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TableĀ 3 Characteristics of the clinical data of the hypothyroidism group and the euthyroid group of patients with OSA, using AHI as a cutoff

From: The association of lymphocyte with hypothyroidism in obstructive sleep apnea

Ā 

AHIā€‰ā‰¤ā€‰30 (nā€‰=ā€‰328)

AHIā€‰>ā€‰30 (nā€‰=ā€‰592)

Ā 

Euthyroid

Hypothyroidism

P

Euthyroid

Hypothyroidism

P

Participant

313.00(95.43%)

15.00(4.57%)

-

566.00(95.61%)

26.00(4.39%)

-

Age

42.17ā€‰Ā±ā€‰14.80

34.27ā€‰Ā±ā€‰12.61

0.043

44.61ā€‰Ā±ā€‰13.57

45.88ā€‰Ā±ā€‰13.05

0.640

BMI

31.22ā€‰Ā±ā€‰7.66

35.48ā€‰Ā±ā€‰6.48

0.035

33.02ā€‰Ā±ā€‰7.79

34.38ā€‰Ā±ā€‰10.26

0.508

NC

40.10ā€‰Ā±ā€‰3.67

40.60ā€‰Ā±ā€‰3.18

0.602

42.85ā€‰Ā±ā€‰5.51

42.15ā€‰Ā±ā€‰4.47

0.526

WC

103.81ā€‰Ā±ā€‰16.02

109.23ā€‰Ā±ā€‰14.80

0.200

110.52ā€‰Ā±ā€‰16.06

112.27ā€‰Ā±ā€‰19.27

0.591

ESS

5.00(2.00, 8.00)

6.00(3.00, 10.00)

0.496

8.00(4.00, 14.00)

12.00(10.00, 15.25)

0.006

AHI

16.90(10.80, 23.25)

12.30(8.70, 17.40)

0.100

65.75(47.05, 79.28)

64.20(40.88, 85.15)

0.669

ODI

12.40(7.60, 18.35)

14.20(8.20, 19.00)

0.751

58.65(39.83, 75.65)

54.55(35.93, 78.30)

0.965

ArI

12.10(8.10, 17.75)

12.80(7.90, 16.00)

0.616

36.40(21.78, 54.15)

36.40(23.73, 61.00)

0.766

meanSpO2

96.00(95.00, 96.00)

95.00(94.00, 96.00)

0.275

93.00(90.00, 94.00)

92.00(89.75, 94.25)

0.617

miniSpO2

85.00(82.00, 89.00)

86.00(80.00, 87.00)

0.272

71.00(59.75, 79.00)

66.00(52.25, 73.75)

0.069

T90

0.10(0.00, 1.10)

0.40(0.00, 1.50)

0.500

14.65(4.68, 37.73)

19.50(4.35, 36.85)

0.747

FT3

4.44(4.11, 4.82)

4.48(4.06, 4.99)

0.970

4.54(4.17, 4.95)

4.39(4.02, 4.76)

0.256

FT4

12.25(11.41, 13.38)

12.02(11.31, 13.46)

0.706

12.42(11.55, 13.39)

11.64(10.80, 13.12)

0.050

TSH

1.90(1.34, 2.59)

5.36(5.21, 5.97)

ā€‰<ā€‰0.001

1.85(1.30, 2.52)

6.31(5.35, 7.97)

ā€‰<ā€‰0.001

WBC#(Ɨā€‰10*9/L)

6.62(5.38, 8.20)

7.72(6.29, 9.41)

0.054

6.85(5.76, 8.05)

7.34(5.89, 8.11)

0.734

RBC#(Ɨā€‰10*12/L)

4.70(4.42, 5.07)

4.79(4.52, 4.94)

0.883

4.97(4.63, 5.30)

4.91(4.53, 5.31)

0.629

HGB(g/L)

140.00(130.00, 151.00)

134.00(122.00, 150.00)

0.407

149.00(137.00, 158.00)

146.00(127.50, 155.50)

0.209

PLT#(Ɨā€‰10*9/L)

245.00(212.00, 293.00)

296.00(253.00, 319.00)

0.019

245.00(210.00, 283.25)

243.00(208.25, 262.00)

0.517

NEU%

55.90(50.85, 61.90)

54.00(48.10, 62.30)

0.391

56.25(50.68, 62.50)

55.00(49.50, 59.75)

0.272

LYMPH%

33.80(28.65, 37.60)

36.50(28.10, 42.00)

0.197

32.55(27.20, 38.33)

35.25(31.70, 37.88)

0.087

MON%

7.40(6.20, 8.60)

7.20(6.40, 8.40)

0.746

7.60(6.60, 8.70)

7.35(5.75, 7.93)

0.039

EOS%

2.00(1.30, 3.25)

1.60(1.20, 2.20)

0.157

2.20(1.50, 3.30)

1.85(1.30, 2.70)

0.180

BAS%

0.50(0.40, 0.60)

0.50(0.30, 0.60)

0.761

0.50(0.40, 0.70)

0.55(0.48, 0.73)

0.568

NEU#(Ɨā€‰10*9/L)

3.74(2.90, 4.77)

3.86(3.42, 4.66)

0.380

3.78(3.05, 4.84)

3.89(2.75, 4.37)

0.501

LYMPH#(Ɨā€‰10*9/L)

2.13(1.76, 2.64)

2.64(2.31, 3.00)

0.007

2.19(1.73, 2.65)

2.47(2.00, 3.01)

0.075

MON#(Ɨā€‰10*9/L)

0.49(0.40, 0.59)

0.58(0.50, 0.67)

0.014

0.51(0.43, 0.61)

0.49(0.39, 0.59)

0.186

EOS#(Ɨā€‰10*9/L)

0.14(0.09, 0.22)

0.12(0.09, 0.16)

0.569

0.15(0.10, 0.24)

0.15(0.07, 0.19)

0.236

BAS#(Ɨā€‰10*9/L)

0.03(0.02, 0.05)

0.03(0.02, 0.05)

0.620

0.04(0.03, 0.05)

0.04(0.03, 0.05)

0.332

  1. Euthyroid indicates that FT3, FT4 and TSH levels are in the normal range. Hypothyroidism included newly diagnosed overt hypothyroidism and newly diagnosed subclinical hypothyroidism. BMI body mass index, NC neck circumference, WC waist circumference, ESS Epworth sleepiness scale, AHI apnea hypopnea index, ODI oxygen desaturation index, ArI arousal index, meanSpO2 mean percutaneous oxygen saturation, minSpO2 minimum percutaneous oxygen saturation, T90 proportion of cumulative sleep time with SpO2 below 90% in total sleep time, FT3 free triiodotironine, FT4 free thyroxine, TSH thyroid stimulating hormone, WBC# white blood cell count, RBC# red blood cell count, HGB hemoglobin level, PLT# platelet count, NEU% neutrophil percentage, LYMPH% lymphocyte percentage, MON% monocyte percentage, EOS% eosinophil cell percentage, BAS% basophil cell percentage, NEU# neutrophil count, LYMPH# lymphocyte count, MON# monocyte count, EOS# eosinophil cell count, BAS# basophil cell count