Table 2 Association of HFNC use in the matched cohort with primary and secondary outcomes

Primary outcome

 28-day all-cause mortality^a

0.53 (0.41–0.69)

 < 0.001

0.53 (0.41–0.69)

 < 0.001

Secondary outcomes

 ICU mortality^b

0.52 (0.38–0.71)

 < 0.001

0.58 (0.41–0.82)

0.002

 In-hospital mortality^b

0.51 (0.38–0.68)

 < 0.001

0.54 (0.39–0.74)

 < 0.001

 Length of ICU stay^c

3.28 (2.61–4.02)

 < 0.001

̸

̸

 Length of hospital stay^c

4.55 (3.32–5.80)

 < 0.001

̸

̸