Table 5 Clinical Data in different groups

Nicotine usage, n (%)

30(69.8)

14(93.3)

10(62.5)

5(83.3)

Never

13

1

6

1

Current

27

12

8

5

Former

3

2

2

0

Missing

9

2

10

1

Number of cigarette years, mean ± SD (n)

397.26 ± 442.86

665.33 ± 356.74*

283.31 ± 279.80

405 ± 305.53

Vital signs before 6 MW, mean ± SD

Resting state SBP(Millimetre of mercury)mean ± SD

114.29 ± 15.93

118.53 ± 18.31

118.38 ± 30.48

127.25 ± 19.87

Resting state DBP(Millimetre of mercury)mean ± SD

73.77 ± 11.66

79.06 ± 14.74

76.64 ± 12.93

73 ± 3.92

Oxygen saturation (%), mean ± SD

95.37 ± 1.83

95.58 ± 1.44

95.79 ± 1.78

95.5 ± 1.52

Heart Rate

74.93 ± 10.43

80.85 ± 14.71

72.63 ± 10.15

80.17 ± 9.54

6MWD(m), mean ± SD

371.33 ± 62.44

351.05 ± 62.48

375.67 ± 59.89

370.83 ± 71.69

Vital signs after 6 MW, mean ± SD

Resting state SBP(mmHg), mean ± SD

124.48 ± 14.39

129.50 ± 16.45

129.00 ± 13.33

134 ± 11.79

Resting state DBP(mmHg), mean ± SD

74.36 ± 9.02

78.30 ± 12.30

76.57 ± 9.31

73.67 ± 12.06

Oxygen saturation (%), mean ± SD

93.74 ± 3.31

93.67 ± 2.43

94.44 ± 2.44

94.5 ± 2.07

Heart Rate

86.10 ± 21.19

98.42 ± 16.11*

89.93 ± 15.31

91.5 ± 11.18*

Spirometry test, mean ± SD (n)

FVC(L)

2.93 ± 0.97

2.75 ± 0.89

3.09 ± 0.93

3.09 ± 1.20

FEV1 (L)

1.71 ± 0.64

1.5 ± 0.72

1.83 ± 0.64

2.14 ± 0.93

FEV1% predicted

65.71 ± 18.38

58.24 ± 27.28*

77.95 ± 20.61

75.51 ± 16.30

FEV1/FVC ratio (%)

57.15 ± 7.41

52.08 ± 11.75*

89.85 ± 11.50

73.52 ± 7.45*

PEF (L/min)

4.61 ± 1.96

4.48 ± 1.74

4.59 ± 1.79

5.56 ± 2.99

MMEF75/25

0.77 ± 0.38

0.7 ± 0.46

1.00 ± 0.576

1.14 ± 0.72

CAT total score, mean ± SD

8.5 ± 4.23

8 ± 6

3.5 ± 7.78

5 ± 6.48

mMRC grade, mean ± SD

1.67 ± 0.69

0.5 ± 0.5

0.5 ± 0.71

0.5 ± 0.82

CCQ score, mean ± SD

7.33 ± 6.55

15 ± 10

5.5 ± 2.12

9 ± 2.12

PAD evaluation index

Left ABI

1.13 ± 0.06

0.7 ± 0.1

1.13 ± 0.07

0.83 ± 0.15

Right ABI

1.16 ± 0.09

0.7 ± 0.11

1.16 ± 0.08

0.89 ± 0.10

Left TBI

0.87 ± 0.07

0.61 ± 0.08

0.91 ± 0.11

0.67 ± 0.20

Right TBI

0.82 ± 0.06

0.69 ± 0.19

0.84 ± 0.12

0.64 ± 0.10

PAS evaluation index

Left baPWV (cm/s)

1333.48 ± 308.33

1680.41 ± 537.57

1311.89 ± 507.62

1543.29 ± 214.63

Right baPWV (cm/s)

1321.19 ± 293.30

1657.24 ± 495.33

1367.20 ± 411.85

1511.43 ± 219.74