Table 1 Demographics and characteristics of patients
Characteristic | PG(n = 53) | CG(n = 91) | P |
|---|---|---|---|
Age, years, mean (SD) | 56.2(10.4) | 56.2(8.0) | 0.98 |
Gender | 0.49 | ||
Male | 20(37.7%) | 40(44.0%) | |
Female | 33(62.3%) | 51(56.0%) | |
Smoking Status | 0.43 | ||
Never | 37(69.8%) | 70(76.9%) | |
Current/former | 16(30.2%) | 21(23.1%) | |
ECOG Score | 0.60 | ||
0 | 19(35.8%) | 38(41.8%) | |
1 | 34(64.2%) | 53(58.2%) | |
EGFR mutation | 0.60 | ||
Exon 19 del | 30(56.6%) | 56(61.5%) | |
Exon 21 L858R | 23(43.4%) | 35(38.5%) | |
The therapy modes of TKIs | 0.07 | ||
Only 1 or 2-generation TKIs | 13(24.5%) | 20(22.0%) | |
Only 3rd-generation TKIs | 16(30.2%) | 14(15.4%) | |
Sequential EGFR-TKIs | 24(45.3%) | 57(62.6%) | |
Location of Metastases | |||
Brain | 22(41.5%) | 25(27.5%) | 0.10 |
Liver | 12(22.6%) | 11(12.1%) | 0.11 |
Bone | 29(54.7%) | 48(52.7%) | 0.86 |