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Table 2 Pulmonary function test results of patients before and after systemic chemotherapy

From: Understanding changes in pulmonary function and functional status in breast cancer patients after systemic chemotherapy and radiotherapy: a prospective study

 

Mean (SD)

    

n = 25

cT0

cT1

Mean difference (SD)

95% CI

t

p

FVC

2.96 ± 0.63

2.83 ± 0.58

0.13 ± 0.28

0.015/0.25

2.338

0.028

FEV1

2.39 ± 0.40

2.28 ± 0.45

0.11 ± 0.20

0.02/0.19

2.708

0.012

FEV/FVC

81.76 ± 7.01

81.14 ± 6.23

0.62 ± 5.60

-1.69/2.92

0.550

0.587

PEF

4.48 ± 0.86

4.46 ± 1.24

0.0008 ± 1.03

− 0.41/0.44

0.042

0.967

FEF_25–75

2.50 ± 0.55

2.30 ± 0.58

0.19 ± 0.45

0.012/0.38

2.200

0.038

FVC % (pred)

87.44 ± 13.55

84.12 ± 14.45

3.32 ± 8.37

− 0.13 ± 6.78

1.982

0.059

FEV1% (pred)

88.12 ± 11.84

84.68 ± 14.71

3.44 ± 7.09

0.51/6.37

2.424

0.023

FEV/FVC % (pred)

101.12 ± 9.51

100.4 ± 8.14

0.72 ± 6.97

-2.15/3.59

0.517

0.610

FEF_25–75% (pred)

94.20 ± 25.77

86.60 ± 23.05

7.60 ± 19.15

− 0.30/15.50

1.984

0.059

MIP

68.86 ± 19.16

65.48 ± 18.27

3.38 ± 11.85

-2.01/8.77

1.307

0.206

MIP % (pred)

86.62 ± 24.11

83.67 ± 22.06

2.95 ± 15.25

-3.99/9.89

0.887

0.386

MEP

74.21 ± 20.61

74.26 ± 24.59

− 0.04 ± 16.62

-7.23/7.14

-0.013

0.990

MEP % (pred)

80.17 ± 20.45

84.65 ± 24.11

-4.48 ± 23.48

-14.63/5.67

-0.915

0.370

  1. FVC: Forced vital capacity, FEV1: Forced expiratory volume in 1s, PEF: Peak expiratory flow, FEF 25–75: Forced expiratory flow of between 25% and 75% of vital capacity, Pred: Predicted, MIP: Maximal Inspiratory pressure, MEP: Maximal expiratory pressure, SD: Standard deviation, cT0: Before chemotherapy, cT1: After chemotherapy, p <.05., t: Paired samples t-test, CI: Confidence interval
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BMC Pulmonary Medicine

ISSN: 1471-2466

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