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  1. Study protocol

    Effect of counselling during pulmonary rehabilitation on self-determined motivation towards physical activity in people with chronic obstructive pulmonary disease – protocol of a mixed methods study

    Physical activity promotion in people with Chronic Obstructive Pulmonary Disease (COPD) is focus of research and public health. Patient-centred interventions like counselling are promising approaches to help p...

    Anne-Kathrin Rausch-Osthoff, Nicola Greco, Ariane Schwank, Swantje Beyer, David Gisi, Mandy Scheermesser, André Meichtry, Noriane Sievi, Thomas Hess and Markus Wirz

    BMC Pulmonary Medicine 2017 17:115

    Published on: 17 August 2017

  2. Research article

    FEV1 and FVC and systemic inflammation in a spinal cord injury cohort

    Systemic inflammation has been associated with reduced pulmonary function in individuals with and without chronic medical conditions. Individuals with chronic spinal cord injury (SCI) have clinical characteris...

    Jaime E. Hart, Rebekah Goldstein, Palak Walia, Merilee Teylan, Antonio Lazzari, Carlos G. Tun and Eric Garshick

    BMC Pulmonary Medicine 2017 17:113

    Published on: 15 August 2017

  3. Study protocol

    A multi-center randomized, controlled, open-label trial evaluating the effects of eosinophil-guided corticosteroid-sparing therapy in hospitalised patients with COPD exacerbations – The CORTICO steroid reduction in COPD (CORTICO-COP) study protocol

    The most commonly applied treatment for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is a 5-day course of high-dose systemic corticosteroids. However, this treatment has not been shown...

    Pradeesh Sivapalan, Mia Moberg, Josefin Eklöf, Julie Janner, Jørgen Vestbo, Rasmus Rude Laub, Andrea Browatzki, Karin Armbruster, Jon Torgny Wilcke, Niels Seersholm, Ulla Møller Weinreich, Ingrid Louise Titlestad, Helle Frost Andreassen, Charlotte Suppli Ulrik, Uffe Bødtger, Thyge Lynghøj Nielsen…

    BMC Pulmonary Medicine 2017 17:114

    Published on: 15 August 2017

  4. Research article

    Association between Charlson comorbidity index score and outcome in patients with stage IIIB-IV non-small cell lung cancer

    This retrospective study investigated the association between the Charlson comorbidity index (CCI) score and the survival of patients with stage IIIB-IV (advanced, non-resectable) non-small cell lung cancer (N...

    Lei Zhao, Lai-Han Leung, Jing Wang, Huihui Li, Juanjuan Che, Lian Liu, Xiaojun Yao and Bangwei Cao

    BMC Pulmonary Medicine 2017 17:112

    Published on: 15 August 2017

  5. Research article

    Serological and morphological prognostic factors in patients with interstitial pneumonia with autoimmune features

    To identify the prognostic factors for survival in patients with interstitial pneumonia with autoimmune features (IPAF) who meet the serological domain of the IPAF criteria.

    Yuhei Ito, Machiko Arita, Shogo Kumagai, Reoto Takei, Maki Noyama, Fumiaki Tokioka, Keisuke Nishimura, Takashi Koyama, Kenji Notohara and Tadashi Ishida

    BMC Pulmonary Medicine 2017 17:111

    Published on: 14 August 2017

  6. Research article

    Cathepsin-S degraded decorin are elevated in fibrotic lung disorders – development and biological validation of a new serum biomarker

    Decorin is one of the most abundant proteoglycans of the extracellular matrix and is mainly secreted and deposited in the interstitial matrix by fibroblasts where it plays an important role in collagen turnove...

    S.N. Kehlet, C.L. Bager, N. Willumsen, B. Dasgupta, C. Brodmerkel, M. Curran, S. Brix, D.J. Leeming and M. A. Karsdal

    BMC Pulmonary Medicine 2017 17:110

    Published on: 9 August 2017

  7. Research article

    Diagnostic value of medical thoracoscopy in malignant pleural effusion

    Medical thoracoscopy has been shown to be an efficacious procedure in diagnosing unexplained exudative pleural effusions with excellent safety. This study aimed to assess the diagnostic significance of thoraco...

    Yan-Bing Wu, Li-Li Xu, Xiao-Juan Wang, Zhen Wang, Jun Zhang, Zhao-Hui Tong and Huan-Zhong Shi

    BMC Pulmonary Medicine 2017 17:109

    Published on: 4 August 2017

  8. Research article

    Prognostic nomogram for inpatients with asthma exacerbation

    Asthma exacerbation may require a visit to the emergency room as well as hospitalization and can occasionally be fatal. However, there is limited information about the prognostic factors for asthma exacerbatio...

    Wakae Hasegawa, Yasuhiro Yamauchi, Hideo Yasunaga, Hideyuki Takeshima, Yukiyo Sakamoto, Taisuke Jo, Yusuke Sasabuchi, Hiroki Matsui, Kiyohide Fushimi and Takahide Nagase

    BMC Pulmonary Medicine 2017 17:108

    Published on: 4 August 2017

  9. Case report

    Lymphangioleiomyomatosis, multifocal micronodular pneumocyte hyperplasia, and sarcoidosis: more pathological findings in the same chest CT, or a single pathological pathway?

    Autoimmune hepatitis/primary biliary cirrhosis overlap syndrome, lymphangioleiomyomatosis/tuberous sclerosis complex (LAM-TSC), and sarcoidosis are three rare diseases. Here we present, to the best of our know...

    Fabiano Di Marco, Giuseppina Palumbo, Silvia Terraneo, Gianluca Imeri, Elena Lesma, Nicola Sverzellati, Angela Peron, Lorenzo Gualandri, Maria Paola Canevini and Stefano Centanni

    BMC Pulmonary Medicine 2017 17:107

    Published on: 28 July 2017

  10. Research article

    Air pollution exposure is associated with MRSA acquisition in young U.S. children with cystic fibrosis

    The role of air pollution in increasing susceptibility to respiratory tract infections in the cystic fibrosis (CF) population has not been well described. We recently demonstrated that chronic PM2.5 exposure is a...

    Kevin J. Psoter, Anneclaire J. De Roos, Jon Wakefield, Jonathan D. Mayer and Margaret Rosenfeld

    BMC Pulmonary Medicine 2017 17:106

    Published on: 27 July 2017

  11. Research article

    Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation

    Positive-pressure mechanical ventilation is essential in assisting patients with respiratory failure in the intensive care unit and facilitating oxygenation in the operating room. However, it was also recogniz...

    Nan-Chun Wu, Fan-Ting Liao, Hao-min Cheng, Shih-Hsien Sung, Yu-Chun Yang and Jiun-Jr Wang

    BMC Pulmonary Medicine 2017 17:105

    Published on: 26 July 2017

  12. Research article

    Prognosis and longitudinal changes of physical activity in idiopathic pulmonary fibrosis

    Physical activity (PA) is associated with disease severity in idiopathic pulmonary fibrosis (IPF), but longitudinal studies evaluating its prognostic value and changes over time are lacking.

    Thomas Bahmer, Anne-Marie Kirsten, Benjamin Waschki, Klaus F. Rabe, Helgo Magnussen, Detlef Kirsten, Marco Gramm, Simone Hummler, Eva Brunnemer, Michael Kreuter and Henrik Watz

    BMC Pulmonary Medicine 2017 17:104

    Published on: 25 July 2017

  13. Case report

    Successful rescue combination of extracorporeal membrane oxygenation, high-frequency oscillatory ventilation and prone positioning for the management of severe methicillin-resistant Staphylococcus aureus pneumonia complicated by pneumothorax: a case report and literature review

    To describe the experience of combination therapy with extracorporeal membrane oxygenation(ECMO), high-frequency oscillatory ventilation(HFOV) and prone positioning in treating severe respiratory failure cause...

    Hangyong He, Hao Wang, Xuyan Li, Xiao Tang, Rui Wang, Bing Sun and Zhaohui Tong

    BMC Pulmonary Medicine 2017 17:103

    Published on: 20 July 2017

  14. Research article

    Analysis of long term CD4+CD25highCD127- T-reg cells kinetics in peripheral blood of lung transplant recipients

    The role of CD4+CD25highCD127− T-reg cells in solid-organ Transplant (Tx) acceptance has been extensively studied. In previous studies on kidney and liver recipients, peripheral T-reg cell counts were associated ...

    Davide Piloni, Monica Morosini, Sara Magni, Alice Balderacchi, Luigia Scudeller, Emanuela Cova, Tiberio Oggionni, Giulia Stella, Carmine Tinelli, Filippo Antonacci, Andrea Maria D’Armini and Federica Meloni

    BMC Pulmonary Medicine 2017 17:102

    Published on: 18 July 2017

  16. Case report

    Monitoring clinical and microbiological evolution of a cystic fibrosis patient over 26 years: experience of a Brazilian CF Centre

    Burkholderia cepacia complex is a group of opportunistic pathogens in cystic fibrosis (CF) patients believed to be associated with poor prognosis and patient-to-patient transmissibilit...

    Cassiana da Costa Ferreira Leite, Tania Wrobel Folescu, Mônica de Cássia Firmida, Renata Wrobel Folescu Cohen, Robson Souza Leão, Flávia Alvim Dutra de Freitas, Rodolpho Mattos Albano, Claudia Henrique da Costa and Elizabeth Andrade Marques

    BMC Pulmonary Medicine 2017 17:100

    Published on: 14 July 2017

  17. Research article

    Patient preferences for dry powder inhaler attributes in asthma and chronic obstructive pulmonary disease in France: a discrete choice experiment

    Dry powder inhalers (DPIs) are often used in asthma and chronic obstructive pulmonary disease (COPD) therapies. Using the discrete choice experiment (DCE) methodology, this study conducted in France was design...

    Natalia Hawken, Saku Torvinen, Mohamed-Elmoctar Neine, Ikbel Amri, Mondher Toumi, Samuel Aballéa, Adam Plich and Nicolas Roche

    BMC Pulmonary Medicine 2017 17:99

    Published on: 6 July 2017

  19. Research article

    Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia

    Bronchopulmonary dysplasia (BPD) is a strong risk factor for respiratory morbidity in children born preterm. Our aims were to evaluate lung function in adolescents born preterm with and without a history of BP...

    Petra Um-Bergström, Jenny Hallberg, Per Thunqvist, Eva Berggren-Broström, Martin Anderson, Gunilla Adenfelt, Gunnar Lilja, Giovanni Ferrara, C. Magnus Sköld and Erik Melén

    BMC Pulmonary Medicine 2017 17:97

    Published on: 30 June 2017

  20. Research article

    Prevalence and associated risk factors of chronic bronchitis in First Nations people

    Inadequate housing, low family income, household smoking, personal smoking status, and poor schooling are some of the conditions that have been significantly associated with the prevalence and incidence of chr...

    Punam Pahwa, Chandima P. Karunanayake, Donna C. Rennie, Joshua A. Lawson, Vivian R. Ramsden, Kathleen McMullin, P. Jenny Gardipy, Judy MacDonald, Sylvia Abonyi, Jo-Ann Episkenew and James A. Dosman

    BMC Pulmonary Medicine 2017 17:95

    Published on: 29 June 2017

  21. Research article

    Bacteraemia and fungaemia in cystic fibrosis patients with febrile pulmonary exacerbation: a prospective observational study

    Bloodstream pathogens can be identified by multiplex PCR (SeptiFast (SF)) or blood culture (BC); whether these pathogens are present in cystic fibrosis (CF) patients during febrile pulmonary exacerbations (FPE...

    Joerg Grosse-Onnebrink, Florian Stehling, Eva Tschiedel, Margarete Olivier, Uwe Mellies, Rene Schmidt, Jan Buer, Peter-Micheal Rath and Joerg Steinmann

    BMC Pulmonary Medicine 2017 17:96

    Published on: 29 June 2017

  22. Research article

    White matter lesions characterise brain involvement in moderate to severe chronic obstructive pulmonary disease, but cerebral atrophy does not

    Brain pathology is relatively unexplored in chronic obstructive pulmonary disease (COPD). This study is a comprehensive investigation of grey matter (GM) and white matter (WM) changes and how these relate to d...

    Catherine A. Spilling, Paul W. Jones, James W. Dodd and Thomas R. Barrick

    BMC Pulmonary Medicine 2017 17:92

    Published on: 19 June 2017

  25. Case report

    Monitoring the electric activity of the diaphragm during noninvasive positive pressure ventilation: a case report

    In patients with post-extubation respiratory distress, delayed reintubation may worsen clinical outcomes. Objective measures of extubation failure at the bedside are lacking, therefore clinical parameters are ...

    Fabia Diniz-Silva, Anna Miethke-Morais, Adriano M. Alencar, Henrique T. Moriya, Pedro Caruso, Eduardo L. V. Costa and Juliana C. Ferreira

    BMC Pulmonary Medicine 2017 17:91

    Published on: 17 June 2017

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