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  1. The study aimed to determine whether or notα7 nicotinic acetylcholine receptors (α7nAChR) induce anti-inflammatory effects directly in the lung or through the spleen pathway in a sterile model of lung injury b...

    Authors: Hossein Fatemikia, Amirreza Dehghanian, Bizhan Ziaian, Maryam Farokhipour and Farzaneh Ketabchi
    Citation: BMC Pulmonary Medicine 2022 22:367
  2. To compare treatment within 12 months of diagnosis, and survival by country of birth for people diagnosed with invasive non-small cell lung cancer (NSCLC) in New South Wales (NSW), Australia.

    Authors: Alana Little, David Roder, George W. Zhao, Sheetal Challam, Ashanya Malalasekera and David Currow
    Citation: BMC Pulmonary Medicine 2022 22:366
  3. Pulmonary alveolar proteinosis (PAP) is a rare clinical syndrome involving the accumulation of lipid-rich proteinaceous material in the alveoli. There is a paucity of published studies on this condition. To be...

    Authors: Chongiin Kim, Rodrigo Garcia-Tome, Carolina Hurtado, Li Ding, Tisha Wang and Ching-Fei Chang
    Citation: BMC Pulmonary Medicine 2022 22:365
  4. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is established as the preferred method of mediastinal lymph node (LN) staging in non-small cell lung cancer (NSCLC). Selective (targ...

    Authors: Daniel P. Steinfort, Shankar Siva, Kanishka Rangamuwa, Percy Lee, David Fielding, Phan Nguyen, Barton R. Jennings, Shaun Yo, Nick Hardcastle, Gargi Kothari, Laurence Crombag, Jouke Annema, Kazuhiro Yasufuku, David E. Ost and Louis B. Irving
    Citation: BMC Pulmonary Medicine 2022 22:364
  5. Difficult-to-control asthma associated with elevated body mass index (BMI) is challenging with limited treatment options. The effects of pulmonary rehabilitation (PR) in this population are uncertain.

    Authors: Helen Clare Ricketts, Varun Sharma, Femke Steffensen, Anna Goodfellow, Elaine Mackay, Gordon MacDonald, Duncan S. Buchan, Rekha Chaudhuri and Douglas C. Cowan
    Citation: BMC Pulmonary Medicine 2022 22:363
  6. Lymphangioleiomyomatosis (LAM) patients with severe lung disease may be considered for lung transplantation. Clinical, physiologic, and quality of life data are usually employed for referral. The aim of this s...

    Authors: Angelo M. Taveira-DaSilva, Vissaagan Gopalakrishnan, Jianhua Yao, Marcus Y. Chen, Patricia Julien-Williams, Amanda M. Jones, Gustavo Pacheco-Rodriguez and Joel Moss
    Citation: BMC Pulmonary Medicine 2022 22:362
  7. Transbronchial lung cryobiopsy is useful when diagnosing lung lesions. However, prevention of associated bleeding complications is essential. This study aimed to evaluate the safety and efficacy of our novel b...

    Authors: Masahide Oki, Hideo Saka, Yoshihito Kogure, Hideyuki Niwa, Akane Ishida, Arisa Yamada, Atsushi Torii and Chiyoe Kitagawa
    Citation: BMC Pulmonary Medicine 2022 22:361
  8. Lymphoepithelioma-like carcinoma (LELC) is a rare and unique subtype of cancer that histologically resembles undifferentiated nasopharyngeal carcinoma (NPC). The population-based analysis of LELC and the optim...

    Authors: Meiting Chen, Yungchang Chen, Xiaojie Fang, Zhao Wang, Xingxiang Pu, Chaoyong Liang, Hongqiang Guo, Qian Li, Fei Pan, Huangming Hong, He Huang, Jiman Li and Tongyu Lin
    Citation: BMC Pulmonary Medicine 2022 22:360
  9. Increased pleural fluid adenosine deaminase (ADA) is useful for diagnosing tuberculous pleurisy (TB), but high ADA levels are associated with other diseases. In this study, we compare various disease character...

    Authors: Masafumi Shimoda, Aya Hirata, Yoshiaki Tanaka, Kozo Morimoto, Takashi Yoshiyama, Kozo Yoshimori, Takeshi Saraya, Haruyuki Ishii and Ken Ohta
    Citation: BMC Pulmonary Medicine 2022 22:359
  10. Pleural infection is an infection of the pleural space that is usually treated with antibiotics and source control. Chest tube insertion is the most popular and widely used drainage technique. We typically att...

    Authors: Jumpei Taniguchi, Kei Nakashima, Hiroki Matsui, Tatsuya Nagai, Ayumu Otsuki, Hiroyuki Ito and Hiroshi Sugimura
    Citation: BMC Pulmonary Medicine 2022 22:358
  11. Discriminating asthma from chronic obstructive pulmonary disease (COPD) using medico-administrative databases is challenging but necessary for medico-economic analyses focusing on respiratory diseases. Artific...

    Authors: Hassan Joumaa, Raphaël Sigogne, Milka Maravic, Lucas Perray, Arnaud Bourdin and Nicolas Roche
    Citation: BMC Pulmonary Medicine 2022 22:357
  12. Sporadic lymphangioleiomyomatosis (S-LAM) is a rare neoplasm with heterogeneous clinical features that is conventionally considered to be related to TSC2. This study serves to elucidate the mutation landscape and...

    Authors: Jiannan Huang, Wenshuai Xu, Peng Liu, Yaping Liu, Cheng Shen, Song Liu, Yani Wang, Jun Wang, Tengyue Zhang, Yudi He, Chongsheng Cheng, Luning Yang, Weihong Zhang, Xinlun Tian and Kai-Feng Xu
    Citation: BMC Pulmonary Medicine 2022 22:354
  13. Although mean platelet volume (MPV) has been reported to be associated with poor prognosis of various critical illness, the relationship between MPV and in-hospital mortality among patients undergoing invasive...

    Authors: Yingying Zheng, Zujin Luo and Zhixin Cao
    Citation: BMC Pulmonary Medicine 2022 22:353
  14. The proportion of patients with obstructive sleep apnea–hypopnea syndrome (OSAHS) is increasing year by year in China, which has become a major public health problem. Self-management of OSAHS and multiple supp...

    Authors: Haitao Yu, Ye Gao, Tong Tong, Chunguang Liang, Hui Zhang, Xiangru Yan, Liying Wang, Huiying Zhang, Hongliang Dai and Huijuan Tong
    Citation: BMC Pulmonary Medicine 2022 22:352
  15. High flow nasal cannula (HFNC) is increasingly being used to support patients with acute respiratory failure (ARF) and to avoid need for intubation. However, almost one third of the patients do not respond and...

    Authors: Amit Kansal, Wei Jun Dan Ong, Shekhar Dhanvijay, Arbe Tisha Pepito Siosana, Loraine Mae Padillo, Chee Keat Tan, Monika Gulati Kansal and Faheem Ahmed Khan
    Citation: BMC Pulmonary Medicine 2022 22:350
  16. The optimal dose of glucocorticoids for acute respiratory distress syndrome (ARDS) is uncertain. This study aimed to evaluate the effects of different doses of methylprednisolone on sepsis-induced acute lung i...

    Authors: Shukun Hong, Chao Jian, Hongye Wang, Xincheng Wang, Luchuan Xing and Lujun Qiao
    Citation: BMC Pulmonary Medicine 2022 22:348
  17. Tracheal stent implantation is widely used in clinic settings. Timely removal of tracheal stents could prevent or reduce related complications. This study was aimed at evaluating the feasibility and safety of ...

    Authors: Pengfei Xie, Shuai Wang, Xiaobing Li, Ying Liu, Yaozhen Ma, Mei-Pan Yin, Xinwei Han and Gang Wu
    Citation: BMC Pulmonary Medicine 2022 22:344
  18. Emerging evidence shows that cardiovascular injuries and events in coronavirus disease 2019 (COVID-19) should be considered. The current study was conducted to develop an early prediction model for major adver...

    Authors: Dong Huang, Huan Yang, He Yu, Ting Wang, Zhu Chen, Rong Yao and Zongan Liang
    Citation: BMC Pulmonary Medicine 2022 22:343
  19. Physiotherapy-related data, such as airway clearance techniques (ACTS), physical activity and aerobic fitness are not consistently included in international cystic fibrosis (CF) data registries. This study aim...

    Authors: Angela Potter, Ben Singh, Emily Scutter and Carol Maher
    Citation: BMC Pulmonary Medicine 2022 22:342
  20. Different clinical predictors of physical activity (PA) have been described in idiopathic pulmonary fibrosis (IPF), but studies are lacking evaluating the potential role of muscle strength and anxiety and depr...

    Authors: Diana Badenes-Bonet, Anna Rodó-Pin, Diego Castillo-Villegas, Vanesa Vicens-Zygmunt, Guadalupe Bermudo, Fernanda Hernández-González, Karina Portillo, Juana Martínez-Llorens, Roberto Chalela, Oswaldo Caguana, Jacobo Sellarés, Maria Molina-Molina, Xavier Duran, Joaquim Gea, Diego Agustín Rodríguez-Chiaradia and Eva Balcells
    Citation: BMC Pulmonary Medicine 2022 22:340
  21. No consensus has been reached on an optimal blood lactate evaluation system although several approaches have been reported in the literature in recent years. A group-based trajectory modeling (GBTM) method cou...

    Authors: Haoyue Zhang, Ziping Li, Weiqiang Zheng, Linlin Zhang, Tianqi Yang, Keliang Xie and Yonghao Yu
    Citation: BMC Pulmonary Medicine 2022 22:339
  22. Although 20–60% of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have asthma, the risk factors associated with comorbid asthma are not clear. The aim of the study was to investigate the facto...

    Authors: Fangyuan Li, Xuechen Wang, Shen Shen, Kai Huang, Ming Wang, Xiaofang Liu, Chengshuo Wang, Jianmin Jin and Luo Zhang
    Citation: BMC Pulmonary Medicine 2022 22:338
  23. The optimum timing to wean is crucial to avoid negative outcomes for mechanically ventilated patients. The rapid shallow breathing index (RSBI), a widely used weaning index, has limitations in predicting weani...

    Authors: Jia Song, Zhixian Qian, Haixiang Zhang, Minjia Wang, Yihua Yu, Cong Ye, Weihang Hu and Shijin Gong
    Citation: BMC Pulmonary Medicine 2022 22:337
  24. Direct localization of small and deep pulmonary nodules before thoracoscopic surgery using the hookwire or methylene blue techniques has been recently attempted for better surgical outcomes. In this study, we ...

    Authors: Senlin Chu, Ning Wei, Dong Lu, Jie Chai, Shun Liu and Weifu Lv
    Citation: BMC Pulmonary Medicine 2022 22:336
  25. There are various reports on factors associated with physical activity in patients with chronic respiratory diseases. However, there are no studies on the relationship between physical activity and psychologic...

    Authors: Tomohiro Kawaji, Takashi Hasegawa and Yasushi Uchiyama
    Citation: BMC Pulmonary Medicine 2022 22:335
  26. Currently, the rate of morbidity and mortality in acute respiratory distress syndrome (ARDS) remains high. One of the potential reasons for the poor and ineffective therapies is the lack of early and credible ...

    Authors: Songchang Shi, Shuo Wei, Xiaobin Pan, Lihui Zhang, Shujuan Zhang, Xincai Wang, Songjing Shi and Wei Lin
    Citation: BMC Pulmonary Medicine 2022 22:334
  27. Human tumors are highly heterogeneous at the cellular, molecular, genetic and functional levels. Tumor heterogeneity has tremendous impact on cancer progression and treatment responses. However, the mechanisms...

    Authors: Dong Xia, Jieyi Liu, Juanjuan Yong, Xiang Li, Weidong Ji, Zhiqiang Zhao, Xiaohui Wang, Chen Xiao, Sai Wu, Huaixiang Liu, Heping Zhao and Yun He
    Citation: BMC Pulmonary Medicine 2022 22:333
  28. Due to the low efficiency of a single clinical feature or laboratory variable in the diagnosis of tuberculous pleural effusion (TBPE), the diagnosis of TBPE is still challenging. This study aimed to build a sc...

    Authors: Senquan Wu, Shaomei Li, Nianxin Fang, Weiliang Mo, Huadong Wang and Ping Zhang
    Citation: BMC Pulmonary Medicine 2022 22:332
  29. Pleural infection is a complex condition with a considerable healthcare burden. The average hospital stay for pleural infection is 14 days. Current standard of care defaults to chest tube insertion and intrave...

    Authors: David T. Arnold, Emma Tucker, Anna Morley, Alice Milne, Louise Stadon, Sonia Patole, George W. Nava, Steven P. Walker and Nick A. Maskell
    Citation: BMC Pulmonary Medicine 2022 22:330
  30. Idiopathic pulmonary fibrosis (IPF) often has significant diagnostic delay. At present it is not well-known what factors associate with time to diagnosis and if this is associated with survival after the diagn...

    Authors: T. W. Hoffman, H. W. van Es, D. H. Biesma and J. C. Grutters
    Citation: BMC Pulmonary Medicine 2022 22:329
  31. Lung nodule management remains a challenge to clinicians, especially in endemic tuberculosis areas. Different guidelines are available with various recommendations; however, the suitability of these guidelines...

    Authors: Norsyuhada Zaharudin, Mas Fazlin Mohamad Jailaini, Nik Nuratiqah Nik Abeed, Boon Hau Ng, Andrea Yu-Lin Ban, Mohd Imree, Rozman Zakaria, Syed Zulkifli Syed Zakaria and Mohamed Faisal Abdul Hamid
    Citation: BMC Pulmonary Medicine 2022 22:328
  32. Combined pulmonary fibrosis and emphysema (CPFE) is a novel clinical entity with a poor prognosis. This study aimed to develop a clinical nomogram model to predict the 1-, 2- and 3-year mortality of patients w...

    Authors: Qing Liu, Di Sun, Yu Wang, Pengfei Li, Tianci Jiang, Lingling Dai, Mengjie Duo, Ruhao Wu and Zhe Cheng
    Citation: BMC Pulmonary Medicine 2022 22:327
  33. The maximum gain in quality of life after lung transplantation (LT) is expected between six months and one year after LT, as the occurrence of chronic lung allograft dysfunction may mask the beneficial effects...

    Authors: Alexy Tran-Dinh, Donia Bouzid, Adnan El Kalai, Enora Atchade, Sébastien Tanaka, Brice Lortat-Jacob, Sylvain Jean-Baptiste, Nathalie Zappella, Sandrine Boudinet, Yves Castier, Hervé Mal, Pierre Mordant, Jonathan Messika and Philippe Montravers
    Citation: BMC Pulmonary Medicine 2022 22:326
  34. Birt-Hogg-Dubé syndrome (BHD) is an inherited disease caused by pathogenic variants in the FLCN gene. One of the characteristics is the increased risk for spontaneous pneumothorax, likely due to the presence of p...

    Authors: Jincey D. Sriram, Irma van de Beek, Paul C. Johannesma, Michiel H. van Werkum, Tijmen J. W. T. van der Wel, Elise M. Wessels, Hans J. J. P. Gille, Arjan C. Houweling, Pieter E. Postmus and Hans J. M. Smit
    Citation: BMC Pulmonary Medicine 2022 22:325
  35. N6-methyladenosine (m6A) is the most common RNA modification, which plays a pivotal role in tumor development and progression. In this study, we assessed the role of m6A methyltransferase METTL3 in FRAS1-invol...

    Authors: Xuejun Dou, Zhiyuan Wang, Weiqiang Lu, Libin Miao and Yuefeng Zhao
    Citation: BMC Pulmonary Medicine 2022 22:324
  36. The mortality rate remains high among patients with coinfection with Pneumocystis pneumonia (PCP) and HIV. The timing for initiation of antiretroviral therapy (ART) after a diagnosis of moderate to severe PCP rem...

    Authors: Yan-Ming Zeng, Yao Li, Yan-Qiu Lu, Min Liu, Jing-Min Nie, Jing Yuan, Vijay Harypursat, Yi-Hong Zhou, Yuan-Yuan Qin, Xiao-Hong Chen, Yu-Lin Zhang, De-Fa Zhang, Ni Wang, Hui Chen, Qun Tian, Yang Zhou…
    Citation: BMC Pulmonary Medicine 2022 22:323
  37. Peroxisomes are organelles that play essential roles in many metabolic processes, but also play roles in innate immunity, signal transduction, aging and cancer. One of the main functions of peroxisomes is the ...

    Authors: Jane S. Y. Sui, Petra Martin, Anna Keogh, Pierre Murchan, Lisa Ryan, Siobhan Nicholson, Sinead Cuffe, Pilib Ó Broin, Stephen P. Finn, Gerard J. Fitzmaurice, Ronan Ryan, Vincent Young and Steven G. Gray
    Citation: BMC Pulmonary Medicine 2022 22:321
  38. Chronic obstructive pulmonary disease (COPD) is one of the major health issues worldwide. Pathophysiological changes in COPD are mainly reflected in the deterioration of lung function with aging.

    Authors: Tieshan Wang, Zhaoqi Jia, Sen Li, Yuxin Li, Tingting Yu, Tao Lu and Yuanyuan Shi
    Citation: BMC Pulmonary Medicine 2022 22:320
  39. Electromagnetic navigation bronchoscopy (ENB) is an emerging advanced imaging-guided bronchoscopy technique for diagnosing peripheral lung lesions. However, the selection strategy for the optimal biopsy device...

    Authors: Yeon Wook Kim, Hyung-Jun Kim, Sung Hyun Yoon, Kyung Hee Lee, Young Mi Park, So Yeon Ahn, Myung Jin Song, Byoung Soo Kwon, Sung Yoon Lim, Yeon Joo Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Jae Ho Lee and Choon-Taek Lee
    Citation: BMC Pulmonary Medicine 2022 22:319
  40. The risk of developing lung cancer is increased in smokers, patients with chronic obstructive pulmonary disease, individuals exposed to environmental carcinogens, and those with a history of lung cancer. Autom...

    Authors: Hye Sook Choi and Ji-Youn Sung
    Citation: BMC Pulmonary Medicine 2022 22:318

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