Skip to main content

Table 1 Characteristics of the subjects in the plasma analyses

From: Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma

Variable

Young

 

Middle aged/elderly

  
 

Non-smokers

Smokers

Non-smokers

Smokers

COPD

Subjects, n

28

35

34

64

40

Age, yr

20 ± 0.2

20 ± 0.1

56 ± 1.7

52 ± 1.0

61 ± 1.4**

Sex, M/F

26/2

34/1

9/25

40/24**

31/9***

Pack years, yr

0

5.0 ± 0.43†††

0

30.5 ± 1.78***

39.6 ± 2.39***

Post bronchodilator

     

   FVC (l)

5.5 ± 0.17

5.4 ± 0.14

3.6 ± 0.11

4.0 ± 0.11

3.8 ± 0.15

   FEV1 (l)

4.8 ± 0.14

4.7 ± 0.11

3.0 ± 0.09

3.3 ± 0.09

2.3 ± 0.12***

   FEV1 (% predicted)

98 ± 1.2

100 ± 1.6

106 ± 2.3

95 ± 1.5***

71 ± 2.7***

   FEV1/FVC

88 ± 1.0

88 ± 0.8

84 ± 1.0

83 ± 0.6

61 ± 1.5***

  1. Data are shown as mean ± SEM
  2. COPD, chronic obstructive pulmonary disease; FVC, Forced vital capacity; FEV1, Forced expiratory volume in one second
  3. †p < 0.05; ††p < 0.01; †††p < 0.001 (vs young non-smokers, Mann-Whitney U test or Chi-square test)
  4. *p < 0.05; **p < 0.01; ***p < 0.001 (vs middle aged/elderly non-smokers, Mann-Whitney U test or Chi-square test)
Back to article page

BMC Pulmonary Medicine

ISSN: 1471-2466

Contact us