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  1. Content type: Research article

    Malignant endobronchial mass (MEM) has poor prognosis, cryotherapy is reportedly to diagnose MEM, however, the therapeutic role of cryotherapy impacts on survival has not be well addressed.

    Authors: Fu-Tsai Chung, Chun-Liang Chou, Yu-Lun Lo, Chih-Hsi Kuo, Tsai-Yu Wang, Chun-Hwa Wang, Hung-Yu Huang, Horng-Chyuan Lin, Chih-Hao Chang, Chung-Shu Lee, Hao-Cheng Chen and Shu-Min Lin

    Citation: BMC Pulmonary Medicine 2019 19:101

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  2. Content type: Case report

    Pleural involvement by non-tuberculous mycobacteria (NTM) in patients without distinct pulmonary disease is extremely rare. Vertebral osteomyelitis (VO) with or without pulmonary disease is also a rare clinica...

    Authors: Naoki Kadota, Tsutomu Shinohara, Hiroyuki Hino, Yuichiro Goda, Yoshiro Murase, Satoshi Mitarai and Fumitaka Ogushi

    Citation: BMC Pulmonary Medicine 2019 19:100

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  3. Content type: Study protocol

    Asthma is now widely recognised to be a heterogeneous disease. The last two decades have seen the identification of a number of biological targets and development of various novel therapies. Despite this, asth...

    Authors: Adnan Azim, Heena Mistry, Anna Freeman, Clair Barber, Colin Newell, Kerry Gove, Yvette Thirlwall, Matt Harvey, Kimberley Bentley, Deborah Knight, Karen Long, Frances Mitchell, Yueqing Cheng, Judit Varkonyi-Sepp, Wolfgang Grabau, Paddy Dennison…

    Citation: BMC Pulmonary Medicine 2019 19:99

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  4. Content type: Research article

    Lobectomy is the standard treatment for patients with stage I non-small cell lung cancer (NSCLC). Recent studies have shown promising results of stereotactic body radiation therapy (SBRT) in these patients. We...

    Authors: Qingren Lin, Xiaojiang Sun, Ning Zhou, Zhun Wang, Yaping Xu and Yuezhen Wang

    Citation: BMC Pulmonary Medicine 2019 19:98

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  5. Content type: Research article

    Omega-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and derivatives, play a key role in the resolution of inflammation. Higher intake has been lin...

    Authors: Chantal M. Lemoine S, Emily P. Brigham, Han Woo, Corrine K. Hanson, Meredith C. McCormack, Abigail Koch, Nirupama Putcha and Nadia N. Hansel

    Citation: BMC Pulmonary Medicine 2019 19:97

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  6. Content type: Correction

    In the original article [1], the authors reference their intention to use the ‘Morisky Medication Adherence Scale’.

    Authors: Beatrice Huang, Rachel Willard-Grace, Denise De Vore, Jessica Wolf, Chris Chirinos, Stephanie Tsao, Danielle Hessler, George Su and David H. Thom

    Citation: BMC Pulmonary Medicine 2019 19:96

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    The original article was published in BMC Pulmonary Medicine 2017 17:90

  7. Content type: Research article

    Breathlessness is the prominent symptom of chronic obstructive pulmonary disease (COPD). Despite optimal therapeutic management including pharmacological and non-pharmacological interventions, many COPD patien...

    Authors: H. Carette, M. Zysman, C. Morelot-Panzini, J. Perrin, E. Gomez, A. Guillaumot, P. R. Burgel, G. Deslee, P. Surpas, O. Le Rouzic, T. Perez, A. Chaouat, N. Roche and F. Chabot

    Citation: BMC Pulmonary Medicine 2019 19:95

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  8. Content type: Research article

    Physical activity is an important part of life, and hence exercise-induced bronchoconstriction (EIB) can reduce the quality of life. A standardized test is needed to diagnose EIB. The American Thoracic Society...

    Authors: Melanie Dreßler, Theresa Friedrich, Natali Lasowski, Eva Herrmann, Stefan Zielen and Johannes Schulze

    Citation: BMC Pulmonary Medicine 2019 19:94

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  9. Content type: Research article

    Sepsis biomarkers have limited specificity and sensitivity. Few studies have investigated microRNA (miRNA) biomarkers for sepsis secondary to pneumonia. This study aims to investigate the diagnostic and progno...

    Authors: Wenping Zhang, Jianchao Jia, Zi Liu, Dan Si, Lijun Ma and Guojun Zhang

    Citation: BMC Pulmonary Medicine 2019 19:93

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  11. Content type: Research article

    The management and control of pulmonary bacteriologically confirmed (PBC) tuberculosis (TB) also known as infectious TB is important not only to monitor for resistance but also to check for severity, treatment...

    Authors: Nicholas Sebuliba Kirirabwa, Derrick Kimuli, Carol Nanziri, Denis Sama, Syrus Ntudhu, Daniel Ayen Okello, Raymond Byaruhanga, Deus Lukoye and Samuel Kasozi

    Citation: BMC Pulmonary Medicine 2019 19:91

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  12. Content type: Research article

    Few studies have examined the relationships between sputum inflammatory markers and subsequent annual decline in forced expiratory volume in 1 s (dFEV1). This study investigated whether indices of airway inflamma...

    Authors: Natalia Kononova, Liv Ingunn Bjoner Sikkeland, Faiza Mahmood, Maria Vistnes, Johny Kongerud, Gunnar Einvik and Vidar Søyseth

    Citation: BMC Pulmonary Medicine 2019 19:90

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  14. Content type: Research article

    Inhaled anticholinergics, recommended as first-line maintenance treatment for patients with moderate-to-severe chronic obstructive pulmonary disease (COPD), has been demonstrated to be associated with an incre...

    Authors: Wei Yuan, Shan Nie, Haoyan Wang, Qiufen Xu and Nan Jia

    Citation: BMC Pulmonary Medicine 2019 19:88

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  15. Content type: Research article

    Social determinants may influence the incidence and control of tuberculosis (TB). The aim of this study was to evaluate the correlation between social determinants and pulmonary TB (PTB) incidence and treatmen...

    Authors: Alessandra Isabel Zille, Guilherme Loureiro Werneck, Ronir Raggio Luiz and Marcus Barreto Conde

    Citation: BMC Pulmonary Medicine 2019 19:87

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  16. Content type: Correction

    Following publication of the original article [1], the authors flagged an error in Table 2; specifically, within the row beginning ‘Aldrich et al. 2013’ on page 11 of the article PDF.

    Authors: Flynn Slattery, Kylie Johnston, Catherine Paquet, Hunter Bennett and Alan Crockett

    Citation: BMC Pulmonary Medicine 2019 19:86

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    The original article was published in BMC Pulmonary Medicine 2018 18:149

  17. Content type: Research article

    Pulmonary rehabilitation improves exercise capacity and reduces risk of future exacerbation in COPD when performed after an exacerbation. There have been no previous studies of post-exacerbation rehabilitation...

    Authors: James D. Chalmers, Megan L. Crichton, Gill Brady, Simon Finch, Mike Lonergan and Thomas C. Fardon

    Citation: BMC Pulmonary Medicine 2019 19:85

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  18. Content type: Research article

    Gastroesophageal reflux disease (GORD) is highly prevalent in idiopathic pulmonary fibrosis (IPF) and may play a role in its pathogenesis. Recent IPF treatment guidelines suggest that all patients with IPF be ...

    Authors: Helen E. Jo, Tamera J. Corte, Ian Glaspole, Christopher Grainge, Peter M. A. Hopkins, Yuben Moodley, Paul N. Reynolds, Sally Chapman, E. Haydn Walters, Christopher Zappala, Heather Allan, Gregory J. Keir, Wendy A. Cooper, Annabelle M. Mahar, Samantha Ellis, Sacha Macansh…

    Citation: BMC Pulmonary Medicine 2019 19:84

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  19. Content type: Case report

    Rosai-Dorfman disease (RDD) is a rare histiocytosis which involves principally lymph nodes. Thyroid involvement in RDD is a very rare situation, and lung involvement is even rarer.

    Authors: Pietro Gianella, Nicolas Dulguerov, Grégoire Arnoux, Marc Pusztaszeri and Jörg D. Seebach

    Citation: BMC Pulmonary Medicine 2019 19:83

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  20. Content type: Research article

    There is a paucity of data on long term clinical effects of high frequency chest wall oscillation (HFCWO) in the Bronchiectasis population. Other therapies such as nebulized mucolytics and long term antibiotic...

    Authors: Jordan Powner, Andrew Nesmith, Denay P. Kirkpatrick, Jessica K. Nichols, Brent Bermingham and George M. Solomon

    Citation: BMC Pulmonary Medicine 2019 19:82

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  21. Content type: Research article

    In many clinical disorders, there is a relationship between the ratio of the diameter of the main pulmonary artery (mPA) to that of the aorta (Ao) on chest computed tomography (CT). The aim of this study was t...

    Authors: Ji Soo Choi, Sang Hoon Lee, Ah. Young Leem, Joo Han Song, Kyung Soo Chung, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Joon Chang and Song Yee Kim

    Citation: BMC Pulmonary Medicine 2019 19:81

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  22. Content type: Case report

    Systemic artery to pulmonary artery fistulas (SA-PAFs), are extremely rare in people without congenital heart disease. In this group of patients pulmonary arterial hypertension was reported in the single case....

    Authors: Wojciech Jacheć, Andrzej Tomasik, Marcin Kurzyna, Radosław Pietura, Adam Torbicki, Jan Głowacki, Ewa Nowalany-Kozielska and Celina Wojciechowska

    Citation: BMC Pulmonary Medicine 2019 19:80

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  23. Content type: Research article

    In 2017, Australia experienced its highest levels of influenza virus activity since the 2009 pandemic. This allowed detailed comparison of the characteristics of patients with community and hospital-acquired i...

    Authors: Nikita Parkash, Wendy Beckingham, Patiyan Andersson, Paul Kelly, Sanjaya Senanayake and Nicholas Coatsworth

    Citation: BMC Pulmonary Medicine 2019 19:79

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  24. Content type: Research article

    Current clinical practice guidelines for idiopathic pulmonary fibrosis (IPF) conditionally recommend use of pirfenidone and nintedanib. However, an optimal treatment sequence has not been established, and the ...

    Authors: Satoshi Ikeda, Akimasa Sekine, Tomohisa Baba, Takuma Katano, Erina Tabata, Ryota Shintani, Shinko Sadoyama, Hideaki Yamakawa, Tsuneyuki Oda, Ryo Okuda, Hideya Kitamura, Tae Iwasawa, Tamiko Takemura and Takashi Ogura

    Citation: BMC Pulmonary Medicine 2019 19:78

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  25. Content type: Research article

    Preventative medication reduces hospitalisations in people with cystic fibrosis (PWCF) but adherence is poor. We assessed the feasibility of a randomised controlled trial of a complex intervention, which combi...

    Authors: Daniel Hind, Sarah J. Drabble, Madelynne A. Arden, Laura Mandefield, Simon Waterhouse, Chin Maguire, Hannah Cantrill, Louisa Robinson, Daniel Beever, Alexander J. Scott, Sam Keating, Marlene Hutchings, Judy Bradley, Julia Nightingale, Mark I. Allenby, Jane Dewar…

    Citation: BMC Pulmonary Medicine 2019 19:77

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  26. Content type: Case report

    CFTR modulator therapy with ivacaftor is a treatment option for Cystic Fibrosis (CF) patients with at least one copy of a R117H-7T mutation in the CFTR gene. Desirable effects of this therapy are improvement o...

    Authors: Matthias Welsner, Svenja Straßburg, Christian Taube and Sivagurunathan Sutharsan

    Citation: BMC Pulmonary Medicine 2019 19:76

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  27. Content type: Study protocol

    Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease, with a median survival of 2–3 years and variable natural history, characterized by gradual and progressive deterioration. Acute exacerbation of idio...

    Authors: Jean-Marc Naccache, Melissa Montil, Jacques Cadranel, Marine Cachanado, Vincent Cottin, Bruno Crestani, Dominique Valeyre, Benoit Wallaert, Tabassome Simon and Hilario Nunes

    Citation: BMC Pulmonary Medicine 2019 19:75

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  29. Content type: Research article

    The presence of emphysema on computed tomography (CT) is associated with an increased frequency of lung cancer, but the postoperative outcomes of patients with pulmonary emphysema are not well known. The objec...

    Authors: Seijiro Sato, Masaya Nakamura, Yuki Shimizu, Tatsuya Goto, Terumoto Koike, Hiroyuki Ishikawa and Masanori Tsuchida

    Citation: BMC Pulmonary Medicine 2019 19:73

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  30. Content type: Research article

    Acute exacerbation of interstitial lung disease (AE-ILD) is the most serious complication in lung cancer patients with pre-existing ILD receiving chemotherapy. The role of vascular endothelial growth factor (V...

    Authors: Shohei Hamada, Hidenori Ichiyasu, Tokunori Ikeda, Megumi Inaba, Kosuke Kashiwabara, Tomoki Sadamatsu, Nahoko Sato, Kimitaka Akaike, Hiroko Okabayashi, Koichi Saruwatari, Yusuke Tomita, Sho Saeki, Naomi Hirata, Takeshi Yoshinaga and Kazuhiko Fujii

    Citation: BMC Pulmonary Medicine 2019 19:72

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  31. Content type: Research article

    Differentiating bacterial from viral pneumonia is important for guiding targeted management and judicious use of antibiotics. We assessed if clinical characteristics and blood inflammatory biomarkers could be ...

    Authors: Mejbah U. Bhuiyan, Christopher C. Blyth, Rachel West, Jurissa Lang, Tasmina Rahman, Caitlyn Granland, Camilla de Gier, Meredith L. Borland, Ruth B. Thornton, Lea-Ann S. Kirkham, Andrew Martin, Peter C. Richmond, David W. Smith, Adam Jaffe and Thomas L. Snelling

    Citation: BMC Pulmonary Medicine 2019 19:71

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  32. Content type: Research article

    Defective phagocytosis in alveolar macrophages is associated with chronic obstructive pulmonary disease (COPD). Transient receptor potential cation channel subfamily V member 2 (TRPV2), a type of nonselective ...

    Authors: Hiroaki Masubuchi, Manabu Ueno, Toshitaka Maeno, Koichi Yamaguchi, Kenichiro Hara, Hiroaki Sunaga, Hiroki Matsui, Masahiro Nagasawa, Itaru Kojima, Yuko Iwata, Shigeo Wakabayashi and Masahiko Kurabayashi

    Citation: BMC Pulmonary Medicine 2019 19:70

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  33. Content type: Correction

    Following publication of the original

    Authors: Sukyeon Kim, Beomsu Shin, Hyun Lee, Jick Hwan Ha, Kyungjong Lee, Sang-Won Um, Hojoong Kim and Byeong-Ho Jeong

    Citation: BMC Pulmonary Medicine 2019 19:69

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    The original article was published in BMC Pulmonary Medicine 2019 19:14

  34. Content type: Research article

    Risk of exacerbations in chronic obstructive pulmonary disease (COPD) associated with biomass smoke has not been well addressed, although biomass smoke is similar in composition to tobacco smoke.

    Authors: Jaeyoung Cho, Chang-Hoon Lee, Seung-sik Hwang, Ki Uk Kim, Sang Haak Lee, Hye Yun Park, Seoung Ju Park, Kyung Hoon Min, Yeon-Mok Oh, Kwang Ha Yoo and Ki-Suck Jung

    Citation: BMC Pulmonary Medicine 2019 19:68

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  35. Content type: Research article

    Pulmonary Hypertension Association UK (PHA-UK) is the only charity in the UK especially for people affected by pulmonary hypertension (PH). To better understand the impact of PH on patients and carers beyond c...

    Authors: Iain Armstrong, Catherine Billings, David G. Kiely, Janelle Yorke, Carl Harries, Shaun Clayton and Wendy Gin-Sing

    Citation: BMC Pulmonary Medicine 2019 19:67

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  37. Content type: Case report

    Fibrosing interstitial lung disease is the poor prognostic non-infectious lung disease by unknown etiology. Here, we present one case developing interstitial pneumonia with fibrosis after treatment of pneumocy...

    Authors: Tetsuya Suzuki, Yukiko Shimoda, Katsuji Teruya, Hiroyuki Gatanaga, Yoshimi Kikuchi, Shinichi Oka and Koji Watanabe

    Citation: BMC Pulmonary Medicine 2019 19:65

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  38. Content type: Study protocol

    Asthma is a syndrome composed of heterogeneous disease entities. Although it is agreed that proper asthma endo-typing and appropriate type-specific interventions are crucial in the management of asthma, little...

    Authors: Dong In Suh, Dae Jin Song, Hey-Sung Baek, Meeyong Shin, Young Yoo, Ji-Won Kwon, Gwang Cheon Jang, Hyeon-Jong Yang, Eun Lee, Hwan Soo Kim, Ju-Hee Seo, Sung-Il Woo, Hyung Young Kim, Youn Ho Shin, Ju Suk Lee, Jisun Yoon…

    Citation: BMC Pulmonary Medicine 2019 19:64

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  39. Content type: Research article

    Frailty is a state of increased vulnerability that has a significant risk of unfavorable outcomes such as increased dependency and/or death, but little is known about frailty in people with chronic obstructive...

    Authors: Despo Ierodiakonou, Maria Kampouraki, Ioannis Poulonirakis, Polyvios Papadokostakis, Eleftheria Lintovoi, Dimitris Karanassos, Kyriakos Maltezis, Maria Chorti, Evangelos Petrovitsos, Sofia Dimopoulou, Sam Hamind, Ioannis Gialamas, Polyxeni Athanasiou, Vasiliki Bempi, Irene Lambraki and Ioanna Tsiligianni

    Citation: BMC Pulmonary Medicine 2019 19:63

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  40. Content type: Research article

    Relationships between low forced vital capacity (FVC), and morbidity have previously been studied but there are no data available for the Caribbean population. This study assessed the association of low FVC wi...

    Authors: Sateesh Sakhamuri, Fallon Lutchmansingh, Donald Simeon, Liane Conyette, Peter Burney and Terence Seemungal

    Citation: BMC Pulmonary Medicine 2019 19:62

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  41. Content type: Case report

    Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of phospholipoproteinaceous material in the alveoli. The presentation is nonspecific but typically includes dyspnea; th...

    Authors: Dacia S. K. Boyce, John W. Lee, Phalgoon Shah, Judy H. Freeman, Matthew C. Aboudara and David C. Hostler

    Citation: BMC Pulmonary Medicine 2019 19:61

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  42. Content type: Research article

    Cambodia, a lower middle-income country of about 16 million individuals in southeast Asia, endures a high burden of both tuberculosis and other lower respiratory infections. Differentiating tuberculosis from o...

    Authors: Engi F. Attia, Yaty Pho, Somary Nhem, Chandara Sok, Borady By, Dariven Phann, Huy Nob, Sovanndeth Thann, Sinath Yin, Rachael Noce, Chamrouensann Kim, Joanne Letchford, Thomas Fassier, Sarin Chan and T. Eoin West

    Citation: BMC Pulmonary Medicine 2019 19:60

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  43. Content type: Study protocol

    Lung cancer is the leading cause of cancer-related death due in large part to our inability to diagnose it at an early and potentially curable stage. Screening for lung cancer via low dose computed tomographic...

    Authors: Ehab Billatos, Fenghai Duan, Elizabeth Moses, Helga Marques, Irene Mahon, Lindsey Dymond, Charles Apgar, Denise Aberle, George Washko and Avrum Spira

    Citation: BMC Pulmonary Medicine 2019 19:59

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  44. Content type: Research article

    Airflow obstruction is a hallmark of chronic obstructive pulmonary disease (COPD), and is defined as either the ratio between forced expiratory volume in one second and forced vital capacity (FEV1/FVC) < 70% or <...

    Authors: Diana A. van der Plaat, Judith M. Vonk, Lies Lahousse, Kim de Jong, Alen Faiz, Ivana Nedeljkovic, Najaf Amin, Cleo C. van Diemen, Guy G. Brusselle, Yohan Bossé, Corry-Anke Brandsma, Ke Hao, Peter D. Paré, Cornelia M. van Duijn, Dirkje S. Postma and H. Marike Boezen

    Citation: BMC Pulmonary Medicine 2019 19:58

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  45. Content type: Study protocol

    Exercise training is an important component of pulmonary rehabilitation (PR) programmes in chronic obstructive pulmonary disease (COPD), but the great majority of COPD patients who would benefit from PR never ...

    Authors: Anja Frei, Thomas Radtke, Kaba Dalla Lana, Julia Braun, Ramona M. Müller and Milo A. Puhan

    Citation: BMC Pulmonary Medicine 2019 19:57

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  46. Content type: Research article

    Pneumothorax (PTX) is one of the most common complications of transbronchial biopsy (TBB). Previous research suggests that upper pulmonary lobe TBB may be associated with increased risk of PTX development. The...

    Authors: Vladimir Herout, Michaela Heroutova, Zdenek Merta, Ivan Cundrle Jr and Kristian Brat

    Citation: BMC Pulmonary Medicine 2019 19:56

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  47. Content type: Research article

    HOTTIP, a long non-coding RNA located in the HOXA cluster, plays a role in the patterning of tissues with mesodermal components, including the lung. Overexpression of HOXA genes, including HOTTIP, has been associ...

    Authors: Alfons Navarro, Jorge Moises, Sandra Santasusagna, Ramon M. Marrades, Nuria Viñolas, Joan J. Castellano, Jordi Canals, Carmen Muñoz, José Ramírez, Laureano Molins and Mariano Monzo

    Citation: BMC Pulmonary Medicine 2019 19:55

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  48. Content type: Research article

    The increasing prevalence and recognition of bronchiectasis in clinical practice necessitates a better understanding of the economic disease burden to improve the management and achieve better clinical and eco...

    Authors: Pieter C. Goeminne, Francisco Hernandez, Roland Diel, Anna Filonenko, Rowena Hughes, Fabian Juelich, George M. Solomon, Alex Upton, Kamonthip Wichmann, Weiwei Xu and James D. Chalmers

    Citation: BMC Pulmonary Medicine 2019 19:54

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  49. Content type: Research article

    Studies investigating the role of hyperoxia in critically ill patients have reported conflicting results. We did this analysis to reveal the effect of hyperoxia in the patients admitted to the intensive care u...

    Authors: Yue-Nan Ni, Yan-Mei Wang, Bin-Miao Liang and Zong-An Liang

    Citation: BMC Pulmonary Medicine 2019 19:53

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