Variables | Low Sclerostin (< 218.18pmol/L) n = 31 | High Sclerostin (≥ 218.18pmol/L) n = 13 | P |
---|---|---|---|
Male | 18(58.1%) | 11(84.6%) | 0.08 |
Age | 52.2 ± 16.2 | 57.6 ± 13.7 | 0.22 |
Diabetes mellitus | 11(35.5%) | 8(61.5%) | 0.10 |
Hypertension | 28 (90.3%) | 13(100%) | 0.34 |
Coronary artery disease | 25 (80.6%) | 10 (76.9%) | 0.54 |
BMI (kg/m2) | 24.7 ± 4.3 | 26.7 ± 3.6 | 0.08 |
BSA (m2) | 1.7 ± 0.2 | 1.7 ± 0.2 | 0.15 |
Baseline PWV (per 10 cm/min) | 1719.3 ± 456 | 1688.5 ± 362.4 | 0.42 |
SBP (mmHg) | 140 [110–170] | 135 [110–152] | 0.26 |
DBP (mmHg) | 80[66–115] | 80[70–100] | 0.27 |
iPTH (pg/mL) [15–80] | 204.6 ± 128.0 | 261.1 ± 186.3 | 0.13 |
25-OH-Vit.D (ng/mL) [20–40] | 7.0 ± 5.6 | 5.1 ± 2.9 | 0.13 |
Hb (g/dL) [11–16] | 9.2 ± 1.9 | 9.2 ± 0.8 | 0.47 |
Total CO2 (mg/dL) [23–29] | 19.7 ± 6.6 | 20.4 ± 5.2 | 0.38 |
Albumin (mg/dL) [3.4–5.4] | 3.4 ± 0.4 | 3.3 ± 0.6 | 0.32 |
ALP (U/L)[44–147] | 89.7 ± 34.0 | 78.4 ± 21.4 | 0.14 |
Ca (mg/dL) [8.6–10.3] | 7.5 ± 1.2 | 8.0 ± 0.8 | 0.09 |
P (mg/dL) [2.5–4.5] | 5.3 ± 2.5 | 5.0 ± 1.6 | 0.33 |
Total Cholesterol (mg/dL) [< 200] | 149.1 ± 45.7 | 133.2 ± 37.3 | 0.14 |
LDL (mg/dL) [< 160] | 90.8 ± 34.8 | 81.8 ± 25.2 | 0.20 |
CRP (mg/dL) [< 0.3] | 81.6 ± 11.8 | 99.8 ± 15.6 | 0.34 |
Creatinine (mg/dL)[0.7–1.3] | 10.2 ± 4.9 | 8.5 ± 4.2 | 0.14 |
eGFR (ml/min/1.73m2) | 5.6 ± 2.5 | 6.8 ± 3.0 | 0.17 |
Vascular calcification more than one site (SVCS ≥ 1) | 23(74.2%) | 10(76.9%) | 0.59 |
SVCS ≥ 3 | 6 (19.4%) | 2 (15.4%) | 0.56 |