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Table 3 Validity, reliability, and pre-test probability of TBNA outcome for diagnosing mediastinal and hilar adenopathies.

From: Validity and reliability of transbronchial needle aspiration for diagnosing mediastinal adenopathies

Pathology Patients Se Sp PPV NPV*** Accuracy
Non-small cell lung carcinoma* 280 68.3% 100% 100% 9.5% 69.3%
Small cell lung carcinoma** 74 93.2% 100% 100% 16.7% 93.2%
Extrapulmonary carcinoma* 44 69.8% 100% 100% 7.1% 70.5%
Sarcoidosis* 57 63.6% 100% 100% 9.1% 64.9%
Tuberculosis* 19 72.2% 100% 100% 16.7% 73.7%
Lymphoma 15 35.7% 100% 100% 10.0% 40.0%
Anthracotic and reactive 91 52.7% - 100% - 52.7%
Total 580 68.0% 100% 100% 10.0% 68.8%
  1. Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value.
  2. * p of sensitivity and accuracy < 0.05 compared with the lymphoma group.
  3. ** p of sensitivity and accuracy < 0.001 compared with all other pathologies.
  4. *** No statistically significant differences between the various pathologies.