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BMC Pulmonary Medicine

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  1. Content type: Research article

    NKX2–1, a key molecule in lung development, is highly expressed in non-small cell lung cancer (NSCLC), particularly in lung adenocarcinoma (ADK), where it is a diagnostic marker. Studies of the prognostic role...

    Authors: Jorge Moisés, Alfons Navarro, Sandra Santasusagna, Nuria Viñolas, Laureano Molins, José Ramirez, Jeisson Osorio, Adela Saco, Joan Josep Castellano, Carmen Muñoz, Sara Morales, Mariano Monzó and Ramón María Marrades

    Citation: BMC Pulmonary Medicine 2017 17:197

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  2. Content type: Research article

    Assessment of delays in seeking care and diagnosis of tuberculosis is essential to evaluate effectiveness of tuberculosis control programs, and identify programmatic impediments. Thus, this review of studies a...

    Authors: Fentabil Getnet, Meaza Demissie, Nega Assefa, Bizatu Mengistie and Alemayehu Worku

    Citation: BMC Pulmonary Medicine 2017 17:202

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  3. Content type: Research article

    No drugs have been approved for the treatment of patients with pulmonary hypertension (PH) secondary to idiopathic pulmonary fibrosis (IPF), particularly those with idiopathic honeycomb lung. This study was co...

    Authors: Yosuke Tanaka, Mitsunori Hino and Akihiko Gemma

    Citation: BMC Pulmonary Medicine 2017 17:200

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  4. Content type: Research article

    In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (...

    Authors: Hirofumi Kamata, Takanori Asakura, Shoji Suzuki, Ho Namkoong, Kazuma Yagi, Yohei Funatsu, Satoshi Okamori, Shunsuke Uno, Yoshifumi Uwamino, Hiroshi Fujiwara, Tomoyasu Nishimura, Makoto Ishii, Tomoko Betsuyaku and Naoki Hasegawa

    Citation: BMC Pulmonary Medicine 2017 17:198

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  5. Content type: Research article

    Acute respiratory failure (ARF) is a common and life-threatening medical emergency in patients admitted to the hospital. Currently, there is a lack of large-scale evidence on the use of high-flow nasal cannula...

    Authors: Youfeng Zhu, Haiyan Yin, Rui Zhang and Jianrui Wei

    Citation: BMC Pulmonary Medicine 2017 17:201

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  6. Content type: Case report

    To improve the understanding of acute fibrinous and organizing pneumonia (AFOP), we present one case of AFOP proven by percutaneous lung biopsy along with clinical features, chest imaging and pathology.

    Authors: Shengsong Chen, Hong Zhou, Lingling Yu, Bo Tong, Zuke Xiao and Sisi Fan

    Citation: BMC Pulmonary Medicine 2017 17:203

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  7. Content type: Research article

    Bronchopulmonary dysplasia (BPD) is a neonatal chronic lung disease characterized by impaired pulmonary alveolar development in preterm infants. Until now, little is known about the molecular and cellular basi...

    Authors: Cheng Cai, Jiajun Qiu, Gang Qiu, Yihuan Chen, Zhijun Song, Juan Li and Xiaohui Gong

    Citation: BMC Pulmonary Medicine 2017 17:199

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  8. Content type: Research article

    Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, ho...

    Authors: Hai-Lin Zhang, Min Tan, Ai-Min Qiu, Zhang Tao and Chang-Hui Wang

    Citation: BMC Pulmonary Medicine 2017 17:196

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  9. Content type: Research article

    Previous studies have indicated that chitinase 3-like 1 (CHI3L1) gene rs4950928 polymorphism and acidic mammalian chitinase (AMCase or CHIA) gene rs10494132 polymorphism are associated with the risk of asthma....

    Authors: Yanting Zhu, Xin Yan, Cui Zhai, Lan Yang and Manxiang Li

    Citation: BMC Pulmonary Medicine 2017 17:193

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  10. Content type: Research article

    Excessive daytime sleepiness may be determined by a number of factors including personal characteristics, co-morbidities and socio-economic conditions. In this study we identified factors associated with exces...

    Authors: Ina van der Spuy, Chandima P. Karunanayake, James A. Dosman, Kathleen McMullin, Gaungming Zhao, Sylvia Abonyi, Donna C. Rennie, Joshua Lawson, Shelley Kirychuk, Judith MacDonald, Laurie Jimmy, Niels Koehncke, Vivian R. Ramsden, Mark Fenton, Gregory P. Marchildon, Malcolm King…

    Citation: BMC Pulmonary Medicine 2017 17:192

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  11. Content type: Research article

    Macrophages stand at the forefront of both innate and adapted immunity through their capacities to recognize, engulf, and eliminate foreign particles, and to stimulate adapted immune cells. They are also invol...

    Authors: Jingzhu Lv, Xiaoyan He, Hongtao Wang, Zhaohua Wang, Gabriel T. Kelly, Xiaojing Wang, Yin Chen, Ting Wang and Zhongqing Qian

    Citation: BMC Pulmonary Medicine 2017 17:194

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  12. Content type: Research article

    Recent studies have shown that both adenosine monophosphate activated protein kinase (AMPK) and the mammalian target of rapamycin (mTOR) are energy sensors and are related to autophagy. Our recent reports have...

    Authors: Di Gui, Zhimin Cui, Lin Zhang, Chang Yu, Dan Yao, Min Xu, Mayun Chen, Peiliang Wu, Guoping Li, Liangxing Wang and Xiaoying Huang

    Citation: BMC Pulmonary Medicine 2017 17:191

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  13. Content type: Research article

    It is crucial to develop novel diagnostic approaches for determining if peripheral lung nodules are malignant, as such nodules are frequently detected due to the increased use of chest computed tomography scan...

    Authors: Akifumi Uchida, Takuya Samukawa, Tomohiro Kumamoto, Masahiro Ohshige, Kazuhito Hatanaka, Yoshihiro Nakamura, Keiko Mizuno, Ikkou Higashimoto, Masami Sato and Hiromasa Inoue

    Citation: BMC Pulmonary Medicine 2017 17:195

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  14. Content type: Research article

    Multiple breath washout (MBW) became a valuable research tool assessing ventilation heterogeneity. However, routine clinical application still faces several challenges. Deriving MBW parameters from three techn...

    Authors: Frederik Trinkmann, Johannes Götzmann, Daniel Saur, Michele Schroeter, Katharina Roth, Ksenija Stach, Martin Borggrefe, Joachim Saur, Ibrahim Akin and Julia D. Michels

    Citation: BMC Pulmonary Medicine 2017 17:185

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  15. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide. The study aimed to determine and compare the prevalence of COPD in the general population aged 45-74 years old accor...

    Authors: Edgardo Sobrino, Vilma E. Irazola, Laura Gutierrez, Chung-Shiuan Chen, Fernando Lanas, Matías Calandrelli, Jacqueline Ponzo, Nora Mores, Pamela Serón, Allison Lee, Jiang He and Adolfo L. Rubinstein

    Citation: BMC Pulmonary Medicine 2017 17:187

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  16. Content type: Research article

    Transbronchial biopsy for peripheral pulmonary lesions is generally performed under X-ray fluoroscopy. Virtual bronchoscopic navigation (VBN) is a method in which virtual images of the bronchial route to the l...

    Authors: Fumihiro Asano, Takashi Ishida, Naofumi Shinagawa, Noriaki Sukoh, Masaki Anzai, Kenya Kanazawa, Akifumi Tsuzuku and Satoshi Morita

    Citation: BMC Pulmonary Medicine 2017 17:184

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  17. Content type: Research article

    Systemic morphine has evidence to support its use for reducing breathlessness in patients with severe chronic obstructive pulmonary disease (COPD). The effectiveness of the nebulized route, however, has not ye...

    Authors: Piotr Janowiak, Małgorzata Krajnik, Zygmunt Podolec, Tomasz Bandurski, Iwona Damps-Konstańska, Piotr Sobański, David C. Currow and Ewa Jassem

    Citation: BMC Pulmonary Medicine 2017 17:186

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  18. Content type: Research article

    Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machine...

    Authors: Christopher D. Pascoe, Ma’en Obeidat, Bryna A. Arsenault, Yunlong Nie, Stephanie Warner, Dorota Stefanowicz, Samuel J. Wadsworth, Jeremy A. Hirota, S. Jasemine Yang, Delbert R. Dorscheid, Chris Carlsten, Tillie L. Hackett, Chun Y. Seow and Peter D. Paré

    Citation: BMC Pulmonary Medicine 2017 17:189

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  19. Content type: Research article

    Pulmonary exacerbations (PEx) in school aged children and adults with cystic fibrosis (CF) lead to increased morbidity and lung function decline. However, the effect of exacerbations in young children with CF ...

    Authors: Jordana E. Hoppe, Brandie D. Wagner, Scott D. Sagel, Frank J. Accurso and Edith T. Zemanick

    Citation: BMC Pulmonary Medicine 2017 17:188

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  20. Content type: Research article

    Accumulating evidence suggests that high-density lipoprotein (HDL) cholesterol is associated with pulmonary function and pulmonary disorders. The aim of this study was to evaluate the association between HDL c...

    Authors: Ji Hye Park, Seyeon Mun, Dong Phil Choi, Joo Young Lee and Hyeon Chang Kim

    Citation: BMC Pulmonary Medicine 2017 17:190

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  21. Content type: Research article

    The ability of interleukins (ILs) to differentiate tuberculous pleural effusion from other types of effusion is controversial. The aim of our study was to summarize the evidence for its use of ruling out or in...

    Authors: Ni Zeng, Chun Wan, Jiangyu Qin, Yanqiu Wu, Ting Yang, Yongchun Shen, Fuqiang Wen and Lei Chen

    Citation: BMC Pulmonary Medicine 2017 17:180

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  22. Content type: Research article

    Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a valuable life support in acute respiratory distress syndrome (ARDS) in adult patients. However, the success of VV-ECMO is known to be influenced by...

    Authors: Meng-Yu Wu, Yu-Sheng Chang, Chung-Chi Huang, Tzu-I Wu and Pyng-Jing Lin

    Citation: BMC Pulmonary Medicine 2017 17:181

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  23. Content type: Research article

    Obstructive sleep apnea (OSA) is associated with increased cardiovascular risk. This study aim to assess differences in changes in arterial stiffness of two groups of patients, defined as having daytime sleepi...

    Authors: Maria Alexandra Mineiro, Pedro Marques da Silva, Marta Alves, Ana Luísa Papoila, Maria João Marques Gomes and João Cardoso

    Citation: BMC Pulmonary Medicine 2017 17:182

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  24. Content type: Research article

    Despite the recent increasing worldwide attention towards pulmonary hypertension (PH), its epidemiology remains poorly described in Africa. Accordingly, we performed a systematic review and meta-analysis of PH...

    Authors: Jean Joel Bigna, Jean Jacques Noubiap, Jobert Richie Nansseu and Leopold Ndemnge Aminde

    Citation: BMC Pulmonary Medicine 2017 17:183

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  25. Content type: Research article

    Guidelines recommend timely evaluation of patients with suspected lung cancer. We evaluated the impact of a Rapid Investigation Clinic (RIC) on timeliness of lung cancer diagnosis and treatment between Februar...

    Authors: Nicole Ezer, Asma Navasakulpong, Kevin Schwartzman, Linda Ofiara and Anne V. Gonzalez

    Citation: BMC Pulmonary Medicine 2017 17:178

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