Causal associations between gut microbiota, metabolites and asthma: a two-sample Mendelian randomization study

BMC Pulmonary Medicine

Table 3 MR results of causal links between eosinophilic asthma and Indolepropionate

Exposure	Outcome	Method	Nsnp	Beta	SE	p	Heterogeneity		Horizontal pleiotropy
							Q	p	Intercept	SE	p
Eosinophilic asthma	Indolepropionate	IVW	15	−8.94 × 10⁻³	4.31 × 10⁻³	0.04	6.91	0.91	3.40 × 10⁻⁴	5.90 × 10⁻³	0.96
Eosinophilic asthma	Indolepropionate	MR Egger	15	−1.01 × 10⁻²	2.14 × 10⁻²	0.64	6.92	0.94
Eosinophilic asthma	Indolepropionate	Maximum likelihood	15	−9.00 × 10⁻³	4.36 × 10⁻³	0.04
Eosinophilic asthma	Indolepropionate	Weighted median	15	−9.78 × 10⁻³	5.63 × 10⁻³	0.08
Eosinophilic asthma	Indolepropionate	Weighted mode	15	−7.33 × 10⁻³	8.03 × 10⁻³	0.38

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