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  1. Content type: Research article

    Vitamin D deficiency has been linked to an increased risk of asthma. This study aimed to quantify the effect of early life vitamin D status on asthma and wheeze later in life.

    Authors: Song-Ying Shen, Wan-Qing Xiao, Jin-Hua Lu, Ming-Yang Yuan, Jian-Rong He, Hui-Min Xia, Xiu Qiu, Kar Keung Cheng and Kin Bong Hubert Lam

    Citation: BMC Pulmonary Medicine 2018 18:120

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  2. Content type: Case report

    Crizotinib is a multi-target inhibitor approved for the treatment of advanced non-small-cell lung cancer patients with a ROS1 rearrangement. However, interstitial lung disease is a rare but severe and fatal si...

    Authors: Shibo Wu, Kaitai Liu, Feng Ren, Dawei Zheng and Deng Pan

    Citation: BMC Pulmonary Medicine 2018 18:121

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  3. Content type: Research article

    Interleukin-5 (IL-5) antibodies represent a promising therapeutic option for patients with severe eosinophilic asthma. To date, no official treatment response criteria exist. In this study, simple criteria for...

    Authors: Nora Drick, Benjamin Seeliger, Tobias Welte, Jan Fuge and Hendrik Suhling

    Citation: BMC Pulmonary Medicine 2018 18:119

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  4. Content type: Research article

    It is widely accepted that exercise capacity in healthy individuals is limited by the cardiac function, while the respiratory system is considered oversized. Although there is physiological, age-related declin...

    Authors: Amir Farkhooy, Johan Bodegård, Jan Erik Erikssen, Christer Janson, Hans Hedenström, Knut Stavem and Andrei Malinovschi

    Citation: BMC Pulmonary Medicine 2018 18:118

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  5. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality around the world. The aim of our study was to determine the association between specific comorbidities and COPD sev...

    Authors: Chantal Raherison, El-Hassane Ouaalaya, Alain Bernady, Julien Casteigt, Cecilia Nocent-Eijnani, Laurent Falque, Frédéric Le Guillou, Laurent Nguyen, Annaig Ozier and Mathieu Molimard

    Citation: BMC Pulmonary Medicine 2018 18:117

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  6. Content type: Research article

    Prognostic stratification of elderly patients with chronic obstructive pulmonary disease (COPD) is difficult due to the wide inter-individual variability in the course of the disease. No marker can exactly str...

    Authors: Domenico Acanfora, Pietro Scicchitano, Mauro Carone, Chiara Acanfora, Giuseppe Piscosquito, Roberto Maestri, Annapaola Zito, Ilaria Dentamaro, Marialaura Longobardi, Gerardo Casucci, Raffaele Antonelli-Incalzi and Marco Matteo Ciccone

    Citation: BMC Pulmonary Medicine 2018 18:116

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  7. Content type: Research article

    Pulmonary Mycobacterium avium complex (pMAC) disease is a chronic, slowly progressive disease. The aim of the present study was to determine the association of six-minute walk test (6MWT) parameters with pulmonar...

    Authors: Kazuma Yagi, Takanori Asakura, Ho Namkoong, Shoji Suzuki, Takahiro Asami, Satoshi Okamori, Tatsuya Kusumoto, Yohei Funatsu, Hirofumi Kamata, Tomoyasu Nishimura, Makoto Ishii, Tomoko Betsuyaku and Naoki Hasegawa

    Citation: BMC Pulmonary Medicine 2018 18:114

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  8. Content type: Research article

    Sputum induction is an important noninvasive method for analyzing bronchial inflammation in patients with asthma and other respiratory diseases. Most frequently, ultrasonic nebulizers are used for sputum induc...

    Authors: Sinem Koc-Günel, Ralf Schubert, Stefan Zielen and Martin Rosewich

    Citation: BMC Pulmonary Medicine 2018 18:115

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  9. Content type: Research article

    The natural history of airway inflammation and symptoms in occupations at risk of asthma is still not fully understood. We aimed to study the evolution during apprenticeship of inflammation markers, bronchial ...

    Authors: Valérie Demange, Denis Zmirou-Navier, Abraham Bohadana and Pascal Wild

    Citation: BMC Pulmonary Medicine 2018 18:113

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  10. Content type: Case report

    Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare cause of pulmonary hypertension that is associated with malignancies and is marked by the presence of non-occlusive tumor emboli and fibrocellular in...

    Authors: Dante A. Suffredini, Jung-Min Lee, Cody J. Peer, Drew Pratt, David E. Kleiner, Jason M. Elinoff and Michael A. Solomon

    Citation: BMC Pulmonary Medicine 2018 18:112

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  11. Content type: Research article

    Pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is suggested as the consequence of emphysematous destruction of vascular bed and hypoxia of pulmonary microenvironment, mechanisms un...

    Authors: Xiaotong Guo, Yuchun Fan, Jieda Cui, Binwei Hao, Li Zhu, Xiao Sun, Jinxi He, Jiali Yang, Jianda Dong, Yanyang Wang, Xiaoming Liu and Juan Chen

    Citation: BMC Pulmonary Medicine 2018 18:111

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  12. Content type: Research article

    In the Commonwealth of Independent States (CIS) countries epidemiology of Bronchial Asthma (BA) is poorly characterized. The objective of this analysis is to present the prevalence, burden and risk factors ass...

    Authors: Damilya Nugmanova, Lyudmila Sokolova, Yuriy Feshchenko, Liudmila Iashyna, Olga Gyrina, Katerina Malynovska, Ilgar Mustafayev, Gulzar Aliyeva, Janina Makarova, Averyan Vasylyev and Luqman Tariq

    Citation: BMC Pulmonary Medicine 2018 18:110

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  13. Content type: Research article

    Multiple factors are involved in asthma exacerbations, including environmental exposure and viral infections. We aimed to assess the association between severe asthma exacerbations, acute respiratory viral inf...

    Authors: Lusmaia Damaceno Camargo Costa, Paulo Augusto Moreira Camargos, Paul L. P. Brand, Fabíola Souza Fiaccadori, Menira Borges de Lima Dias e Souza, Divina das Dôres de Paula Cardoso, Ítalo de Araújo Castro, Ruth Minamisava and Paulo Sérgio Sucasas da Costa

    Citation: BMC Pulmonary Medicine 2018 18:109

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  14. Content type: Research article

    Incorrect inhaler technique is a common cause of poor asthma control. This two-phase pragmatic study evaluated inhaler technique mastery and maintenance of mastery with DuoResp® (budesonide-formoterol [BF]) Sp...

    Authors: David B. Price, Vicky Thomas, P. N. Richard Dekhuijzen, Sinthia Bosnic-Anticevich, Nicolas Roche, Federico Lavorini, Priyanka Raju, Daryl Freeman, Carole Nicholls, Iain R. Small, Erika Sims, Guilherme Safioti, Janice Canvin and Henry Chrystyn

    Citation: BMC Pulmonary Medicine 2018 18:107

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  15. Content type: Research article

    Vitamin D is involved in the host immune response toward Mycobacterium tuberculosis. However, the efficacy of vitamin D supplementation on sputum conversion, clinical response to treatment, adverse events, and mo...

    Authors: Hong-xia Wu, Xiao-feng Xiong, Min Zhu, Jia Wei, Kai-quan Zhuo and De-yun Cheng

    Citation: BMC Pulmonary Medicine 2018 18:108

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  16. Content type: Research article

    Pulmonary arterial hypertension is a rare, progressive disease with poor prognosis. However, there is limited information available on the characteristics of PAH patients outside of North America and Europe. T...

    Authors: Ana Beatriz Valverde, Juliana M. Soares, Karynna P. Viana, Bruna Gomes, Claudia Soares and Rogerio Souza

    Citation: BMC Pulmonary Medicine 2018 18:106

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  17. Content type: Research article

    Cystic fibrosis (CF) is associated with bacterial pulmonary infections and neutrophil-dominated inflammation in the airways. The aim of this study was to evaluate the neutrophil-derived protein Heparin-binding...

    Authors: Gisela Hovold, Victoria Palmcrantz, Fredrik Kahn, Arne Egesten and Lisa I. Påhlman

    Citation: BMC Pulmonary Medicine 2018 18:104

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  18. Content type: Research article

    “Velcro-type” crackles on chest auscultation are considered a typical acoustic finding of Fibrotic Interstitial Lung Disease (FILD), however whether they may have a role in the early detection of these disorde...

    Authors: Giacomo Sgalla, Simon L. F. Walsh, Nicola Sverzellati, Sophie Fletcher, Stefania Cerri, Borislav Dimitrov, Dragana Nikolic, Anna Barney, Fabrizio Pancaldi, Luca Larcher, Fabrizio Luppi, Mark G. Jones, Donna Davies and Luca Richeldi

    Citation: BMC Pulmonary Medicine 2018 18:103

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  19. Content type: Research article

    The ability of circulating monocytes to develop into lung macrophages and promote lung tissue damage depends upon their phenotypic pattern of differentiation and activation. Whether this phenotypic pattern var...

    Authors: William D. Cornwell, Victor Kim, Xiaoxuan Fan, Marie Elena Vega, Frederick V. Ramsey, Gerard J. Criner and Thomas J. Rogers

    Citation: BMC Pulmonary Medicine 2018 18:101

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  20. Content type: Research article

    Regular airway clearance by chest physiotherapy and/or exercise is critical to lung health in cystic fibrosis (CF). Combination of cycling exercise and chest physiotherapy using the Flutter® device on sputum p...

    Authors: Thomas Radtke, Lukas Böni, Peter Bohnacker, Marion Maggi-Beba, Peter Fischer, Susi Kriemler, Christian Benden and Holger Dressel

    Citation: BMC Pulmonary Medicine 2018 18:99

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  21. Content type: Research article

    The chronic and progressive nature of chronic obstructive pulmonary disease (COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are increasingly being used for inhalation ther...

    Authors: Pablo Altman, Luis Wehbe, Juergen Dederichs, Tadhg Guerin, Brian Ament, Miguel Cardenas Moronta, Andrea Valeria Pino and Pankaj Goyal

    Citation: BMC Pulmonary Medicine 2018 18:100

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  22. Content type: Research article

    The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or w...

    Authors: Shilpa Dogra, Joshua Good, Matthew P. Buman, Paul A. Gardiner, Jennifer L. Copeland and Michael K. Stickland

    Citation: BMC Pulmonary Medicine 2018 18:98

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