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Table 3 Pulmonary function test results of patients before and after systemic chemotherapy and radiotherapy

From: Understanding changes in pulmonary function and functional status in breast cancer patients after systemic chemotherapy and radiotherapy: a prospective study

 

Mean (SD)

   

n = 15

cT0

cT1

rT1

F

p

ηp2

FVC

3.07 ±.55a

2.93 ± 0.49

2.90 ±.54a

4.840

0.016

0.25

FEV1

2.48 ±.38a

2.37 ± 0.39

2.33 ±.41a

7.815

0.002

0.36

FEV/FVC

81.28 ± 0.4.50

81.07 ± 4.82

80.56 ± 4.60

0.188

0.811

0.013

PEF

4.71 ± 0.86

4.85 ± 1.18

4.50 ± 0.80

1.447

0.25

0.09

FEF_25–75

2.59 ± 0.53

2.43 ± 0.55

2.39 ± 0.57

2.770

0.087

0.16

FVC % (pred)

88.93 ± 10.50a,b

85.20 ± 10.03a

84.33 ± 10.42b

4.145

0.027

0.23

FEV1% (pred)

89.00 ± 9.41a

85.40 ± 9.83

84.07 ± 10.40a

6.372

0.006

0.31

FEV/FVC % (pred)

100.06 ± 5.97

99.87 ± 5.68

99.40 ± 5.46

0.105

0.885

0.007

FEF_25–75% (pred)

93.06 ± 21.28

86.80 ± 16.63

85.80 ± 17.16

2.344

0.123

0.14

MIP

68.57 ± 17.67

64.69 ± 18.70

66.73 ± 18.44

0.669

0.506

0.05

MIP % (pred)

84.50 ± 22.63

82.30 ± 20.86

83.20 ± 22.34

0.343

0.68

0.028

MEP

71.35 ± 18.39

69.86 ± 24.92

71.47 ± 23.81

0.217

0.768

0.016

MEP % (pred)

75.71 ± 18.95

80.64 ± 25.39

80.33 ± 19.75

0.463

0.596

0.034

  1. FVC: Forced vital capacity, FEV1: Forced expiratory volume in 1s, PEF: Peak expiratory flow, FEF 25–75: Forced expiratory flow of between 25% and 75% of vital capacity, Pred: Predicted, MIP: Maximal Inspiratory pressure, MEP: Maximal expiratory pressure, SD: Standard deviation, p <.05, ηp2: Partial eta-squared, F: Repeated Measures ANOVA, cT0: Before chemotherapy, cT1: After chemotherapy, rT1: After radiotherapy
  2. aSignificantly different between two measurement times according to the Bonferroni Post-hoc test
  3. bSignificantly different between two measurement times according to the Bonferroni Post-hoc test