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Table 3 Validity, reliability, and pre-test probability of TBNA outcome for diagnosing mediastinal and hilar adenopathies.

From: Validity and reliability of transbronchial needle aspiration for diagnosing mediastinal adenopathies

Pathology

Patients

Se

Sp

PPV

NPV***

Accuracy

Non-small cell lung carcinoma*

280

68.3%

100%

100%

9.5%

69.3%

Small cell lung carcinoma**

74

93.2%

100%

100%

16.7%

93.2%

Extrapulmonary carcinoma*

44

69.8%

100%

100%

7.1%

70.5%

Sarcoidosis*

57

63.6%

100%

100%

9.1%

64.9%

Tuberculosis*

19

72.2%

100%

100%

16.7%

73.7%

Lymphoma

15

35.7%

100%

100%

10.0%

40.0%

Anthracotic and reactive

91

52.7%

-

100%

-

52.7%

Total

580

68.0%

100%

100%

10.0%

68.8%

  1. Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value.
  2. * p of sensitivity and accuracy < 0.05 compared with the lymphoma group.
  3. ** p of sensitivity and accuracy < 0.001 compared with all other pathologies.
  4. *** No statistically significant differences between the various pathologies.