Skip to main content

Table 1 Patient characteristics according to the sclerostin

From: Higher sclerostin is associated with pulmonary hypertension in pre-dialysis end-stage kidney disease patients: a cross-sectional prospective observational cohort study

Variables

Low Sclerostin

(< 218.18pmol/L)

n = 31

High Sclerostin

(≥ 218.18pmol/L)

n = 13

P

Male

18(58.1%)

11(84.6%)

0.08

Age

52.2 ± 16.2

57.6 ± 13.7

0.22

Diabetes mellitus

11(35.5%)

8(61.5%)

0.10

Hypertension

28 (90.3%)

13(100%)

0.34

Coronary artery disease

25 (80.6%)

10 (76.9%)

0.54

BMI (kg/m2)

24.7 ± 4.3

26.7 ± 3.6

0.08

BSA (m2)

1.7 ± 0.2

1.7 ± 0.2

0.15

Baseline PWV (per 10 cm/min)

1719.3 ± 456

1688.5 ± 362.4

0.42

SBP (mmHg)

140 [110–170]

135 [110–152]

0.26

DBP (mmHg)

80[66–115]

80[70–100]

0.27

iPTH (pg/mL) [15–80]

204.6 ± 128.0

261.1 ± 186.3

0.13

25-OH-Vit.D (ng/mL)

[20–40]

7.0 ± 5.6

5.1 ± 2.9

0.13

Hb (g/dL) [11–16]

9.2 ± 1.9

9.2 ± 0.8

0.47

Total CO2 (mg/dL) [23–29]

19.7 ± 6.6

20.4 ± 5.2

0.38

Albumin (mg/dL) [3.4–5.4]

3.4 ± 0.4

3.3 ± 0.6

0.32

ALP (U/L)[44–147]

89.7 ± 34.0

78.4 ± 21.4

0.14

Ca (mg/dL) [8.6–10.3]

7.5 ± 1.2

8.0 ± 0.8

0.09

P (mg/dL) [2.5–4.5]

5.3 ± 2.5

5.0 ± 1.6

0.33

Total Cholesterol (mg/dL) [< 200]

149.1 ± 45.7

133.2 ± 37.3

0.14

LDL (mg/dL) [< 160]

90.8 ± 34.8

81.8 ± 25.2

0.20

CRP (mg/dL) [< 0.3]

81.6 ± 11.8

99.8 ± 15.6

0.34

Creatinine (mg/dL)[0.7–1.3]

10.2 ± 4.9

8.5 ± 4.2

0.14

eGFR (ml/min/1.73m2)

5.6 ± 2.5

6.8 ± 3.0

0.17

Vascular calcification more than one site (SVCS ≥ 1)

23(74.2%)

10(76.9%)

0.59

SVCS ≥ 3

6 (19.4%)

2 (15.4%)

0.56

  1. Abbreviations BMI, body mass index; BSA, body surface area; PWV, pulse wave velocity; SBP, systolic blood pressure; DBP, diastolic blood pressure; Hb, hemoglobin; ALP, alkaline phosphatase; LDL, low density lipoprotein; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate using CKD-EPI equation