Skip to main content

Advertisement

Table 1 Characteristics of the subjects in the plasma analyses

From: Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma

Variable Young   Middle aged/elderly   
  Non-smokers Smokers Non-smokers Smokers COPD
Subjects, n 28 35 34 64 40
Age, yr 20 ± 0.2 20 ± 0.1 56 ± 1.7 52 ± 1.0 61 ± 1.4**
Sex, M/F 26/2 34/1 9/25 40/24** 31/9***
Pack years, yr 0 5.0 ± 0.43††† 0 30.5 ± 1.78*** 39.6 ± 2.39***
Post bronchodilator      
   FVC (l) 5.5 ± 0.17 5.4 ± 0.14 3.6 ± 0.11 4.0 ± 0.11 3.8 ± 0.15
   FEV1 (l) 4.8 ± 0.14 4.7 ± 0.11 3.0 ± 0.09 3.3 ± 0.09 2.3 ± 0.12***
   FEV1 (% predicted) 98 ± 1.2 100 ± 1.6 106 ± 2.3 95 ± 1.5*** 71 ± 2.7***
   FEV1/FVC 88 ± 1.0 88 ± 0.8 84 ± 1.0 83 ± 0.6 61 ± 1.5***
  1. Data are shown as mean ± SEM
  2. COPD, chronic obstructive pulmonary disease; FVC, Forced vital capacity; FEV1, Forced expiratory volume in one second
  3. p < 0.05; ††p < 0.01; †††p < 0.001 (vs young non-smokers, Mann-Whitney U test or Chi-square test)
  4. *p < 0.05; **p < 0.01; ***p < 0.001 (vs middle aged/elderly non-smokers, Mann-Whitney U test or Chi-square test)