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Fig. 8 | BMC Pulmonary Medicine

Fig. 8

From: Cuproptosis-related ceRNA axis triggers cell proliferation and cell cycle through CBX2 in lung adenocarcinoma

Fig. 8

LncRNA-AC144450.1, as the ceRNA of miR-424-5p, regulated the CBX2 protein and affected the malignant progression of lung cancer. (A) Predicted binding site between miR-424-5p and lncRNA-AC144450.1. (B) Luciferase assays were performed to test the effect of miR-424-5p on wild-type or. mutant lncRNA-AC144450.1 after treating with miR-424-5p mimic. (C) Venn diagram showed the overlapping genes of lncRNA-AC144450.1 groups and miR-424-5p groups. (D) Pathway enrichment of genes co-regulated by lncRNA-AC144450.1 and miR-424-5p. (E) The CCK8 results of A549 cells with knockdown AC144450.1 treated with NC inhibitor or miR-424-5p inhibitor. (F) The clone formation results of A549 cells with knockdown AC144450.1 treated with NC inhibitor or miR-424-5p inhibitor

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BMC Pulmonary Medicine

ISSN: 1471-2466

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