Table 3 Characteristics of the HIV infected patients diagnosed with TB
From: Incidence, risk factors and mortality of tuberculosis in Danish HIV patients 1995-2007
Year of TB diagnosis | TB 1995-2007 N = 120 | TB 1995-1996 N = 15 | TB 1997-1999 N = 25 | TB 2000-2007 N = 80 | P value | |
|---|---|---|---|---|---|---|
Males | 70 (58.3%) | 11 (73.3%) | 16 (64%) | 43 (53.8%) | 0.30 | |
Median age, years (IQR*) | 35.4 (30.8-42.5) | 33.6 (31.2-38.5) | 35.1 (29.6 - 45.5) | 37.1 (30.8-42.9) | 0.41 | |
Birth country/region | 0.80 | |||||
Denmark | 45 (37.5%) | 5 (33.3%) | 11 (44.0%) | 29 (36.3%) | ||
Europe | 4 (3.3%) | 1 (6.7%) | 1 (4.0%) | 2 (2.5%) | ||
Africa | 45 (37.5%) | 7 (46.7%) | 10 (40.0%) | 28 (35.0%) | ||
Asia | 22 (18.3%) | 2 (13.3%) | 2 (8.0%) | 18 (22.5%) | ||
Other | 4 (3.3%) | 0 (0.0%) | 1 (4.0%) | 3 (3.8%) | ||
Transmission of HIV | 0.96 | |||||
Homosexual | 18 (15.0%) | 3 (20.0%) | 4 (16.0%) | 11 (13.8%) | ||
Heterosexual | 72 (60.0%) | 9 (60.0%) | 16 (64.0%) | 47 (58.8%) | ||
IDU | 15 (12.5%) | 2 (13.3%) | 2 (8.0%) | 11 (13.8%) | ||
Other | 15 (12.5%) | 1 (6.7%) | 3 (12.0%) | 11 (13.8%) | ||
Diagnosis of alcohol abuse | 13 (10.8%) | 1 (6.7%) | 2 (8.0%) | 10 (12.5%) | 0.38 | |
Median HIV RNA at time of TB diagnosis, log10 copies/mL (IQR*)** | 4.9 (3.6-5.9) | 3.0 (2.7-3.9) | 4.9 (4.2-5.9) | 4.9 (3.6-5.9) | 0.87 | |
Median CD4cell count at time of TB diagnosis, cells/μL (IQR*)*** | 120 (50-280) | 150 (8-175) | 110 (42-295) | 120 (60 - 362) | 0.94 | |
CD4 cell count < = 200 cells/μL at time of TB diagnosis*** | 69 (67.0%) | 9 (81.8%) | 14 (66.7%) | 46 (64.8%) | 0.54 | |
Caucasians | 43 (35.8%) | 5 (33.3%) | 11 (44.0%) | 27 (33.8%) | 0.67 | |
HAART started before TB diagnosis | 28 (23.3%) | 1 (6.7%) | 5 (20.0%) | 22 (27.5%) | 0.20 | |
HAART during study period | 104 (86.7%) | 12 (80%) | 23 (92.0%) | 69 (86.3%) | 0.55 | |
Emigrated during study period | 7 (5.8%) | 1 (6.7%) | 1 (4%) | 5 (6.3%) | 0.91 | |
Dead during study period | 19 (15.8%) | 3 (20.0%) | 6 (24.0%) | 10 (12.5%) | 0.35 | |
Death within 2 yrs after HIV diagnosis | 17 (14.2%) | 3 (20.0%) | 6 (24.0%) | 8 (10.0%) | 0.17 | |
Median time from HIV to TB, months (IQR*) | 0.6 (< 0.1-7.2) | 0.6 (0.1-2.9) | 0.4 (< 0.1 - 2.6) | 0.8 (< 0.1-15.7) | 0.30 | |
Median time from TB to death, months (IQR*) | 12.6 (0.6-17.8) | 13.6 (0.0-58.8) | 10.8 (0.5-41.6) | 11.8 (1.7-17.7) | 0.95 | |