Table 2 Clinical characteristics of subjects with eosinophilic bronchiectasis or non-eosinophilic bronchiectasis after propensity score matching
Non-Eos | Eos | ||
|---|---|---|---|
N = 156 | N = 156 | P-value | |
Body mass index, kg/m2 | 20.4 [18.3, 23.4] | 20.8 [18.2, 24.0] | 0.767 |
Smoking status, n (%) | |||
Never-smokers | 116 (74.4) | 114 (73.1) | 0.726 |
Ex-smokers | 25 (16.0) | 27 (17.3) | 0.658 |
Current Smokers | 15 (9.6) | 15 (9.6) | 0.921 |
Microbiology, n(%) | 0.115 | ||
P. aeruginosa | 13 (8.3) | 18 (11.5) | |
H. influenzae | 0 (0) | 1 (0.6) | |
NTM or TB | 11 (7.1) | 3 (1.9) | |
Aspergillus | 6 (3.8) | 4 (2.6) | |
Others | 126 (80.8) | 130 (83.3) | |
Etiology, n (%) | 0.891 | ||
Post pulmonary tuberculosis | 31 (19.9) | 29 (18.6) | |
Post other infective | 43 (27.5) | 36 (23.1) | |
COPD | 23 (14.7) | 27 (17.3) | |
Connective tissue disease | 2 (1.3) | 3 (1.9) | |
Immunodeficiency | 0 (0) | 1 (0.6) | |
Others | 7 (4.5) | 10 (6.4) | |
Unknown | 50 (32.1) | 50 (32.1) | |
Lung function | |||
FEV1, % predicted | 56 [39, 79] | 69 [45, 89] | 0.071 |
FVC, % predicted | 68 [56, 87] | 80 [64, 91] | 0.046 |
FEV1/FVC ratio | 70 [52, 79] | 72 [57, 81] | 0.35 |
FACED score | 0.131 | ||
Mild (0–2) | 98 (62.8) | 88 (56.4) | |
Moderate (3–4) | 51 (32.7) | 52 (33.3) | |
Severe (5–7) | 7 (4.5) | 16 (10.3) | |
Age years | 0.098 | ||
≥ 70 years | 49 (31.4) | 63 (40.4) | |
< 70 years | 107 (68.6) | 93 (59.6) | |
FEV1% predicted | 0.077 | ||
< 50% | 33 (21.2) | 31 (14.7) | |
≥ 50% | 122 (22.4) | 123 (37.2) | |
Chronic colonization by P. aeruginosa | 13 (8.3) | 18 (11.5) | 0.344 |
mMRC dyspnoea score | 0.515 | ||
Score I-II | 136 (87.2) | 132 (84.6) | |
Score III-IV | 20 (12.8) | 24 (15.4) | |
Lobes affected | 0.21 | ||
1-2lobes | 74 (47.4) | 63 (40.4) | |
> 2 lobes | 82 (52.6) | 93 (59.6) | |
Exacerbations in the last year | 0.566 | ||
0–2 | 124 (79.5) | 128 (82.1) | |
≥ 3 | 32 (20.5) | 28 (17.9) | |
Treatment | 0.486 | ||
ICS + LABA | 7 (4.5) | 6 (3.8) | |
LABA + LAMA | 2 (1.3) | 0 (0) | |
Long-term (> 2 wk) macrolides | 0 (0) | 0 (0) | |