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  1. Pulmonary Cryptococcosis is a common fungal infection mainly caused by Cryptococcus neoformans/C.gattii species in immunocompromised patients. Cases of pulmonary cryptococcosis in patients with normal immune func...

    Authors: Kelin Yao, Xiaofang Qiu, Hongjie Hu, Yuxin Han, Wenming Zhang, Ruiming Xia, Liang Wang and Jieming Fang

    Citation: BMC Pulmonary Medicine 2020 20:161

    Content type: Case report

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  2. Ceftriaxone (CTRX) and ampicillin/sulbactam (ABPC/SBT) are recommended by various guidelines as the first-line antibiotics for community-acquired pneumonia (CAP). However, which of these antibiotics is more ef...

    Authors: Nobuyoshi Hamao, Isao Ito, Satoshi Konishi, Naoya Tanabe, Masahiro Shirata, Issei Oi, Mitsuhiro Tsukino, Hisako Matsumoto, Yoshiro Yasutomo, Seizo Kadowaki and Toyohiro Hirai

    Citation: BMC Pulmonary Medicine 2020 20:160

    Content type: Research article

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  3. Whereas Burkholderia infections are recognized to impair prognosis in cystic fibrosis (CF) patients, there is no recommendation to date for early eradication therapy. The aim of our study was to analyse the curre...

    Authors: Vianney Gruzelle, Hélène Guet-Revillet, Christine Segonds, Stéphanie Bui, Julie Macey, Raphaël Chiron, Marine Michelet, Marlène Murris-Espin and Marie Mittaine

    Citation: BMC Pulmonary Medicine 2020 20:159

    Content type: Research article

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  4. Lung cancer is frequently situated peripherally in the upper lobes of the lung. Acquiring adequate tissue from this difficult-to-reach area remains a challenge. Transbronchial cryobiopsy (TBCB) has the ability...

    Authors: Sze Shyang Kho, Chan Sin Chai, Larry Ellee Nyanti, Adam Malik bin Ismail and Siew Teck Tie

    Citation: BMC Pulmonary Medicine 2020 20:158

    Content type: Case report

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  5. Obstructive sleep apnoea (OSA) is related with adverse pregnancy outcomes, including preeclampsia. However, there are small studies about treatment of OSA with automatic continuous positive airway pressure (CP...

    Authors: Mi Sun Kim, Myoung Jin Moon, Yoon Hee Lee, Kyu Young Chae and Eun Hee Ahn

    Citation: BMC Pulmonary Medicine 2020 20:157

    Content type: Case report

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  6. Statin-associated necrotizing myopathy (SANM) is a rare autoimmune disorder caused by administration of statins. SANM is characterized by weakness due to necrosis and regeneration of myofibers. Here we report ...

    Authors: Yuriko Yamamura, Yoshinori Matsumoto, Koh Tadokoro, Yasuyuki Ohta, Kota Sato, Toru Yamashita, Masahiro Yamamura, Ken-Ei Sada, Koji Abe and Jun Wada

    Citation: BMC Pulmonary Medicine 2020 20:156

    Content type: Case report

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  7. Macitentan is a dual endothelin receptor antagonist indicated for the long-term treatment of pulmonary arterial hypertension (PAH). We evaluated the change over time in REVEAL risk score in incident and preval...

    Authors: Pilar Escribano-Subias, Raquel López, Luis Almenar, María Lázaro, Ian Forn, Anna Torrent, Isabel Blanco and Joan Albert Barberà

    Citation: BMC Pulmonary Medicine 2020 20:154

    Content type: Research article

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  8. Sarcoidosis is a systemic granulomatous disease of unknown etiology. Clinical cohort studies of different populations are important to understand the high variability in clinical presentation and disease cours...

    Authors: Hok Sreng Te, David M. Perlman, Chetan Shenoy, Daniel J. Steinberger, Rebecca J. Cogswell, Henri Roukoz, Erik J. Peterson, Lin Zhang, Tadashi L. Allen and Maneesh Bhargava

    Citation: BMC Pulmonary Medicine 2020 20:155

    Content type: Research article

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  9. Long non-coding RNA (lncRNA) Wilms Tumor 1 Associated Protein Pseudogene 1 (WTAPP1) has been reported to be a critical player in the angiogenesis and migration of endothelial progenitor cells, while its involv...

    Authors: Li Zhang, Chengyan Jin, Guiyun Yang, Bin Wang, Peiyan Hua and Yan Zhang

    Citation: BMC Pulmonary Medicine 2020 20:153

    Content type: Research article

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  10. Usual clinical practice for arterial blood gas analysis (BGA) in conscious patients involves a one-time arterial puncture to be performed after a resting period of 20–30 min. The aim of this study was to evalu...

    Authors: Akira Umeda, Masahiro Ishizaka, Masamichi Tasaki, Tateki Yamane, Taiji Watanabe, Yasushi Inoue, Taichi Mochizuki, Yasumasa Okada and Sarah Kesler

    Citation: BMC Pulmonary Medicine 2020 20:151

    Content type: Research article

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  11. Variants in the gene encoding bone morphogenetic protein receptor type II (BMPR2) are the most common genetic cause of pulmonary arterial hypertension (PAH), whereas biallelic variants in the eukaryotic translati...

    Authors: Qixian Zeng, Hang Yang, Bingyang Liu, Yanyun Ma, Zhihong Liu, Qianlong Chen, Wenke Li, Qin Luo, Zhihui Zhao, Zhou Zhou and Changming Xiong

    Citation: BMC Pulmonary Medicine 2020 20:150

    Content type: Research article

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  12. Vascular Ehlers-Danlos syndrome (vEDS) is a rare autosomal dominant hereditary collagen disease caused by a defect or deficiency in the pro-α1 chain of type III procollagen encoded by the COL3A1 gene. Patients...

    Authors: Tingting Wan, Jinyan Ye, Peiliang Wu, Mengshi Cheng, Baihong Jiang, Hailong Wang, Jianmin Li, Jun Ma, Liangxing Wang and Xiaoying Huang

    Citation: BMC Pulmonary Medicine 2020 20:149

    Content type: Case report

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  13. Forced expiratory volume in one second (FEV1) characterizes the pathophysiology of COPD and different trajectories of FEV1 decline have been observed in patients with COPD (e.g. gradual or episodic). There is lim...

    Authors: Johanna I. Lutter, Rudolf A. Jörres, Kathrin Kahnert, Larissa Schwarzkopf, Michael Studnicka, Stefan Karrasch, Holger Schulz, Claus F. Vogelmeier and Rolf Holle

    Citation: BMC Pulmonary Medicine 2020 20:148

    Content type: Research article

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  14. We assessed the rate of and predictors for all-cause mortality in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) receiving plasma exchange (PLEX) and evaluated the surviva...

    Authors: Pil Gyu Park, Byung-Woo Yoo, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee

    Citation: BMC Pulmonary Medicine 2020 20:147

    Content type: Research article

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  15. Pulmonary tuberculosis is one of the most common infectious diseases worldwide. Patients with suspected pulmonary tuberculosis with negative smear are recommended to undergo further tests including sputum indu...

    Authors: Wen Luo, Yihua Lin, Zhibin Li, Wanyu Wang and Yonghong Shi

    Citation: BMC Pulmonary Medicine 2020 20:146

    Content type: Research article

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  16. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Smita Pakhale, Michael Armstrong, Crystal Holly, Rojiemiahd Edjoc, Ena Gaudet, Shawn Aaron, Giorgio Tasca, William Cameron and Louise Balfour

    Citation: BMC Pulmonary Medicine 2020 20:145

    Content type: Correction

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    The original article was published in BMC Pulmonary Medicine 2014 14:76

  17. Previous analyses of combined pulmonary fibrosis and emphysema (CPFE) cohorts have provided conflicting data on the survival of patients with CPFE. Therefore, the aim of this study was to investigate the clini...

    Authors: Yuichi Ikuyama, Atsuhito Ushiki, Makoto Kosaka, Jumpei Akahane, Yuichi Mukai, Taisuke Araki, Yoshiaki Kitaguchi, Kazunari Tateishi, Kazuhisa Urushihata, Masanori Yasuo, Hiroshi Yamamoto and Masayuki Hanaoka

    Citation: BMC Pulmonary Medicine 2020 20:144

    Content type: Research article

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  18. Supervised cardio-pulmonary rehabilitation may be safe and beneficial for people with pulmonary hypertension (PH) in groups 1 (pulmonary arterial hypertension) and 4 (chronic thromboembolic disease), particula...

    Authors: Gordon McGregor, Julie Bruce, Stuart Ennis, James Mason, Ranjit Lall, Chen Ji, Harbinder Sandhu, Kate Seers, Prithwish Banerjee, Alastair Canaway, Katie Booth, Stephanie J. C. Taylor, Elizabeth Robertson, Tamar Pincus, Sally Singh, David Fitzmaurice…

    Citation: BMC Pulmonary Medicine 2020 20:143

    Content type: Study protocol

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  19. Attenuated decreases in lung function can signal the onset of acute respiratory events known as pulmonary exacerbations (PEs) in children and adolescents with cystic fibrosis (CF). Univariate joint modeling fa...

    Authors: E. R. Andrinopoulou, J. P. Clancy and R. D. Szczesniak

    Citation: BMC Pulmonary Medicine 2020 20:142

    Content type: Research article

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  20. Primary Ciliary Dyskinesia (PCD) is also known as immotile-cilia syndrome, an autosomal recessive disorder of ciliary function, leading to mucus retention in the respiratory system in childhood. Our knowledge ...

    Authors: Fuad Al Mutairi, Randa Alkhalaf, Abdullah Alkhorayyef, Fayhan Alroqi, Alyafee Yusra, Muhammad Umair, Fetaini Nouf, Amjad Khan, Alharbi Meshael, Aleidi Hamad, Alaujan Monira, Abdulaziz Asiri, Kheloud M. Alhamoudi and Majid Alfadhel

    Citation: BMC Pulmonary Medicine 2020 20:141

    Content type: Case report

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  21. Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) has been become an important procedure for the diagnosis and staging of lung cancer. Our research identified the effects of differen...

    Authors: Youzu Xu, Jian Lin, Meifang Chen, Haihong Zheng and Jiaxi Feng

    Citation: BMC Pulmonary Medicine 2020 20:140

    Content type: Research article

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  22. Asthma is a complex syndrome with multiple domains including symptoms, lung function, asthma control, and airway inflammation. A study of Fenom PRO™, a novel monitor for exhaled nitric oxide (FeNO), provided a...

    Authors: Philip E. Silkoff, Mark Sarno, Solomon Ssenyange, Vivek Balasubramanyam, Brian Awabdy and Ryan Leard

    Citation: BMC Pulmonary Medicine 2020 20:139

    Content type: Research article

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  23. Fluoroquinolones (FQs) are potential drugs that inhibit DNA synthesis and are used in the treatment of multidrug-resistant tuberculosis (TB) and short-term anti-TB regimens. In recent years, a high proportion ...

    Authors: Saba Kabir, Zarfishan Tahir, Nadia Mukhtar, Muhammad Sohail, Muhammad Saqalein and Abdul Rehman

    Citation: BMC Pulmonary Medicine 2020 20:138

    Content type: Research article

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  24. The association between chronic obstructive pulmonary disease (COPD), lung function and risk of type 2 diabetes mellitus (T2DM) remains controversial. We performed a meta-analysis to clarify this issue.

    Authors: Yang Peng, Guo-Chao Zhong, Lingxiao Wang, Lijuan Guan, Ao Wang, Kai Hu and Jing Shen

    Citation: BMC Pulmonary Medicine 2020 20:137

    Content type: Research article

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  25. Patients with a primary spontaneous pneumothorax (PSP) who are treated with chest tube drainage are traditionally connected to an analogue chest drainage system, containing a water seal and using a visual meth...

    Authors: Dieuwertje Ruigrok, Peter W. A. Kunst, Marielle M. J. Blacha, Ben Tomlow, Jacobine W. Herbrink, Eva J. Japenga, Wim Boersma, Paul Bresser, Ivo van der Lee and Kris Mooren

    Citation: BMC Pulmonary Medicine 2020 20:136

    Content type: Research article

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  26. Revefenacin, a once-daily, long-acting muscarinic antagonist delivered via standard jet nebulizer, increased trough forced expiratory volume in 1 s (FEV1) in patients with moderate to very severe chronic obstruct...

    Authors: James F. Donohue, Edward Kerwin, Chris N. Barnes, Edmund J. Moran, Brett Haumann and Glenn D. Crater

    Citation: BMC Pulmonary Medicine 2020 20:134

    Content type: Research article

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  27. COPD exacerbations have negative impact on patients’ survival. Several risk factors for grave outcomes of such exacerbations have been descried. Muscle dysfunction and mass loss were shown to impact negatively...

    Authors: N. Lasman, M. Shalom, N. Turpashvili, G. Goldhaber, Y. Lifshitz, E. Leibowitz, G. Berger, G. Saltzman-Shenhav, A. Brom, D. Cohen, C. Avaky and G. Segal

    Citation: BMC Pulmonary Medicine 2020 20:133

    Content type: Research article

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  28. Following publication of the original article [1], the authors have flagged that there is an error in Fig. 3.

    Authors: Takumi Yoshikawa, Mitsuo Otsuka, Hirofumi Chiba, Kimiyuki Ikeda, Yuki Mori, Yasuaki Umeda, Hirotaka Nishikiori, Koji Kuronuma and Hiroki Takahashi

    Citation: BMC Pulmonary Medicine 2020 20:131

    Content type: Correction

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    The original article was published in BMC Pulmonary Medicine 2020 20:27

  29. Home mechanical ventilation is a reliable treatment for patients suffering from chronic respiratory failure, improving survival and quality of life. Prevalence has been increasing worldwide as a result of evol...

    Authors: Luca Valko, Szabolcs Baglyas, Laszlo Kunos, Attila Terray-Horvath, Andras Lorx, Janos Gal and Wolfram Windisch

    Citation: BMC Pulmonary Medicine 2020 20:130

    Content type: Research article

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  30. Although typical and atypical CT image findings of COVID-19 are reported in current studies, the CT image features of COVID-19 overlap with those of viral pneumonia and other respiratory diseases. Hence, it is...

    Authors: Lin Luo, Zhendong Luo, Yizhen Jia, Cuiping Zhou, Jianlong He, Jianxun Lyu and Xinping Shen

    Citation: BMC Pulmonary Medicine 2020 20:129

    Content type: Research article

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  31. While antifibrotic drugs significantly decrease lung function decline in idiopathic pulmonary fibrosis (IPF), there is still an unmet need to halt disease progression. Antioxidative therapy with N-acetylcystei...

    Authors: Hanyu Shi, Dawei Yin, Francesco Bonella, Michael Kreuter, Ute Oltmanns, Xuren Li, Shouchun Peng and Luqing Wei

    Citation: BMC Pulmonary Medicine 2020 20:128

    Content type: Research article

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  32. Pulmonary tuberculosis (PTB) is frequently associated with chronic respiratory impairment despite microbiological cure. There are only a few clinical research studies that describe the course, type and severit...

    Authors: Celso Khosa, Nilesh Bhatt, Isabel Massango, Khalide Azam, Elmar Saathoff, Abhishek Bakuli, Friedrich Riess, Olena Ivanova, Michael Hoelscher and Andrea Rachow

    Citation: BMC Pulmonary Medicine 2020 20:127

    Content type: Research article

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  33. Improvement in health-related quality of life (HRQL) has been suggested as an alternative treatment goal of non-tuberculous mycobacterial pulmonary disease (NTM-PD). This study was performed to elucidate the l...

    Authors: Nakwon Kwak, Sung A Kim, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee and Jae-Joon Yim

    Citation: BMC Pulmonary Medicine 2020 20:126

    Content type: Research article

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  34. High-concentration oxygen therapy causes increased arterial partial pressure of carbon dioxide (PaCO2) in patients with COPD, asthma, pneumonia, obesity and acute lung injury. The objective of these studies was t...

    Authors: Janine Pilcher, Darmiga Thayabaran, Stefan Ebmeier, Mathew Williams, Geraldine Back, Hamish Collie, Michael Richards, Susan Bibby, Ruth Semprini, Mark Weatherall and Richard Beasley

    Citation: BMC Pulmonary Medicine 2020 20:125

    Content type: Research article

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  35. Extracorporeal membrane oxygenation (ECMO) has been increasingly used for severe neonatal respiratory failure refractory to conventional treatments. To systematically evaluate the complications and mortality o...

    Authors: Jing Xiong, Li Zhang and Lei Bao

    Citation: BMC Pulmonary Medicine 2020 20:124

    Content type: Research article

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  36. Previous studies have established a higher prevalence of vitamin D deficiency in patients with COPD, but the relationship between vitamin D levels and COPD exacerbations remains controversial. In addition, the...

    Authors: Auyon J. Ghosh, Matthew Moll, Lystra P. Hayden, Jessica Bon, Elizabeth Regan and Craig P. Hersh

    Citation: BMC Pulmonary Medicine 2020 20:123

    Content type: Research article

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  37. Pirfenidone is an antifibrotic agent approved for the treatment of idiopathic pulmonary fibrosis (IPF). The drug is available for Polish patients with IPF since 2017. The PolExPIR study aimed to describe the r...

    Authors: Sebastian Majewski, Adam J. Białas, Małgorzata Buchczyk, Paweł Gomółka, Katarzyna Górska, Hanna Jagielska-Len, Agnieszka Jarzemska, Ewa Jassem, Dariusz Jastrzębski, Aleksander Kania, Marek Koprowski, Rafał Krenke, Jan Kuś, Katarzyna Lewandowska, Magdalena M. Martusewicz-Boros, Kazimierz Roszkowski-Śliż…

    Citation: BMC Pulmonary Medicine 2020 20:122

    Content type: Research article

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  38. An asymptomatic SCUBA (Self-contained underwater breathing apparatus) diver was discovered to have an intralobar bronchopulmonary sequestration during routine pre-course screening. This is the first reported c...

    Authors: Timothy Xin Zhong Tan, Andrew Yunkai Li, James Jie Sng, Mark Lim, Zhi Xiang Tan, Hope Xian’en Ang, Boon Hor Ho, David Zhiwei Law and Anne Ann Ling Hsu

    Citation: BMC Pulmonary Medicine 2020 20:121

    Content type: Case report

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  39. Although many studies on people with Chronic Obstructive Pulmonary Disease (COPD) have examined the mutual impact of physical status and emotional experience, there is limited knowledge about the way COPD peop...

    Authors: Marta Pozzar, Eleonora Volpato, Chiara Valota, Francesco Pagnini and Paolo Innocente Banfi

    Citation: BMC Pulmonary Medicine 2020 20:120

    Content type: Research article

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  40. Batefenterol (BAT) is a bi-functional molecule with both muscarinic antagonist and β2-adrenoceptor agonist pharmacology. This Phase II, randomized, placebo-controlled, double-blind study evaluated the safety and ...

    Authors: Courtney Crim, Mark Gotfried, Selwyn Spangenthal, Michael Watkins, Amanda Emmett, Catriona Crawford, Charlotte Baidoo and Ramiro Castro-Santamaria

    Citation: BMC Pulmonary Medicine 2020 20:119

    Content type: Research article

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  41. Electronic cigarettes/e-cigarettes (ECs), or vaping, is currently the most popular form of smoking amongst youth in the United States. ECs are battery-powered devices that vaporize a liquid that comes in small...

    Authors: Andrew L. Silverman, Haseeb Siddique, Vikas Kumar, Thuy-Hong Le and Joseph Ng

    Citation: BMC Pulmonary Medicine 2020 20:118

    Content type: Research article

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  42. Various host factors can promote pneumonia susceptibility of lung cancer patients. However, data about risk factors for pneumonia in lung cancer patients receiving active treatments such as chemotherapy, radio...

    Authors: Jung Won Heo, Chang Dong Yeo, Chan Kwon Park, Sung Kyoung Kim, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Sang Haak Lee and Hye Seon Kang

    Citation: BMC Pulmonary Medicine 2020 20:117

    Content type: Research article

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  43. Pulmonary cryptococcosis is an uncommon infectious disease that can develop in both immunocompromised and immunocompetent patients. The severity of chronic kidney disease (CKD) was reported to be one of the ri...

    Authors: Hiroki Tashiro, Tetsuro Haraguchi, Koichiro Takahashi, Hironori Sadamatsu, Ryo Tajiri, Ayako Takamori, Shinya Kimura and Naoko Sueoka-Aragane

    Citation: BMC Pulmonary Medicine 2020 20:116

    Content type: Research article

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  44. Appropriate management of lung nodules detected incidentally or through lung cancer screening can increase the rate of early-stage diagnoses and potentially improve treatment outcomes. However, the implementat...

    Authors: Gregory P. LeMense, Ernest A. Waller, Cheryl Campbell and Tyler Bowen

    Citation: BMC Pulmonary Medicine 2020 20:115

    Content type: Research article

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  45. Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial. This study analysed pulmonary function ...

    Authors: Liangmei Chen, Xiaomin Liu, Qian Wang, Linpei Jia, Kangkang Song, Sasa Nie, Yinping Zhang, Dan Cao, Delong Zhao, Zuoxiang Li, Zheyi Dong, Ying Zheng, Shuwei Duan, Xuefeng Sun, Zhe Feng, Guangyan Cai…

    Citation: BMC Pulmonary Medicine 2020 20:114

    Content type: Research article

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