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Table 2 Hemodynamics and Cardiopulmonary exercise characteristics at baseline between survivors and nonsurvivors in patients with selective drug therapy (survival after 24 months)

From: Ventilatory efficiency testing as prognostic value in patients with pulmonary hypertension

 

Survivors

Nonsurvivors

p

 

(n = 87)

(n = 29)

 

PAP, mmHg

42.0 ± 2.5

39.6 ± 2.6

ns

CI, L*min-1*m-2

2.30 ± 0.12

2.31 ± 0.21

ns

PVR, dynes * s * cm-5

633.8 ± 68.2

594.1 ± 76.6

ns

RAP, mmHg

7.22 ± 0.79

8.55 ± 1.88

ns

W, watts

67.7 ± 8.0

35.7 ± 1.5

0.023

VO2, ml/min/kg

14.6 ± 1.4

10.9 ± 1.0

ns

AT, ml/min/kg

9.65 ± 0.87

7.09 ± 1.07

ns

O2 pulse, ml/min/beat

9.80 ± 0.81

7.79 ± 0.64

ns

Ve/VO2 - AT

42.1 ± 2.1

56.9 ± 2.6

0.001

Ve/VCO2 - AT

47.5 ± 2.2

64.4 ± 2.3

< 0.001

AaDO2 – peak exercise, mmHg

52.8 ± 2.8

67.5 ± 4.2

0.009

a-et CO2, mmHg

6.8 ± 0.8

10.5 ± 1.1

0.014

Ve/VCO2 slope

47.0 ± 3.2

65.4 ± 7.5

0.014

  1. PAP = mean pulmonary artery pressure.
  2. CI = cardiac index.
  3. PVR = pulmonary vascular resistance.
  4. RAP = mean right atrial pressure.
  5. W = work capacity.
  6. VO2 = peak oxygen uptake.
  7. AT = anaerobic threshold.
  8. O2 pulse = oxygen pulse.
  9. Ve/VO2 = oxygen equivalent at anaerobic threshold.
  10. Ve/VCO2 = carbon dioxide equivalent at anaerobic threshold.
  11. AaDO2 = alveolar-arterial oxygen difference at peak exercise.
  12. a-et CO2 = arterial-endexpiratory carbon dioxide difference at peak pexercise.
  13. Ve – VCO2 slope = slope of minute ventilation versus carbon dioxide output.
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BMC Pulmonary Medicine

ISSN: 1471-2466

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