Table 2 Baseline Pulmonary Function of IPF Patients According to FcγRIIa Genotypes
FcγRIIa Genotype | ||||
|---|---|---|---|---|
RR | RH | HH | Pvalue | |
Patients, n | 53 | 61 | 28 | |
Age, y | 70.1 ± 8.9 | 70.1 ± 8.9 | 69.8 ± 10.5 | NS |
FEV 1 , L | 2.31 ± 0.6 | 2.12 ± 0.6 | 1.96 ± 0.5 | 0.037 |
% predicted | 93.0 ± 22.0 | 85.7 ± 17.4 | 81.5 ± 19.4 | 0.031 |
FVC, L | 2.92 ± 0.8 | 2.75 ± 0.8 | 2.43 ± 0.6 | 0.026 |
% predicted | 91.9 ± 20.6 | 87.1 ± 17.4 | 80.1 ± 20.7 | 0.041 |
FEV 1 /VC, % predicted | 79.7 ± 9.4 | 77.5 ± 10.2 | 81.3 ± 9.7 | NS |
TLC, L | 4.47 ± 0.9 | 4.82 ± 1.1 | 3.94 ± 1.0 | NS |
% predicted | 76.7 ± 14.0 | 72.9 ± 15.8 | 71.8 ± 16.5 | NS |
D L CO , ml/min/mmHg | 4.49 ± 1.4 | 3.98 ± 1.2 | 3.54 ± 1.4 | 0.012 |
% predicted | 57.4 ± 15.4 | 51.4 ± 15.0 | 45.7 ± 16.4 | 0.007 |
K CO , ml/min/mmHg/L | 1.17 ± 0.3 | 1.07 ± 0.3 | 1.06 ± 0.3 | NS |
% predicted | 87.6 ± 24.6 | 80.1 ± 20.5 | 76.6 ± 22.9 | NS |