The role of colchicine in the management of COVID-19: a Meta-analysis

BMC Pulmonary Medicine

Table 2 Meta-analysis for the efficacy of colchicine on mortality in patients with COVID-19

Study	Type of study	Relative Risk	95% CI	P-value
Deftereos et al. 2020	RCT	0.23	0.03–2.14	0.163144
Tardif et al. 2021	RCT	0.56	0.19–1.67	0.081
Lopes et al. 2021	RCT	0.47	0.04–5.45	0.555346
RECOVERY Collaborative Group 2021	RCT	1.01	0.93–1.10	0.77
Sandhu et al. 2020	NRCT	0.21	0.09–0.51	0.00032
Mareev et al. 2021	NRCT	0.48	0.04–5.67	0.57753
Brunetti et al. 2020	Cohort	0.21	0.06–0.71	0.012
Scarsi et al. 2020	Cohort	0.151	0.062–0.368	< 0.0001
Fixed Effect Model		0.911	0.827–1.005	---
Random Effect Model		0.35	0.15–0.79	---

95% CI 95% confidence interval, RCT Randomized controlled clinical trial, NRCT Nonrandomized controlled clinical trial.

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