Dose (μg) | Cmax (pg/mL) | AUC0-24h (pg·h/mL) | |
---|---|---|---|
mean ± SD | mean ± SD | ||
Day 1 | 150 | 252.9 ± 120.84 | 1202.0 ± 553.93 |
300 | 537.2 ± 224.23 | 2639.4 ± 862.08 | |
600 | 1043.8 ± 285.47 | 5279.1 ± 1155.28 | |
Day 14 | 150 | 438.6 ± 196.38 | 3881.7 ± 1545.39 |
300 | 858.6 ± 264.16 | 8137.0 ± 2388.41 | |
600 | 1656.7 ± 540.76 | 15084.6 ± 3428.15 |