 (64.8%) | 11 (100%) | 0.023 | |
SaO2a | Difference during 1 min STS-test, % | −2.2 (2.7) −2 [−13–2] | −2,5 (2.98) −2 [−13–2] | −1.8 (2.1) −1 [−5–1] | 0.476 | −2.5 (2.7) − 2 [−8–1} | −1.8 (2.0) − 1.5 [−5–2] | 0.409 | −1.95 (2.2) − 1.0 [−8–2) | − 2.1 (2.2) − 2.0 [− 5–0] | 0.409 |
SaO2 < 92%, n (%) | 9 (18) | 7 (22.5) | 2 (10.5) | 0.452 | 5 (33.3%) | 3 (16.7%) | 0.039 | 6 (14.6%) | 2 (20%) | 0.647 | |
Thoracic expansion | % pred | 63.3 (26.8)*** 58.3 [10–150] | 62.3 (24.9)*** 51.7 [33–150] | 64.7 (30.2)** 60 [10–120] | 0.706 | 58.9 (23.6) 53.3 [10–100] | 65.0 (28.1) 60 [16–150] | 0.612 | 64.9 (27.5) 60.0 [10–150] | 57.1 (24.2) 50.0 [16.-100] | 0.612 |
< 70% of predicted | 32 (67.3) | 21 (65.6) | 11 (55.0) | 0.561 | 9 (60%) | 23 (62.1%) | 0.885 | 25 (61.0%) | 7 (63.6%) | 0.872 |