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Table 4 Cmax and AUC0-24h of indacaterol after once-daily inhalation on Days 1 and 14

From: Cardiac safety of indacaterol in healthy subjects: a randomized, multidose, placebo- and positive-controlled, parallel-group thorough QT study

 

Dose (μg)

Cmax (pg/mL)

AUC0-24h (pg·h/mL)

  

mean ± SD

mean ± SD

Day 1

150

252.9 ± 120.84

1202.0 ± 553.93

 

300

537.2 ± 224.23

2639.4 ± 862.08

 

600

1043.8 ± 285.47

5279.1 ± 1155.28

Day 14

150

438.6 ± 196.38

3881.7 ± 1545.39

 

300

858.6 ± 264.16

8137.0 ± 2388.41

 

600

1656.7 ± 540.76

15084.6 ± 3428.15