Table 4 Incidence of most common adverse events (safety population)
No. (%) of Subjects [No. of Events] | ||||
|---|---|---|---|---|
CAT-354 | ||||
1 mg/kg (n = 8) | 5 mg/kg (n = 8) | 10 mg/kg (n = 3) | Placebo (n = 4) | |
Nasopharyngitis | 5 (62.5) [6] | 7 (87.5) [10] | 2 (66.7) [2] | 3 (75.0) [4] |
Headache | 3 (37.5) [3] | 4 (50.0) [6] | 1 (33.3) [1] | 2 (50.0) [4] |
Lower respiratory tract infection | 1 (12.5) [1] | 1 (12.5) [1] | 0 | 1 (25.0) [2] |
Cough | 1 (12.5) [1] | 1 (12.5) [1] | 0 | 1 (25.0) [1] |
Pharyngolaryngeal pain | 0 | 1 (12.5) [1] | 1 (33.3) [2] | 0 |
Pain | 1 (12.5) [1] | 1 (12.5) [1] | 0 | 0 |
Chest discomfort | 0 | 0 | 1 (33.3) [1] | 1 (25.0) [1] |
Diarrhoea | 1 (12.5) [1] | 1 (12.5) [1] | 0 | 0 |