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TableĀ 2 Characteristics of the clinical data of the hypothyroidism group and the euthyroid group of patients with OSA, using 60Ā years of age as a cutoff

From: The association of lymphocyte with hypothyroidism in obstructive sleep apnea

Ā 

Ageļ¼œ60(n=771)

Ageā‰„60(n=149)

Ā 

Euthyroid

Hypothyroidism

P

Euthyroid

Hypothyroidism

P

Participant

736.00(95.46%)

35.00(4.54%)

-

143.00(95.97%)

6.00(4.03%)

-

Age

39.26Ā±10.32

37.83Ā±11.22

0.426

66.83Ā±5.38

63.83Ā±2.40

0.177

BMI

33.09Ā±8.05

36.00Ā±9.15

0.038

28.71Ā±4.86

27.67Ā±2.47

0.606

NC

42.17Ā±5.26

41.89Ā±4.19

0.756

40.34Ā±3.89

39.83Ā±2.99

0.752

WC

108.96Ā±16.83

113.24Ā±18.16

0.143

103.86Ā±12.89

99.00Ā±6.23

0.361

ESS

6.00(3.00ļ¼Œ12.00)

10.00(4.00ļ¼Œ14.00)

0.028

8.00(4.00ļ¼Œ13.00)

11.00(9.25ļ¼Œ15.50)

0.143

AHI

46.40(21.63ļ¼Œ72.18)

39.60(12.50ļ¼Œ78.70)

0.682

42.10(19.90ļ¼Œ65.20)

47.00(30.63ļ¼Œ62.45)

0.674

ODI

38.25(17.20ļ¼Œ68.53)

36.00(14.50ļ¼Œ68.40)

0.875

36.50(14.30ļ¼Œ54.90)

41.60(28.53ļ¼Œ57.33)

0.395

ArI

24.20(13.40ļ¼Œ45.48)

23.90(12.80ļ¼Œ50.90)

0.775

20.60(12.00ļ¼Œ35.50)

27.15(11.83ļ¼Œ39.78)

0.746

meanSpO2

94.00(92.00ļ¼Œ96.00)

94.00(90.00ļ¼Œ95.00)

0.418

94.00(92.00ļ¼Œ95.00)

93.00(91.75ļ¼Œ95.00)

0.822

miniSpO2

78.00(65.00ļ¼Œ85.00)

76.00(60.00ļ¼Œ86.00)

0.366

78.00(71.00ļ¼Œ85.00)

69.00(61.00ļ¼Œ75.00)

0.051

T90

4.70(0.30ļ¼Œ24.78)

3.90(0.30ļ¼Œ35.90)

0.841

6.50(0.60ļ¼Œ21.20)

16.40(3.48ļ¼Œ26.93)

0.281

FT3

4.54(4.21ļ¼Œ4.95)

4.36(4.05ļ¼Œ4.90)

0.158

4.23(3.88ļ¼Œ4.61)

4.46(4.20ļ¼Œ4.76)

0.257

FT4

12.40(11.54ļ¼Œ13.37)

11.91(10.90ļ¼Œ13.45)

0.096

12.18(11.38ļ¼Œ13.45)

11.90(10.29ļ¼Œ13.49)

0.481

TSH

1.88(1.31ļ¼Œ2.58)

5.78(5.21ļ¼Œ7.39)

<0.001

1.79(1.30ļ¼Œ2.38)

6.60(5.63ļ¼Œ10.14)

<0.001

WBC#(Ɨ10*9/L)

6.84(5.72ļ¼Œ8.14)

7.51(6.02ļ¼Œ8.88)

0.131

6.51(5.23ļ¼Œ8.02)

6.56(5.61ļ¼Œ7.81)

0.862

RBC#(Ɨ10*12/L)

4.95(4.61ļ¼Œ5.29)

4.86(4.64ļ¼Œ5.26)

0.448

4.49(4.17ļ¼Œ4.83)

4.45(4.18ļ¼Œ5.06)

0.798

HGB(g/L)

148.00(135.25ļ¼Œ158.00)

144.00(126.00ļ¼Œ155.00)

0.065

138.00(128.00ļ¼Œ148.00)

138.50(127.25ļ¼Œ156.25)

0.615

PLT#(Ɨ10*9/L)

250.00(216.25ļ¼Œ293.00)

253.00(215.00ļ¼Œ297.00)

0.437

215.00(170.00ļ¼Œ253.00)

235.00(188.00ļ¼Œ261.00)

0.579

NEU%

55.60(50.30ļ¼Œ61.30)

54.50(49.30ļ¼Œ60.90)

0.446

59.60(53.60ļ¼Œ65.90)

53.85(47.10ļ¼Œ59.85)

0.087

LYMPH%

33.45(28.53ļ¼Œ38.60)

36.00(31.40ļ¼Œ39.20)

0.128

29.20(22.70ļ¼Œ35.90)

36.10(29.53ļ¼Œ41.35)

0.061

MON%

7.40(6.40ļ¼Œ8.60)

7.20(6.00ļ¼Œ8.00)

0.072

7.90(6.70ļ¼Œ8.90)

8.10(6.70ļ¼Œ9.73)

0.657

EOS%

2.20(1.50ļ¼Œ3.40)

1.80(1.30ļ¼Œ2.60)

0.079

2.00(1.20ļ¼Œ3.00)

1.40(1.00ļ¼Œ2.43)

0.359

BAS%

0.50(0.40ļ¼Œ0.70)

0.50(0.40ļ¼Œ0.70)

0.973

0.50(0.30ļ¼Œ0.60)

0.55(0.30ļ¼Œ0.88)

0.477

NEU#(Ɨ10*9/L)

3.73(3.00ļ¼Œ4.79)

3.86(3.03ļ¼Œ4.55)

0.745

3.87(3.00ļ¼Œ4.95)

3.55(2.94ļ¼Œ4.15)

0.451

LYMPH#(Ɨ10*9/L)

2.22(1.83ļ¼Œ2.67)

2.64(2.03ļ¼Œ3.00)

0.011

1.83(1.34ļ¼Œ2.35)

2.51(1.91ļ¼Œ2.93)

0.055

MON#(Ɨ10*9/L)

0.50(0.42ļ¼Œ0.60)

0.53(0.42ļ¼Œ0.60)

0.890

0.49(0.41ļ¼Œ0.60)

0.56(0.44ļ¼Œ0.64)

0.374

EOS#(Ɨ10*9/L)

0.15(0.10ļ¼Œ0.24)

0.15(0.09ļ¼Œ0.18)

0.242

0.13(0.07ļ¼Œ0.19)

0.09(0.06ļ¼Œ0.16)

0.351

BAS#(Ɨ10*9/L)

0.04(0.03ļ¼Œ0.05)

0.04(0.03ļ¼Œ0.05)

0.496

0.03(0.02ļ¼Œ0.04)

0.04(0.02ļ¼Œ0.05)

0.330

  1. Euthyroid indicates that FT3, FT4 and TSH levels are in the normal range. Hypothyroidism included newly diagnosed overt hypothyroidism and newly diagnosed subclinical hypothyroidism. BMI body mass index, NC neck circumference, WC waist circumference, ESS Epworth sleepiness scale, AHI apnea hypopnea index, ODI oxygen desaturation index, Arl arousal index, meanSpO2 mean percutaneous oxygen saturation, minSpo2 minimum percutaneous oxygen saturation, T90 proportion of cumulative sleep time with SpO2 below 90% in total sleep time, FT3 free triiodotironine, FT4 free thyroxine, TSH thyroid stimulating hormone, WBC# white blood cell count, RBC# red blood cell, HGB hemoglobin level, PLT# platelet count, NEU% neuthrophil percentage, LYMPH% lymphocyte percentage, MON% monocyte percentage, EOS% eosinophil cell percentage, BAS% basophil cell percentage, NEU# neutrophil count, LYMPH# lymphocyte count, MON# monocyte count, EOS# eosinophil cell count, BAS# basophil cell count