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Table 1 Baseline characteristics of patients

From: The impact of obesity on walking and cycling performance and response to pulmonary rehabilitation in COPD

  Normal BMI Overweight Obese ANOVA
  n = 88 n = 95 n = 78 p-value
Age, years 66.0 ± 9.4 65.7 ± 8.2 65.4 ± 8.0 NS
Sex, % of men 56 61 59 NS
Body mass index, kg/m2 22.3 ± 1.8* 27.5 ± 1.5* 35.1 ± 3.5 <0.001
Height (cm) 164 ± 9.1 165 ± 9.2 163 ± 9.8 NS
Weight (kg) 61 ± 8.6* 75 ± 9.8* 91 ± 14.6 <0.001
BODE score 3.9 ± 2.0* 3.1 ± 2.0 3.2 ± 2.4 0.002
Pulmonary function     
   FEV1, L 1.02 ± 0.39* 1.18 ± 0.42 1.14 ± 0.38 0.002
% predicted 42 ± 15* 49 ± 15 49 ± 17 0.002
   FVC, L 2.7 ± 0.8 2.6 ± 0.8 2.5 ± 0.9 NS
% predicted 86 ± 22 83 ± 21 82 ± 23 NS
   FEV1/FVC, % 40 ± 10* 45 ± 12* 49 ± 12 0.001
   FRC, L 5.0 ± 1.6† 4.4 ± 1.5 4.1 ± 1.7 <0.001
% predicted 159 ± 42† 142 ± 41 135 ± 45 <0.001
   RV, L 4.2 ± 1.4* 3.6 ± 1.4 3.5 ± 1.5 0.002
% predicted 178 ± 60* 157 ± 58 151 ± 64 0.006
   TLC, L 6.8 ± 1.7* 6.3 ± 1.7 6.1 ± 1.8 0.01
% predicted 121 ± 22* 112 ± 21 110 ± 23 0.001
   IC, L 1.8 ± 0.6 2.0 ± 0.6 2.0 ± 0.6 NS
% predicted 73 ± 21 77 ± 20 81 ± 19 NS
   IC/TLC, % 28 ± 8* 32 ± 9 33 ± 8 <0.001
Incremental exercise test     
   Peak V ˙ O 2 , L·min-1 0.85 ± 0.29* 1.02 ± 0.32* 1.12 ± 0.40 0.02
   Peak V ˙ O 2 , % predicted 61 ± 36* 75 ± 56* 87 ± 69 0.01
   Peak work capacity, Watt 59 ± 22 69 ± 29 65 ± 29 NS
   Peak work capacity, % predicted 57 ± 28 64 ± 41 64 ± 37 NS
Constant exercise test     
   CET time, s 367 ± 230 324 ± 201 338 ± 203 NS
6-minute walking test     
   6MWT, m 407 ± 75 391 ± 78 342 ± 79* 0.001
   Work-walk, m·kg 23296 ± 5902* 29590 ± 8045* 32779 ± 11078* <0.001
Quality of life     
   SGRQ total score 45 ± 17 45 ± 16 45 ± 18 NS
   SGRQ symptoms score 53 ± 23 51 ± 22 50 ± 24 NS
   SGRQ activity score 65 ± 20 65 ± 20 65 ± 22 NS
   SGRQ impact score 32 ± 18 32 ± 17 32 ± 19 NS
Pulmonary rehabilitation     
   Duration of rehabilitation (weeks) 8.5 ± 1.7 8.5 ± 1.7 8.4 ± 1.7 NS
   Home based rehabilitation, n (%) 23 (26) 27 (28) 21 (27) NS
  1. Values are mean ± SD. Definitions of abbreviations: FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; FRC: functional residual capacity; RV: residual volume; TLC: total lung capacity; IC: inspiratory capacity; V ˙ O 2 : oxygen consumption; CET: constant exercise test; 6MWT: 6-minutes walking test distance; SGRQ: St-George's respiratory questionnaire; NS: not significantly different. * = significantly different than the other two groups, p < 0.05. † = significantly different than obese group, p < 0.05.