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Table 1 Demographics and clinical characteristics of patients with and without p-SAD

From: Identification and treatment of persistent small airway dysfunction in paediatric patients with asthma: a retrospective cohort study

Item

Asthma without p-SAD (n = 167)

Asthma with p-SAD (n = 81)

Z/χ2

P

Age of receiving the regular treatment (years old)

7.00(6.00,8.50)

7.50(6.50,9.00)

-1.837

0.067

Male

111(66.5)

55(67.9)

0.051

0.822

BMI (kg/m2)

16.50(15.20,17.80)

16.90(14.95,18.90)

-0.061

0.951

Birth weight (kg)

3.20(3.00,3.40)

3.20(3.00,3.45)

0

1

Breastfeeding (months)

7.00(3.00,11.00)

6.00(4.50,10.00)

-0.538

0.591

History of antibiotic usage in the first year

50(29.9)

25(30.8)

0.022

0.882

History of passive smoking

38(22.8)

29(35.8)

4.71

0.03

Family history of asthma

25(15.0)

20(24.7)

3.471

0.062

Allergens

119(71.3)

55(67.9)

0.293

0.588

Allergic rhinitis

138(82.6)

64(79.0)

0.474

0.491

Eczema

37(22.2)

15(18.5)

0.435

0.509

Asthma control

    

Well-controlled

155(92.81)

64(79.01)

10.062

0.002

Partly-controlled

12(7.19)

17(20.99)

  

Time taken for asthma to reach well controlled (years)

1.00(1.00,1.00)

1.00(1.00,2.00)

-1.002

0.316

Age at the time of onset of suspected asthma symptoms (years old)

6.00(4.50,7.00)

5.00(3.50,7.00)

-1.989

0.047

Duration of asthma (years)

3.50(3.00,5.00)

4.50(3.00,7.25)

-2.688

0.007

Age at which the diagnosis of asthma was made (years old)

6.50(6.00,8.00)

7.00(5.75,8.25)

-0.143

0.886

Duration of using ICS or ICS/LABA (years)

2.50(2.00,3.00)

3.00(2.00,3.50)

-3.724

< 0.001

  1. Data were presented as median (25%, 75% IQR) or number (%); the difference between groups was analyzed by Mann-Whitney U-test or chi-squared test. BMI, body mass index; p-SAD, persistent small airway dysfunction; ICS, inhaled corticosteroids; LABA, long-acting beta-agonist