Fractional exhaled nitric oxide in idiopathic pulmonary arterial hypertension and mixed connective tissue disease complicating pulmonary hypertension

Table 2 Relationship between FeNO levels and clinical parameters in patients with IPAH.

Factors	IPAH: all (54)		IPAH: mild (26)		IPAH: severe (25)
	R	P	R	P	R	P
PFT
FVC, L	-0.101	0.469	-0.235	0.248	-0.122	0.560
FEV1, L	-0.141	0.309	-0.219	0.282	-0.169	0.419
FEV1/FVC	-0.319	0.019	-0.257	0.206	-0.485	0.014
MEF50%	-0.206	0.136	-0.062	0.763	-0.459	0.021
MEF25%	-0.191	0.167	-0.002	0.991	-0.410	0.042
MMEF75/25%	-0.172	0.214	-0.074	0.721	-0.408	0.043
IOS
R5, cmH2O/(L/s)	-0.009	0.950	-0.092	0.663	0.012	0.956
R5%	-0.077	0.583	-0.142	0.497	0.080	0.705
R20, cmH2O/(L/s)	-0.117	0.403	-0.149	0.479	-0.163	0.436
R20%	-0.217	0.119	-0.205	0.325	-0.248	0.232
CPET
restHR	0.136	0.345	0.020	0.924	0.071	0.742
restO2/HR	0.043	0.768	0.266	0.768	-0.065	0.764
restRER	0.073	0.616	-0.026	0.900	0.032	0.881
warmHR	-0.098	0.497	-0.250	0.219	0.026	0.906
warmO2/HR	0.091	0.531	0.317	0.114	-0.089	0.679
warmRER	0.242	0.090	0.287	0.156	0.279	0.188
ATHR	-0.135	0.349	-0.420	0.033	-0.070	0.746
ATO2/HR	0.232	0.105	0.386	0.052	-0.050	0.817
ATRER	0.098	0.499	0.042	0.840	0.397	0.055
PeakHR	-0.150	0.298	-0.266	0.189	-0.332	0.113
PeakO2/HR	0.269	0.059	0.451	0.021	-0.065	0.765
PeakRER	-0.051	0.725	-0.114	0.581	-0.160	0.454
PeakPETO2, mmHg	-0.392	0.005	-0.295	0.144	-0.468	0.024
PeakPETCO2, mmHg	0.293	0.039	0.245	0.586	0.270	0.202

Correlation coefficients were expressed as Spearman correlation coefficients. CPET=cardiopulmonary exercise test; O2/HR= oxygen consumption divided by peak heart rate; HR=Heart rate; RER=Respiratory exchange ratio; PETO2=End-tidal partial pressure for oxygen; PETCO2=end-tidal partial pressure for carbon dioxide. See Table 1 legend for expansion of abbreviations.

ISSN: 1471-2466