Fig. 3

Comparison of changes in outcomes from baseline to each time point between the three treatment groups in the ITT (left panel) and the PP population (right panel). Group 1, medical treatment (MT); Group 2, medical treatment combined with endurance training (MT + ET); Group 3, medical treatment combined with resistance training (MT + RT). Δ: value changes between the baseline and different time points of follow-up. T3, at the end of programs; T6 and T12, at 6 and 12-month follow-up. * Different from the MT group: P < 0.05. ^aDifference between the exercise training groups: P < 0.05. #, the change in value exceeded the minimum clinically important difference (MCID) for the outcome