Table 1 PaO2/FiO2, the indicators of the inflammatory response and oxidative stress in groups (mean ± SD, n = 8)
From: Penehyclidine hydrochloride alleviates lung ischemia-reperfusion injury by inhibiting pyroptosis
T0PaO2/FiO2(mmHg) | T2PaO2/FiO2(mmHg) | W/D | MPO(pg/ml) | IL-1β(ng/l) | IL-18(pg/ml) | MDA(mmol/l) | SOD(pg/ml) | |
|---|---|---|---|---|---|---|---|---|
Sham | 435 ± 26.9∇# | 428 ± 22.41# | 4.1 ± 0.3# | 27.50 ± 6.10# | 22.50 ± 5.55# | 64.22 ± 13.18# | 3.42 ± 0.46# | 46.28 ± 4.94# |
Control | 433 ± 32.35∆* | 302 ± 30.49* | 6.4 ± 0.5* | 49.48 ± 4.95* | 43.79 ± 7.51* | 137.84 ± 21.78* | 7.73 ± 1.23* | 26.90 ± 8.57* |
PHC | 436 ± 31.5∆∇* | 343 ± 32.83*# | 5.2 ± 0.4*# | 38.55 ± 3.95*# | 28.78 ± 3.80*# | 85.34 ± 12.03*# | 5.22 ± 1.09*# | 36.54 ± 3.30*# |