Figure 1

TNFα production in bronchoalveolar lavage fluid. TNFα was measured by ELISA at the timepoints indicated. The 0 h sample was collected prior to the second pulmonary challenge. Data are represented as the mean ± SEM, in some data points the symbol is larger than the SEM. Experiments were done a minimum of 3 times with 3-4 mice per group, per experiment. ***p ≤ 0.0001 comparing the LPS-reduced HDE group to the HDE group by Student's t-test.