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BMC Pulmonary Medicine


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  1. Content type: Research article

    Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations?

    Authors: Adrian Egli, Jyotshna Mandal, Desiree M. Schumann, Michael Roth, Brad Thomas, D. Lorne Tyrrell, Francesco Blasi, Kostantinos Kostikas, Wim Boersma, Branislava Milenkovic, Alicia Lacoma, Katharina Rentsch, Gernot G. U. Rohde, Renaud Louis, Joachim G. Aerts, Tobias Welte…

    Citation: BMC Pulmonary Medicine 2018 18:51

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  2. Content type: Research article

    Some epidemiological evidence has shown a relation between ambient air pollution and adverse health outcomes. The aim of this study was to investigate the effect of air pollution on mortality from respiratory ...

    Authors: Azizallah Dehghan, Narges Khanjani, Abbas Bahrampour, Gholamreza Goudarzi and Masoud Yunesian

    Citation: BMC Pulmonary Medicine 2018 18:49

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  3. Content type: Case report

    Mortality related to asthma has decreased worldwide since the introduction of inhaled corticosteroid therapy in the past decades. However, there are still some asthma fatalities identified mainly in population...

    Authors: Thais Mauad, Felipe B. P. do Nascimento, Marisa Dolhnikoff, Milena C. M. Picka and Paulo H. N. Saldiva

    Citation: BMC Pulmonary Medicine 2018 18:50

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  4. Content type: Research article

    Allergic asthma is the most prevalent phenotype of severe asthma where treatment with omalizumab (OMB) has been proven to be particularly beneficial. In Poland, OMB therapy is available and reimbursed within a...

    Authors: Karina Jahnz-Różyk, Joanna Lis, Marta Warchoł and Aleksandra Kucharczyk

    Citation: BMC Pulmonary Medicine 2018 18:48

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  5. Content type: Research article

    Club cell protein-16 (CC16) expression has been associated with smoking-related lung function decline. The study hypothesis was that CC16 expression in both serum and bronchial epithelium is associated with lu...

    Authors: David Chi-Leung Lam, Hoi-Hin Kwok, Wai-Cho Yu, Fanny Wai-San Ko, Cheuk-Yin Tam, Arthur Chun-Wing Lau, Daniel Yee-Tak Fong and Mary Sau-Man Ip

    Citation: BMC Pulmonary Medicine 2018 18:47

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  6. Content type: Research article

    Interventional bronchoscopy is considered an effective treatment option for malignant central airway obstruction (MCAO). However, there are few reports of interventional bronchoscopy in patients with MCAOs due...

    Authors: Beomsu Shin, Boksoon Chang, Hojoong Kim and Byeong-Ho Jeong

    Citation: BMC Pulmonary Medicine 2018 18:46

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  7. Content type: Research article

    Interstitial lung disease (ILD) is a prognostic indicator of poor outcome in myositis. Although the pathogenesis of myositis-associated ILD is not well understood, neutrophils are thought to play a pivotal rol...

    Authors: Noriho Sakamoto, Hiroshi Ishimoto, Tomoyuki Kakugawa, Minoru Satoh, Tomoko Hasegawa, Shin Tanaka, Atsuko Hara, Shota Nakashima, Hirokazu Yura, Takuto Miyamura, Hanako Koyama, Towako Morita, Seiko Nakamichi, Yasushi Obase, Yuji Ishimatsu and Hiroshi Mukae

    Citation: BMC Pulmonary Medicine 2018 18:44

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  8. Content type: Research article

    Previous studies have suggested that antibodies against human leukocyte antigen (HLA) are associated with worse outcomes in lung transplantation. However, little is known about the factors associated with outc...

    Authors: Ji Eun Park, Chi Young Kim, Moo Suk Park, Joo Han Song, Young Sam Kim, Jin Gu Lee, Hyo Chae Paik and Song Yee Kim

    Citation: BMC Pulmonary Medicine 2018 18:45

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  9. Content type: Research article

    Bacterial respiratory infections (BRI) are major complications contributing to increased morbidity and mortality after lung transplantation (LT). This study analyzed epidemiology and outcome of 175 consecutive...

    Authors: Sebastien Tanaka, Claire Geneve, Gianpiero Tebano, Nathalie Grall, Pascal Piednoir, Régis Bronchard, Mathieu Godement, Enora Atchade, Pascal Augustin, Herve Mal, Yves Castier, Philippe Montravers and Mathieu Desmard

    Citation: BMC Pulmonary Medicine 2018 18:43

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  10. Content type: Research article

    There is a need for more powerful methods to identify low-effect SNPs that contribute to hereditary COPD pathogenesis. We hypothesized that SNPs contributing to COPD risk through cis-regulatory effects are enrich...

    Authors: Jiyoun Yeo, Diego A. Morales, Tian Chen, Erin L. Crawford, Xiaolu Zhang, Thomas M. Blomquist, Albert M. Levin, Pierre P. Massion, Douglas A. Arenberg, David E. Midthun, Peter J. Mazzone, Steven D. Nathan, Ronald J. Wainz, Patrick Nana-Sinkam, Paige F. S. Willey, Taylor J. Arend…

    Citation: BMC Pulmonary Medicine 2018 18:42

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  11. Content type: Research article

    Aldosterone is a mineralocorticoid hormone critically involved in arterial blood pressure regulation. Although pharmacological aldosterone antagonism reduces mortality and morbidity among patients with severe ...

    Authors: Mario Boehm, Nadine Arnold, Adam Braithwaite, Josephine Pickworth, Changwu Lu, Tatyana Novoyatleva, David G. Kiely, Friedrich Grimminger, Hossein A. Ghofrani, Norbert Weissmann, Werner Seeger, Allan Lawrie, Ralph T. Schermuly and Baktybek Kojonazarov

    Citation: BMC Pulmonary Medicine 2018 18:41

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  12. Content type: Study protocol

    Exercise training is an integral component of evidence-based management programs for many chronic cardiac and respiratory conditions. Despite this, there are limited high-quality studies available on the signi...

    Authors: Norman R. Morris, Menaka Louis, Wendy Strugnell, Julie Harris, Aaron Lin, John Feenstra and Helen Seale

    Citation: BMC Pulmonary Medicine 2018 18:40

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  13. Content type: Case report

    Actinomycosis is a rare bacterial infection caused by Actinomyces. The symptom of actinomycosis is nonspecific and radiological images present as a slow-progressive mass lesion similarly to malignancies. Thus, it...

    Authors: Munemasa Nagao, Akihisa Fukuda, Takeshi Matsumura, Toshiyuki Kimura and Hiroshi Seno

    Citation: BMC Pulmonary Medicine 2018 18:39

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  14. Content type: Research article

    An adequate threshold for the Clinical Chronic Obstructive Pulmonary Disease (COPD) Questionnaire (CCQ) defining more symptomatic COPD patients has not been determined. We aimed to determine the efficacy of th...

    Authors: Yong Suk Jo, Sangshin Park, Deog Kyeom Kim, Chul-Gyu Yoo and Chang-Hoon Lee

    Citation: BMC Pulmonary Medicine 2018 18:38

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  15. Content type: Research article

    The prison situations are notorious for causing interruptions of tuberculosis (TB) treatment and occurrence of unfavorable outcomes. In Ethiopian prisons, though TB treatment programs exist, treatment outcome ...

    Authors: Kelemework Adane, Mark Spigt and Geert-Jan Dinant

    Citation: BMC Pulmonary Medicine 2018 18:37

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  16. Content type: Research article

    Although the impact of therapeutic thoracentesis on lung function and blood gases has been evaluated in several studies, some physiological aspects of pleural fluid withdrawal remain unknown. The aim of the st...

    Authors: Monika Zielinska-Krawczyk, Elzbieta M. Grabczak, Marcin Michnikowski, Krzysztof Zielinski, Piotr Korczynski, Anna Stecka, Tomasz Golczewski and Rafal Krenke

    Citation: BMC Pulmonary Medicine 2018 18:36

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  17. Content type: Research article

    Infection with Burkholderia cepacia complex (Bcc) results in a heterogeneous clinical course ranging from asymptomatic colonization of the airways to fulminant respiratory failure in patients with cystic fibrosis...

    Authors: Bryan A. Garcia, Jacque L. Carden, Dana L. Goodwin, Tim A. Smith, Amit Gaggar, Kevin Leon, Veena B. Antony, Steven M. Rowe and George M. Solomon

    Citation: BMC Pulmonary Medicine 2018 18:35

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  18. Content type: Research article

    Thus far, no algorithms have been developed to automatically extract patients who meet Asthma Predictive Index (API) criteria from the Electronic health records (EHR) yet. Our objective is to develop and valid...

    Authors: Harsheen Kaur, Sunghwan Sohn, Chung-Il Wi, Euijung Ryu, Miguel A. Park, Kay Bachman, Hirohito Kita, Ivana Croghan, Jose A. Castro-Rodriguez, Gretchen A. Voge, Hongfang Liu and Young J. Juhn

    Citation: BMC Pulmonary Medicine 2018 18:34

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  19. Content type: Research article

    Questionnaires can be used to assess perceived indoor air quality and symptoms in schools. Questionnaires for primary school aged children have traditionally been parent-administered, but self-administered que...

    Authors: Jussi Lampi, Sari Ung-Lanki, Päivi Santalahti and Juha Pekkanen

    Citation: BMC Pulmonary Medicine 2018 18:32

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  20. Content type: Study protocol

    Physical activity (PA) and exercise have become an accepted and valued component of cystic fibrosis (CF) care. Regular PA and exercise can positively impact pulmonary function, improve physical fitness, and en...

    Authors: Helge Hebestreit, Larry C. Lands, Nancy Alarie, Jonathan Schaeff, Chantal Karila, David M. Orenstein, Don S. Urquhart, Erik H. J. Hulzebos, Lothar Stein, Christian Schindler, Susi Kriemler and Thomas Radtke

    Citation: BMC Pulmonary Medicine 2018 18:31

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  21. Content type: Research article

    Bronchial thermoplasty (BT) is a non-pharmacological intervention for severe asthma whose mechanism of action is not completely explained by a reduction of airway smooth muscle (ASM). In this study we analyzed...

    Authors: N. Facciolongo, A. Di Stefano, V. Pietrini, C. Galeone, F. Bellanova, F. Menzella, N. Scichilone, R. Piro, G. L. Bajocchi, B. Balbi, L. Agostini, P. P. Salsi, D. Formisano and M. Lusuardi

    Citation: BMC Pulmonary Medicine 2018 18:29

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  22. Content type: Research article

    Mortality is similarly high among individuals with usual interstitial pneumonia (UIP) due to idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia with autoimmune features (IPAF). Circulating anti-nuc...

    Authors: Justin M. Oldham, Leah J. Witt, Ayodeji Adegunsoye, Jonathan H. Chung, Cathryn Lee, Scully Hsu, Lena W. Chen, Aliya Husain, Steven Montner, Rekha Vij, Mary E. Strek and Imre Noth

    Citation: BMC Pulmonary Medicine 2018 18:30

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  23. Content type: Research article

    In the 1980s, randomized-controlled trials showed that high-dose corticosteroid treatment did not improve the mortality of acute respiratory distress syndrome (ARDS). However, while the diagnostic criteria for...

    Authors: Takashi Kido, Keiji Muramatsu, Takeshi Asakawa, Hiroki Otsubo, Takaaki Ogoshi, Keishi Oda, Tatsuhiko Kubo, Yoshihisa Fujino, Shinya Matsuda, Toshihiko Mayumi, Hiroshi Mukae and Kazuhiro Yatera

    Citation: BMC Pulmonary Medicine 2018 18:28

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  24. Content type: Research article

    The relationship of spirometric values to other respiratory and functional parameters in advanced age is not well studied. We assessed this relationship in elderly subjects with either good or poor spirometric...

    Authors: Stefan Karrasch, Jürgen Behr, Rudolf M. Huber, Dennis Nowak, Annette Peters, Stefan Peters, Rolf Holle, Rudolf A. Jörres and Holger Schulz

    Citation: BMC Pulmonary Medicine 2018 18:27

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